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The map label for this gene is livM [H]

Identifier: 156937523

GI number: 156937523

Start: 656797

End: 657825

Strand: Direct

Name: livM [H]

Synonym: Igni_0730

Alternate gene names: 156937523

Gene position: 656797-657825 (Clockwise)

Preceding gene: 156937522

Following gene: 156937524

Centisome position: 50.62

GC content: 52.87

Gene sequence:

>1029_bases
ATGGATAAGGTCGGCGCGCTCCTAGGGTTACTGATCTTGGGGGTCCTCGCGGCTCTGTTTTCGGTAAGCCCGAGCTACGC
TATTGACGTAATATTCTTCATAGCGTTCTACGCGATAGCTGCGCTAAGCTTAAACTTAGAATATGGCTACACAGGGCTCA
ACAACTTCGGACAAGTAGCTTTCATCGCTGTAGGCGCTTACACGGCCGGCGTCTTGTCGTCAGCCTTCCACTTGCCTTTC
GTCTACTGCCTACTGGCAGCCGCGTTGGCCGGAGGCCTCTTAGGGGCGTTCGTCGCAGTGCCTACAGTCAAGCTCCGCGA
GGACTACTTGGGCATGGCAACAATAATCATAGGAGAGATGATAAGGATCCTCTTGCGAAACACTCCTACGGAGAGCGTCT
GGGGCGGCGTCTTTGGGCTAAGGGGGATAAACCCCGTCTTCGCGTACATAAAGGACCCACTCGCGAGGCAAGGGGCCTTC
GTGCTACTGACGCTCTCGCTCCTCGCTTTGACTTATTGGTTAGTCGACAAGTGGGGCAACTCGCCATTGGGCCGAGTCCT
AAAGAGCATAAGGGACGACGAACTGGCGTCTAAGAGCGTTGGTAAGTTTACTTATCGCTACAAGCTGATAACTATGTTCG
TGGGCAGCGCCCTCGCGGGCGTCGCCGGCGCGCTCTACGCGTTCTACTTCCTCTACTTGAACCCCGACGTCTTTATGCCT
CTAATAACGTTCATGATATGGATAATGGTAATAATGGGCGGAGTAGCTAACAACTACGGAGTCGTAGTCGGAAGTGCGAT
AGTGATATTGATAAATAGGTTGACCCAAATAGCTAAGGATTATATAAACCTACCGATAGAGCCCAACTACTTCCAGGCTA
TGATGGTCGGTATACTGATAATAGTGTTCCTAATGTTTAGGCCCCAGGGTCTGGTGGTAGAAAAAGTTGTGAGGACGCCG
GCGTGGAGCGTGTTGAAGAGGGCAGAAGAAGAGGGCAGGGCCAAGCCGCCAGGGGGTGAGGAGCAGTGA

Upstream 100 bases:

>100_bases
GTTTATGATACCTTTCTCCGTGTTCCTCTTAGTTCTTTTCGTTAAGCCAGAGGGGATAGCCGGCATTCGGAGGAGGAAGG
CGTAACTGGGGGTGTTGGGT

Downstream 100 bases:

>100_bases
GCGACAACATCTTGGAAGTACAAAACGTGAAGAAGCGCTTCGGGGGCGTAGTGGCCCTCGACGGAGTTACAATGAGCGTT
AAGAGAGGAAGCATGACTGC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDKVGALLGLLILGVLAALFSVSPSYAIDVIFFIAFYAIAALSLNLEYGYTGLNNFGQVAFIAVGAYTAGVLSSAFHLPF
VYCLLAAALAGGLLGAFVAVPTVKLREDYLGMATIIIGEMIRILLRNTPTESVWGGVFGLRGINPVFAYIKDPLARQGAF
VLLTLSLLALTYWLVDKWGNSPLGRVLKSIRDDELASKSVGKFTYRYKLITMFVGSALAGVAGALYAFYFLYLNPDVFMP
LITFMIWIMVIMGGVANNYGVVVGSAIVILINRLTQIAKDYINLPIEPNYFQAMMVGILIIVFLMFRPQGLVVEKVVRTP
AWSVLKRAEEEGRAKPPGGEEQ

Sequences:

>Translated_342_residues
MDKVGALLGLLILGVLAALFSVSPSYAIDVIFFIAFYAIAALSLNLEYGYTGLNNFGQVAFIAVGAYTAGVLSSAFHLPF
VYCLLAAALAGGLLGAFVAVPTVKLREDYLGMATIIIGEMIRILLRNTPTESVWGGVFGLRGINPVFAYIKDPLARQGAF
VLLTLSLLALTYWLVDKWGNSPLGRVLKSIRDDELASKSVGKFTYRYKLITMFVGSALAGVAGALYAFYFLYLNPDVFMP
LITFMIWIMVIMGGVANNYGVVVGSAIVILINRLTQIAKDYINLPIEPNYFQAMMVGILIIVFLMFRPQGLVVEKVVRTP
AWSVLKRAEEEGRAKPPGGEEQ
>Mature_342_residues
MDKVGALLGLLILGVLAALFSVSPSYAIDVIFFIAFYAIAALSLNLEYGYTGLNNFGQVAFIAVGAYTAGVLSSAFHLPF
VYCLLAAALAGGLLGAFVAVPTVKLREDYLGMATIIIGEMIRILLRNTPTESVWGGVFGLRGINPVFAYIKDPLARQGAF
VLLTLSLLALTYWLVDKWGNSPLGRVLKSIRDDELASKSVGKFTYRYKLITMFVGSALAGVAGALYAFYFLYLNPDVFMP
LITFMIWIMVIMGGVANNYGVVVGSAIVILINRLTQIAKDYINLPIEPNYFQAMMVGILIIVFLMFRPQGLVVEKVVRTP
AWSVLKRAEEEGRAKPPGGEEQ

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=305, Percent_Identity=29.1803278688525, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 37237; Mature: 37237

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00306 CASEIN_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVGALLGLLILGVLAALFSVSPSYAIDVIFFIAFYAIAALSLNLEYGYTGLNNFGQVA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
FIAVGAYTAGVLSSAFHLPFVYCLLAAALAGGLLGAFVAVPTVKLREDYLGMATIIIGEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IRILLRNTPTESVWGGVFGLRGINPVFAYIKDPLARQGAFVLLTLSLLALTYWLVDKWGN
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
SPLGRVLKSIRDDELASKSVGKFTYRYKLITMFVGSALAGVAGALYAFYFLYLNPDVFMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LITFMIWIMVIMGGVANNYGVVVGSAIVILINRLTQIAKDYINLPIEPNYFQAMMVGILI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVFLMFRPQGLVVEKVVRTPAWSVLKRAEEEGRAKPPGGEEQ
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDKVGALLGLLILGVLAALFSVSPSYAIDVIFFIAFYAIAALSLNLEYGYTGLNNFGQVA
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
FIAVGAYTAGVLSSAFHLPFVYCLLAAALAGGLLGAFVAVPTVKLREDYLGMATIIIGEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IRILLRNTPTESVWGGVFGLRGINPVFAYIKDPLARQGAFVLLTLSLLALTYWLVDKWGN
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
SPLGRVLKSIRDDELASKSVGKFTYRYKLITMFVGSALAGVAGALYAFYFLYLNPDVFMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LITFMIWIMVIMGGVANNYGVVVGSAIVILINRLTQIAKDYINLPIEPNYFQAMMVGILI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVFLMFRPQGLVVEKVVRTPAWSVLKRAEEEGRAKPPGGEEQ
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]