BacMap

Definition	Ignicoccus hospitalis KIN4/I chromosome, complete genome.
Accession	NC_009776
Length	1,297,538

Click here to switch to the map view.

The map label for this gene is yvrD [H]

Identifier: 156937826

GI number: 156937826

Start: 924861

End: 925646

Strand: Reverse

Name: yvrD [H]

Synonym: Igni_1036

Alternate gene names: 156937826

Gene position: 925646-924861 (Counterclockwise)

Preceding gene: 156937827

Following gene: 156937823

Centisome position: 71.34

GC content: 61.45

Gene sequence:

>786_bases
GTGGACTTGGGGCTGGCGGGCAAGAGGGTCTTGGTCACGGCCTCCACTAAGGGCATAGGCCTCGCTGTGGCGAGGGAGTT
CCTAAAGGAGGGCGCGAAGGTGTTCATAAGCTCCAGGAGGGAGGAGAACGTCAAAAGAGCCTTGGAGGAGCTCTCCCCCT
TGGGCGAGGTCCGGGGGACTACGGCGGACTTGAGGTCCAAGGAGGACAGGGAGAGGCTGGTGGGGGAGGCCAGGAAGGCC
CTCGGCGGGGTGGACGTCTTCGTCTTCAACTCCGGCGGCCCCCCTGCCAAGGCCTTCGAGGAGACGACCTTGGAGGACTG
GGAAGAAGCGTATAAGCTCTTGCTGGAGAGTGCCGCCCACTTGACCAAGCTGGTCCTCCCGGAGATGGTAGAGAGGGGGT
GGGGGAGGGTAGTTTACATAACTAGCGTGGCCATAAAGATGCCCTTGGAGGGCTTGGTGCTCTCCAACGCGGTTAGGGTC
GGGATAGCGGGCTTAATGAAGACCTTGGTTAAGGAGTACGCCGGGAAGGGGATTACGTTCAACTCCGTCCTCCCCGGCTA
CACCCTCACCGAGAGGGTTAAGGAGGTCATCAAGAAGAAGGCGGAAATGGAGGGGAAGAGCTACGAGGAAGCCCTCAGGG
AGCTGAGCGACGCTATACCCCTCAAGAGGCTGGCGGAGCCGGAGGAGGTGGCTAGGGCTGTGGTGTTCCTAGCCTCCGAG
GCCGCCTCTTACGTGAACGGGGTCTCCTTGCAAGTGGACGGGGGGCTAGTGCCAACGCTCTTCTAA

Upstream 100 bases:

>100_bases
CTTGAGGAGGCACTTGGAGGAGGCTAGGAGGGTCTTCCCCCGCTCCTACGCCGCGGAGGACTTAACTAAGGTGGTTATAC
TGAAGTGAGCGGTGCCCCCC

Downstream 100 bases:

>100_bases
CACTTCCCTCACCCTCCTCCCCAGCTCCCCTAACCTAACCACCTCCCAGCCCTCCGCTTCCCCCGGCTCTTGCACCGCCA
TTATCCTCACCGGGGCAAGG

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDLGLAGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLGEVRGTTADLRSKEDRERLVGEARKA
LGGVDVFVFNSGGPPAKAFEETTLEDWEEAYKLLLESAAHLTKLVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRV
GIAGLMKTLVKEYAGKGITFNSVLPGYTLTERVKEVIKKKAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASE
AASYVNGVSLQVDGGLVPTLF

Sequences:

>Translated_261_residues
MDLGLAGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLGEVRGTTADLRSKEDRERLVGEARKA
LGGVDVFVFNSGGPPAKAFEETTLEDWEEAYKLLLESAAHLTKLVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRV
GIAGLMKTLVKEYAGKGITFNSVLPGYTLTERVKEVIKKKAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASE
AASYVNGVSLQVDGGLVPTLF
>Mature_261_residues
MDLGLAGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLGEVRGTTADLRSKEDRERLVGEARKA
LGGVDVFVFNSGGPPAKAFEETTLEDWEEAYKLLLESAAHLTKLVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRV
GIAGLMKTLVKEYAGKGITFNSVLPGYTLTERVKEVIKKKAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASE
AASYVNGVSLQVDGGLVPTLF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=39.1304347826087, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=36.1111111111111, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=35.9375, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=38.6740331491713, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=31.9066147859922, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=37.1134020618557, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.4655172413793, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=26.4591439688716, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=29.3172690763052, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.0632411067194, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503817, Length=239, Percent_Identity=24.6861924686192, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI32455239, Length=218, Percent_Identity=24.7706422018349, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031765, Length=218, Percent_Identity=24.7706422018349, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=24.4094488188976, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.8063241106719, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=31.9230769230769, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=29.1338582677165, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=28.515625, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=29.6442687747036, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=26.3565891472868, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.2945736434109, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=28.0155642023346, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789057, Length=231, Percent_Identity=25.5411255411255, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=28.1853281853282, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=32.2834645669291, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=32.03125, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=27.1653543307087, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=26.5917602996255, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=27.9527559055118, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=26.3358778625954, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=26.6932270916335, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=25.9398496240602, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=25.4901960784314, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=23.3962264150943, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=28.3088235294118, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=25.2873563218391, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=283, Percent_Identity=26.1484098939929, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=24.8, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=275, Percent_Identity=25.8181818181818, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=28.0769230769231, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.027027027027, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=24.904214559387, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=23.9382239382239, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=31.5508021390374, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=24.0458015267176, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=23.2558139534884, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=26.7441860465116, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.5490196078431, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=34.8837209302326, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=32.4427480916031, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=29.2, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=28.125, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=32.5581395348837, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640492, Length=172, Percent_Identity=27.3255813953488, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28363; Mature: 28363

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLAGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLGEVRGT
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TADLRSKEDRERLVGEARKALGGVDVFVFNSGGPPAKAFEETTLEDWEEAYKLLLESAAH
HHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTKLVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRVGIAGLMKTLVKEYAGKGITF
HHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
NSVLPGYTLTERVKEVIKKKAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASE
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
AASYVNGVSLQVDGGLVPTLF
HHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MDLGLAGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLGEVRGT
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TADLRSKEDRERLVGEARKALGGVDVFVFNSGGPPAKAFEETTLEDWEEAYKLLLESAAH
HHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTKLVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRVGIAGLMKTLVKEYAGKGITF
HHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
NSVLPGYTLTERVKEVIKKKAEMEGKSYEEALRELSDAIPLKRLAEPEEVARAVVFLASE
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
AASYVNGVSLQVDGGLVPTLF
HHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]