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The map label for this gene is purP [H]

Identifier: 156937734

GI number: 156937734

Start: 836750

End: 837850

Strand: Reverse

Name: purP [H]

Synonym: Igni_0943

Alternate gene names: 156937734

Gene position: 837850-836750 (Counterclockwise)

Preceding gene: 156937737

Following gene: 156937728

Centisome position: 64.57

GC content: 55.86

Gene sequence:

>1101_bases
TTGGGCCTGAGCGACGAAATGAAGGAGATTGTTAACAATTACGACAAGAAGCCCGCAATAGCGGCGGTAGCGAGCCACTC
CGCCTTGGACTTGTTCGACGGTGCAAAGGACGAAGGGTTCAGAACAATAGCTGTGTGCCAAAAGGGGAGGGAAAAGCCGT
ACATCAAGTTCAGCCGTGTGGTTGACGAGTGTATACTCCTAGAGAGGTACAAGGACGTCCTCCGCGAGGACGTCCAGAGG
AGGCTGAGGGAGGAGGCCGCGATCTTCGTACCCAACCGGAGCTTCGCCGTCTACGTCGGGTACGATGCAATAGAACAAGA
GTTCGAGGTCCCCGTGTTCGGGAACCGGTACTTGCTCCGGTGGGAGGAGAGGGTAGGCGAGAAGAACTACTACAAGCTCT
TGGACGAGGCTGGAATAAAGAGGCCCAAACTTTTCAACTCCCCCGAAGAGATAGACAGACCGGTCATCGTGAAGGTCCCA
GAAGCTAAGAGGAGGGTCGAGAGGGGCTTCTTCGTTGCCATGGATAAAGAGGACTACTGGAAGAGGGTGAAAGAGCTCAA
GGAAGCCGGCGTAATAGACGACGAAGGGCTCAAGAACGCGTCTATAGAGGAGTTGGTCTTGGGGGCTCACTTCAACATAA
ACTACTTCTACAGCCCCTTGTTAGAGGACCTAGAGCTGCACTCGGTTGACAGGAGGATACAGAGCGACTTGGACGGCTGG
TTAAGGCTGCCGGCTAGGGAGCAGCTGCGCTTGGCCGGCAACCCGAGGATGATAGAGGTCGGCCACCTTCCGGCCACCTT
GAGGGAGAGCTTATTGGAGAAAGTGTTCGACATGGGTGAGAAGTTCGTAGAAGCCGCGAGGAAGTTGGAACCTCCGGGAG
TGGTGGGGCCCTTCACACTTCAAGCGGTAGTTACGCCGGAGCTGGAGTTCGTGGTGTTCGACGTGGCCCCTAGGATAGGG
GGCGGGAACAACATATACATGGGGTTAGGGAGCCAGTACTCCAAGTTGCAGTTCGGGAGGCCTATAAGCTTGGGTCGGAG
GGTCGCCATGGAAATAAGGCTGGCTTGGGAGACCAAGAGGTTGGCAGAGCTCGTCACGTAG

Upstream 100 bases:

>100_bases
GAACCGTAAAAGCCTGGCGTTCAAGACTTCAGCGCCCTCGAGGGGTCCGGCGTGGGGTTTTCAAGGGCTCTAGGGCTAAG
TAGCTTTCGAGTGGAAGGCC

Downstream 100 bases:

>100_bases
GTTCCTCGACCTTCTTGAGCCTGCTTTTGTACATCTCCACTATCTCTCCACACGTGGTGGCGTCCTCCGGCCCCTTGTCG
GGCCTCCAGCGTATGAAACG

Product: 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein

Products: NA

Alternate protein names: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGLSDEMKEIVNNYDKKPAIAAVASHSALDLFDGAKDEGFRTIAVCQKGREKPYIKFSRVVDECILLERYKDVLREDVQR
RLREEAAIFVPNRSFAVYVGYDAIEQEFEVPVFGNRYLLRWEERVGEKNYYKLLDEAGIKRPKLFNSPEEIDRPVIVKVP
EAKRRVERGFFVAMDKEDYWKRVKELKEAGVIDDEGLKNASIEELVLGAHFNINYFYSPLLEDLELHSVDRRIQSDLDGW
LRLPAREQLRLAGNPRMIEVGHLPATLRESLLEKVFDMGEKFVEAARKLEPPGVVGPFTLQAVVTPELEFVVFDVAPRIG
GGNNIYMGLGSQYSKLQFGRPISLGRRVAMEIRLAWETKRLAELVT

Sequences:

