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The map label for this gene is degP [C]

Identifier: 156938049

GI number: 156938049

Start: 1124107

End: 1125192

Strand: Direct

Name: degP [C]

Synonym: Igni_1262

Alternate gene names: 156938049

Gene position: 1124107-1125192 (Clockwise)

Preceding gene: 156938046

Following gene: 156938051

Centisome position: 86.63

GC content: 57.64

Gene sequence:

>1086_bases
GTGAGGGCGTTCGGGAGCCTCATGGCGCTCGAAGCCTTGGCACTCGTCGCGCTCGTCGCGGCCTCAGTGGTCCCCTACTT
CTTGAACAAGTCGAGCGAGAGGCTGTTCACCCCCTTCCCCGGCTTCGTGGCACTGCGCTTCCCCGTGGAGGGCAAGCCCA
CCCAAGGCAAGTCTAGAATAGTTGAAGCGTCTTTGGACTTAGCAATCGTCATCACAGTAATACTAATGCTCATCGGATAT
ACGTTAATCGTACGGACGCTCGTCCCGAAGTCCCCGGCGGGGGGCGCGTTCGTCCCCTTGATACCTGGGGTCACGGTGCC
GGTCAACCTACTGGTGAGTTTAATATGGATAATAGCTATTGCGGTCGTCGTACACGAGCTCTTCCACTACTTGGCGTGCG
TGTGGCAAGGGATAAGGGTGAGGAGCGCCGGAGTGGGGCTGCTGCTCTTCTTTCCAATAGCCTTCGTGGAGCCGGACGAG
GAAAACTTGATGAGGAGCCCTCCGAGGGCCAGGGCACGGGTCTACTCCGCCGGCCCCGCGGCCAACGGAGTTCTCGCCGC
CTTGGCGCTAGTCCTTATAACTGTATTGATTGAAAAGGGAGTGTACGTAATAGACGTGGAAGAGGGCAGTCCCGCGTGGG
CGGCTGGGATAAAGAAGGGCGACGTAATAATTGAAGTTAACGGCCAGAGGGTGAACAACCTAATAGACCTTAGGAAAGCC
ATCTCTTCCGGCGAACTGCTGAAGGTCGTGGTCTTGAGGGGGGAGGAGAAGGTCACGTTGCTCGTGAACAAGGACGGGAG
GGAGAGGATAGGAGTCTACGTGCTGCCTTGGGTGCCCAAGGGCCCCTTGAGGGGCCTCCCCCCAGAAGAGGCCGCGAAGG
CTGTACAAACGCTCTTCTGGACCCACGGGGTCAACTTAGGCCTTGGAGTGGTGAACGCGCTACCGATGTTCATAACTGAC
GGAGGGAAGTTGGTTTCCGAGGTAAAAAGGGTTAGGAGGCTTTCCTCCGTAGCGGACGCGTTCCAATTGATCACTGTAAT
ACTGTTCGTCCACGCGTTGGTCGGATCCCTCAGGCCCTTAGCTTGA

Upstream 100 bases:

>100_bases
CCTCCTGCCGGCTATTATTACGCATACCCTACCGACCTCGATCGCCGGCATGTAACTTCGACCCCGGCTGCGCTAGCTTG
CAAGGTCTTTAAGGGTTGCC

Downstream 100 bases:

>100_bases
GACGGCCTCCTCGTATACCCTCTTTATGGCCTCGGCCGCCCTCTTCAGCCTCTCCCTCTCCTCCTCGTTGAGCAGCTGGG
GCAGCGGGACCAGCCTCCCG

Product: peptidase M50

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MRAFGSLMALEALALVALVAASVVPYFLNKSSERLFTPFPGFVALRFPVEGKPTQGKSRIVEASLDLAIVITVILMLIGY
TLIVRTLVPKSPAGGAFVPLIPGVTVPVNLLVSLIWIIAIAVVVHELFHYLACVWQGIRVRSAGVGLLLFFPIAFVEPDE
ENLMRSPPRARARVYSAGPAANGVLAALALVLITVLIEKGVYVIDVEEGSPAWAAGIKKGDVIIEVNGQRVNNLIDLRKA
ISSGELLKVVVLRGEEKVTLLVNKDGRERIGVYVLPWVPKGPLRGLPPEEAAKAVQTLFWTHGVNLGLGVVNALPMFITD
GGKLVSEVKRVRRLSSVADAFQLITVILFVHALVGSLRPLA

Sequences:

>Translated_361_residues
MRAFGSLMALEALALVALVAASVVPYFLNKSSERLFTPFPGFVALRFPVEGKPTQGKSRIVEASLDLAIVITVILMLIGY
TLIVRTLVPKSPAGGAFVPLIPGVTVPVNLLVSLIWIIAIAVVVHELFHYLACVWQGIRVRSAGVGLLLFFPIAFVEPDE
ENLMRSPPRARARVYSAGPAANGVLAALALVLITVLIEKGVYVIDVEEGSPAWAAGIKKGDVIIEVNGQRVNNLIDLRKA
ISSGELLKVVVLRGEEKVTLLVNKDGRERIGVYVLPWVPKGPLRGLPPEEAAKAVQTLFWTHGVNLGLGVVNALPMFITD
GGKLVSEVKRVRRLSSVADAFQLITVILFVHALVGSLRPLA
>Mature_361_residues
MRAFGSLMALEALALVALVAASVVPYFLNKSSERLFTPFPGFVALRFPVEGKPTQGKSRIVEASLDLAIVITVILMLIGY
TLIVRTLVPKSPAGGAFVPLIPGVTVPVNLLVSLIWIIAIAVVVHELFHYLACVWQGIRVRSAGVGLLLFFPIAFVEPDE
ENLMRSPPRARARVYSAGPAANGVLAALALVLITVLIEKGVYVIDVEEGSPAWAAGIKKGDVIIEVNGQRVNNLIDLRKA
ISSGELLKVVVLRGEEKVTLLVNKDGRERIGVYVLPWVPKGPLRGLPPEEAAKAVQTLFWTHGVNLGLGVVNALPMFITD
GGKLVSEVKRVRRLSSVADAFQLITVILFVHALVGSLRPLA

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To S.solfataricus C04034 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR001193
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38800; Mature: 38800

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFGSLMALEALALVALVAASVVPYFLNKSSERLFTPFPGFVALRFPVEGKPTQGKSRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEECCCCCCCCCHHHH
VEASLDLAIVITVILMLIGYTLIVRTLVPKSPAGGAFVPLIPGVTVPVNLLVSLIWIIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AVVVHELFHYLACVWQGIRVRSAGVGLLLFFPIAFVEPDEENLMRSPPRARARVYSAGPA
HHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHEEEECCCC
ANGVLAALALVLITVLIEKGVYVIDVEEGSPAWAAGIKKGDVIIEVNGQRVNNLIDLRKA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCEEEEECCHHHHHHHHHHHH
ISSGELLKVVVLRGEEKVTLLVNKDGRERIGVYVLPWVPKGPLRGLPPEEAAKAVQTLFW
HCCCCEEEEEEEECCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
THGVNLGLGVVNALPMFITDGGKLVSEVKRVRRLSSVADAFQLITVILFVHALVGSLRPL
HCCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
A
C
>Mature Secondary Structure
MRAFGSLMALEALALVALVAASVVPYFLNKSSERLFTPFPGFVALRFPVEGKPTQGKSRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEECCCCCCCCCHHHH
VEASLDLAIVITVILMLIGYTLIVRTLVPKSPAGGAFVPLIPGVTVPVNLLVSLIWIIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
AVVVHELFHYLACVWQGIRVRSAGVGLLLFFPIAFVEPDEENLMRSPPRARARVYSAGPA
HHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHEEEECCCC
ANGVLAALALVLITVLIEKGVYVIDVEEGSPAWAAGIKKGDVIIEVNGQRVNNLIDLRKA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCEEEEECCHHHHHHHHHHHH
ISSGELLKVVVLRGEEKVTLLVNKDGRERIGVYVLPWVPKGPLRGLPPEEAAKAVQTLFW
HCCCCEEEEEEEECCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
THGVNLGLGVVNALPMFITDGGKLVSEVKRVRRLSSVADAFQLITVILFVHALVGSLRPL
HCCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]