Click here to switch to the map view.

The map label for this gene is cca [H]

Identifier: 156937642

GI number: 156937642

Start: 753560

End: 754870

Strand: Reverse

Name: cca [H]

Synonym: Igni_0849

Alternate gene names: 156937642

Gene position: 754870-753560 (Counterclockwise)

Preceding gene: 156937643

Following gene: 156937641

Centisome position: 58.18

GC content: 60.49

Gene sequence:

>1311_bases
TTGACCCCCTCCCGCTCCGAAGTAGAGAGGGAGGTCCTCGAGGAGCTTAGGCCTACGCGAGAGGAGGTGAGGCTGAGGGA
CGAGCTGTTCGTTAAAACGAAAAGCGTCCTCGAGGACGTCTTGAAGAAGAGGGGCTTGGAGGGCGAGGTGACCCTACAAG
GGAGCGCGAGGAAGGGGACTTGGCTCAGGGGCTCCTTGGAGCTGGACGTCTTCGTTTTGTTCCCGCCCAAGGACAAGGAG
TGGATAAAGGAGGTCGCCTTCCCGGCCCTCTTGGAAGCGGCCAGAGCGCTGGGCGAGCCCGAGGTGAGGTTCGCCGAGCA
CCCCTACGTGAGGACGGTCATCAAAGGAGTCCCGGTAGAGATAGTGCCAGCTTTTAAGGTAAGGAGCGCCAGCGAGGCAA
TAACCGCCGTGGACCGAACCCCGTTCCACACGGAGTGGTTCCTCCAACAAGTGAGGGCCTTGGGGGACTGGATAAGGGAC
GAGGTGAGGCTGCTCAAGGCCTTTATGAAGGGGATAGGAGTCTACGGAGCGGAGATAGCTGTTCAAGGGTTCTCCGGCTT
CTTGTGCGAGGTGCTCGCGACGTACTACAAGGGCTTCAGAGGGGTCATAGAGGCGGCGGCGCGGGAGTGGAGGCCCCCTA
CGGTGCTCGAGACCTCGCTGCCTAAGGAAGAGGCCTTGAAGAGGTTCGAAGGCCCGTTGGTGGTGCCGGACCCCACGGAC
CCCAAGCGCAACGCCGCGGCGGCCGTAAGCTTGAACGCTTACTCGACTTTCATAATAGCCTCCAAGCTCTACTCGGTCAA
GCCCTCGAAGAAGTTCTTCTTCCCCCCTAAGCCCGCCCCCGCGAGGCCCGTCTTGCCGACGTACGTGGTGGAGGTCCCCG
CGCTCCGCGCCCCTCCGGAGACCGTCTGGGGGGAGCTGAGGAGAGTGGCCAAGTCCTTGGTAAAGAACTTGAGGTCGCTC
GGGTTCGAAGTAACTAGGTTCGCGCTGTGGAGCGACGGGAGCGCAGCGAAGATCGCGCTCGAGTTCTTGCAAGACTCCTT
GCCCGAGTGGGAGGTAGCAAAGGGGCCGCCGGCTTGGAGCCCCCACGCTTTGAGGTTCCTCCGAGACAAGGAGTCTTGGT
GGGTGGACGAGGGGAGGTTATTCGCGAGGAGGAAGAGGAAGTACACCGAAGCTAAGAGCGCAATAGCCGACATATTGAAG
AAGTTGAAGGCAAAAAGCTTAATCCTCGAGAACAGTAAAATAGAAAGGGTTGAGCTCGCAGAAGAGAGGTGGCTGGCGGA
GTTCGTCTCGGGGAGGCCGCCTTGGTCTTGA

Upstream 100 bases:

>100_bases
TAGAGCTAGGAGAGCTCGAGGTAAAGAGCATAAGGCTGAAGAAGAGTACCTTGACGCCTAGGGGACCAATTTACGAGACG
TTGAGAGAGGTAGAGCTGGC

Downstream 100 bases:

>100_bases
AGGTTCGTCCCAAAGAGGCGCCCCTCTGCTTTCCCAAGGGGGAGTGTGAGCTGGGAGAGGTCTTAGAGGAGAGGGGCGTC
GAGTGGGTTTACAACTTCGG

Product: tRNA CCA-pyrophosphorylase

Products: NA

Alternate protein names: tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl- transferase; tRNA nucleotidyltransferase; tRNA-NT [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTPSRSEVEREVLEELRPTREEVRLRDELFVKTKSVLEDVLKKRGLEGEVTLQGSARKGTWLRGSLELDVFVLFPPKDKE
WIKEVAFPALLEAARALGEPEVRFAEHPYVRTVIKGVPVEIVPAFKVRSASEAITAVDRTPFHTEWFLQQVRALGDWIRD
EVRLLKAFMKGIGVYGAEIAVQGFSGFLCEVLATYYKGFRGVIEAAAREWRPPTVLETSLPKEEALKRFEGPLVVPDPTD
PKRNAAAAVSLNAYSTFIIASKLYSVKPSKKFFFPPKPAPARPVLPTYVVEVPALRAPPETVWGELRRVAKSLVKNLRSL
GFEVTRFALWSDGSAAKIALEFLQDSLPEWEVAKGPPAWSPHALRFLRDKESWWVDEGRLFARRKRKYTEAKSAIADILK
KLKAKSLILENSKIERVELAEERWLAEFVSGRPPWS

Sequences:

>Translated_436_residues
MTPSRSEVEREVLEELRPTREEVRLRDELFVKTKSVLEDVLKKRGLEGEVTLQGSARKGTWLRGSLELDVFVLFPPKDKE
WIKEVAFPALLEAARALGEPEVRFAEHPYVRTVIKGVPVEIVPAFKVRSASEAITAVDRTPFHTEWFLQQVRALGDWIRD
EVRLLKAFMKGIGVYGAEIAVQGFSGFLCEVLATYYKGFRGVIEAAAREWRPPTVLETSLPKEEALKRFEGPLVVPDPTD
PKRNAAAAVSLNAYSTFIIASKLYSVKPSKKFFFPPKPAPARPVLPTYVVEVPALRAPPETVWGELRRVAKSLVKNLRSL
GFEVTRFALWSDGSAAKIALEFLQDSLPEWEVAKGPPAWSPHALRFLRDKESWWVDEGRLFARRKRKYTEAKSAIADILK
KLKAKSLILENSKIERVELAEERWLAEFVSGRPPWS
>Mature_435_residues
TPSRSEVEREVLEELRPTREEVRLRDELFVKTKSVLEDVLKKRGLEGEVTLQGSARKGTWLRGSLELDVFVLFPPKDKEW
IKEVAFPALLEAARALGEPEVRFAEHPYVRTVIKGVPVEIVPAFKVRSASEAITAVDRTPFHTEWFLQQVRALGDWIRDE
VRLLKAFMKGIGVYGAEIAVQGFSGFLCEVLATYYKGFRGVIEAAAREWRPPTVLETSLPKEEALKRFEGPLVVPDPTDP
KRNAAAAVSLNAYSTFIIASKLYSVKPSKKFFFPPKPAPARPVLPTYVVEVPALRAPPETVWGELRRVAKSLVKNLRSLG
FEVTRFALWSDGSAAKIALEFLQDSLPEWEVAKGPPAWSPHALRFLRDKESWWVDEGRLFARRKRKYTEAKSAIADILKK
LKAKSLILENSKIERVELAEERWLAEFVSGRPPWS

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG1746

COG function: function code J; tRNA nucleotidyltransferase (CCA-adding enzyme)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006116
- InterPro:   IPR008229
- InterPro:   IPR002934
- InterPro:   IPR011068
- InterPro:   IPR015329 [H]

Pfam domain/function: PF01909 NTP_transf_2; PF09249 tRNA_NucTransf2 [H]

EC number: =2.7.7.21; =2.7.7.25 [H]

Molecular weight: Translated: 49401; Mature: 49269

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSRSEVEREVLEELRPTREEVRLRDELFVKTKSVLEDVLKKRGLEGEVTLQGSARKGT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
WLRGSLELDVFVLFPPKDKEWIKEVAFPALLEAARALGEPEVRFAEHPYVRTVIKGVPVE
EEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCCEE
IVPAFKVRSASEAITAVDRTPFHTEWFLQQVRALGDWIRDEVRLLKAFMKGIGVYGAEIA
EECCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
VQGFSGFLCEVLATYYKGFRGVIEAAAREWRPPTVLETSLPKEEALKRFEGPLVVPDPTD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCEECCCCCC
PKRNAAAAVSLNAYSTFIIASKLYSVKPSKKFFFPPKPAPARPVLPTYVVEVPALRAPPE
CCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHH
TVWGELRRVAKSLVKNLRSLGFEVTRFALWSDGSAAKIALEFLQDSLPEWEVAKGPPAWS
HHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
PHALRFLRDKESWWVDEGRLFARRKRKYTEAKSAIADILKKLKAKSLILENSKIERVELA
HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EERWLAEFVSGRPPWS
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPSRSEVEREVLEELRPTREEVRLRDELFVKTKSVLEDVLKKRGLEGEVTLQGSARKGT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
WLRGSLELDVFVLFPPKDKEWIKEVAFPALLEAARALGEPEVRFAEHPYVRTVIKGVPVE
EEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCCEE
IVPAFKVRSASEAITAVDRTPFHTEWFLQQVRALGDWIRDEVRLLKAFMKGIGVYGAEIA
EECCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
VQGFSGFLCEVLATYYKGFRGVIEAAAREWRPPTVLETSLPKEEALKRFEGPLVVPDPTD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCEECCCCCC
PKRNAAAAVSLNAYSTFIIASKLYSVKPSKKFFFPPKPAPARPVLPTYVVEVPALRAPPE
CCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHH
TVWGELRRVAKSLVKNLRSLGFEVTRFALWSDGSAAKIALEFLQDSLPEWEVAKGPPAWS
HHHHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
PHALRFLRDKESWWVDEGRLFARRKRKYTEAKSAIADILKKLKAKSLILENSKIERVELA
HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EERWLAEFVSGRPPWS
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]