>Translated_366_residues
MGLSDEMKEIVNNYDKKPAIAAVASHSALDLFDGAKDEGFRTIAVCQKGREKPYIKFSRVVDECILLERYKDVLREDVQR
RLREEAAIFVPNRSFAVYVGYDAIEQEFEVPVFGNRYLLRWEERVGEKNYYKLLDEAGIKRPKLFNSPEEIDRPVIVKVP
EAKRRVERGFFVAMDKEDYWKRVKELKEAGVIDDEGLKNASIEELVLGAHFNINYFYSPLLEDLELHSVDRRIQSDLDGW
LRLPAREQLRLAGNPRMIEVGHLPATLRESLLEKVFDMGEKFVEAARKLEPPGVVGPFTLQAVVTPELEFVVFDVAPRIG
GGNNIYMGLGSQYSKLQFGRPISLGRRVAMEIRLAWETKRLAELVT
>Mature_365_residues
GLSDEMKEIVNNYDKKPAIAAVASHSALDLFDGAKDEGFRTIAVCQKGREKPYIKFSRVVDECILLERYKDVLREDVQRR
LREEAAIFVPNRSFAVYVGYDAIEQEFEVPVFGNRYLLRWEERVGEKNYYKLLDEAGIKRPKLFNSPEEIDRPVIVKVPE
AKRRVERGFFVAMDKEDYWKRVKELKEAGVIDDEGLKNASIEELVLGAHFNINYFYSPLLEDLELHSVDRRIQSDLDGWL
RLPAREQLRLAGNPRMIEVGHLPATLRESLLEKVFDMGEKFVEAARKLEPPGVVGPFTLQAVVTPELEFVVFDVAPRIGG
GNNIYMGLGSQYSKLQFGRPISLGRRVAMEIRLAWETKRLAELVT

Specific function: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates [H]

COG id: COG1759

COG function: function code R; ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR009720
- InterPro:   IPR010672
- InterPro:   IPR013817 [H]

Pfam domain/function: PF06849 DUF1246; PF06973 DUF1297 [H]

EC number: NA

Molecular weight: Translated: 41997; Mature: 41866

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSDEMKEIVNNYDKKPAIAAVASHSALDLFDGAKDEGFRTIAVCQKGREKPYIKFSRV
CCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCEEHHHHHCCCCCCCHHHHHH
VDECILLERYKDVLREDVQRRLREEAAIFVPNRSFAVYVGYDAIEQEFEVPVFGNRYLLR
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECHHHHHHHCCCCCCCCEEEEE
WEERVGEKNYYKLLDEAGIKRPKLFNSPEEIDRPVIVKVPEAKRRVERGFFVAMDKEDYW
EHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCHHHHHHHCCEEEEECCHHHH
KRVKELKEAGVIDDEGLKNASIEELVLGAHFNINYFYSPLLEDLELHSVDRRIQSDLDGW
HHHHHHHHCCCCCCCCCCCCCHHHHEEECEECCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLPAREQLRLAGNPRMIEVGHLPATLRESLLEKVFDMGEKFVEAARKLEPPGVVGPFTL
HCCCCHHHHEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
QAVVTPELEFVVFDVAPRIGGGNNIYMGLGSQYSKLQFGRPISLGRRVAMEIRLAWETKR
EEEECCCEEEEEEECCCCCCCCCEEEEECCCCCHHHCCCCCHHHCCCEEEEEEEHHHHHH
LAELVT
HHHHCC
>Mature Secondary Structure 
GLSDEMKEIVNNYDKKPAIAAVASHSALDLFDGAKDEGFRTIAVCQKGREKPYIKFSRV
CCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCEEHHHHHCCCCCCCHHHHHH
VDECILLERYKDVLREDVQRRLREEAAIFVPNRSFAVYVGYDAIEQEFEVPVFGNRYLLR
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECHHHHHHHCCCCCCCCEEEEE
WEERVGEKNYYKLLDEAGIKRPKLFNSPEEIDRPVIVKVPEAKRRVERGFFVAMDKEDYW
EHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEECCHHHHHHHCCEEEEECCHHHH
KRVKELKEAGVIDDEGLKNASIEELVLGAHFNINYFYSPLLEDLELHSVDRRIQSDLDGW
HHHHHHHHCCCCCCCCCCCCCHHHHEEECEECCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LRLPAREQLRLAGNPRMIEVGHLPATLRESLLEKVFDMGEKFVEAARKLEPPGVVGPFTL
HCCCCHHHHEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
QAVVTPELEFVVFDVAPRIGGGNNIYMGLGSQYSKLQFGRPISLGRRVAMEIRLAWETKR
EEEECCCEEEEEEECCCCCCCCCEEEEECCCCCHHHCCCCCHHHCCCEEEEEEEHHHHHH
LAELVT
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA