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The map label for this gene is argC

Identifier: 156937521

GI number: 156937521

Start: 654296

End: 655366

Strand: Reverse

Name: argC

Synonym: Igni_0728

Alternate gene names: 156937521

Gene position: 655366-654296 (Counterclockwise)

Preceding gene: 156937527

Following gene: 156937516

Centisome position: 50.51

GC content: 56.58

Gene sequence:

>1071_bases
ATGACGTATGAGGTAGCGATAGTCGGAGCCTCCGGTTACACCGGAGGCGAGTTGCTAAGGGTACTCGCAGTACACCCCGA
CGTGAACGTGAAAGTGGTCACCTCTAGGGAATACGCCAACAAGCCCGTCTACTATGCCCACCCTCACTTGAGGGGGATAT
ACCCAGCGTCCTTGAAGTTTAAGAGGTTAGACGACCCTGACCAGCTCAGCGACGTCGTAGGCGACGTGGACCTGGTCTTC
CTCGCCCTTCCCCACAAGGTGTCCTTGCATTACGTGCCCAAGGCTTTGGAAGTAGGATATAAGGTAGTGGACTTAAGTGC
CGACTATCGTCTCAAGCGGGTTGAAGATTACAAAACTTGGTACGGCTACGAACACCCTTACCCGGACTTGCTCGAAAAGG
CCGTCTACGGCCTCCCGGAACTTTACGGAGACAAAATAAGGGGCGCCCAGCTCGTTGCTAACCCCGGCTGTAACGCAACT
AGCTCCATCTTGGCCGTCTTGCCCCCAGCGGCTGAAAGAATAATCGACTTGGACCGGATAGTGGTTGACGTCAAGGTGGG
GAGCTCCGAGGCGGGCGCCAAGCCCTACAGAGGGGGTCATCACCCGGAGAGGGAAGGCACGGCCAGGCCTTACGACGCAG
AAGGTCATAGACACGTAGCGGAGCTGGAGCAGGTTATAAGGGACTATACCGGGAGAGACGTCAAGGTAGGGTTTACCCCT
CACGCCGTGAGCATGATAAGGGGGTCACTCGCCTCAGCGTATTCTTGGCTTACGAAAGACTTAGCGCCGCTGGACGTCCA
AAGGATTTATGCGAAGTATTACGCGGGCAAGAAGTTCGTCAAGATAGTGAGGGGGGCGCCCATGCCTTACCCGGACGTGA
AGAACGTCTACGGCAGCAACTACGCCGAGGTCGGGTTCGCCTTGGACAAGAGGGTTGGGAGGCTAGCCATGTTCGCGGCG
ATAGACAACTTGATGAAGGGGGCGGCGGGGACGGCGGTGCAAAATATGAATTTGATGTTGGGCATGGATGAGGACGAGGG
CTTGAAGAACCTCGTTCCGGTGCGGCCCTAA

Upstream 100 bases:

>100_bases
ATTATTTGCCCGCCCCGACTTCGCTTAACTTTTAATATCGTTTTGCTTTATAGGTATAAGAGTTAAATCATGACGTCCTA
GCGAGAGCCGGGGAAGGTTA

Downstream 100 bases:

>100_bases
TAACCCAACGGGTTTGTGTTGGGCGGCGTTATATCATACGTCACCAGCGAAGTCTCTATCAATAGAGCCTTTCCGGACTT
ATTGAGGTAGTTTATGGCGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTYEVAIVGASGYTGGELLRVLAVHPDVNVKVVTSREYANKPVYYAHPHLRGIYPASLKFKRLDDPDQLSDVVGDVDLVF
LALPHKVSLHYVPKALEVGYKVVDLSADYRLKRVEDYKTWYGYEHPYPDLLEKAVYGLPELYGDKIRGAQLVANPGCNAT
SSILAVLPPAAERIIDLDRIVVDVKVGSSEAGAKPYRGGHHPEREGTARPYDAEGHRHVAELEQVIRDYTGRDVKVGFTP
HAVSMIRGSLASAYSWLTKDLAPLDVQRIYAKYYAGKKFVKIVRGAPMPYPDVKNVYGSNYAEVGFALDKRVGRLAMFAA
IDNLMKGAAGTAVQNMNLMLGMDEDEGLKNLVPVRP

Sequences:

>Translated_356_residues
MTYEVAIVGASGYTGGELLRVLAVHPDVNVKVVTSREYANKPVYYAHPHLRGIYPASLKFKRLDDPDQLSDVVGDVDLVF
LALPHKVSLHYVPKALEVGYKVVDLSADYRLKRVEDYKTWYGYEHPYPDLLEKAVYGLPELYGDKIRGAQLVANPGCNAT
SSILAVLPPAAERIIDLDRIVVDVKVGSSEAGAKPYRGGHHPEREGTARPYDAEGHRHVAELEQVIRDYTGRDVKVGFTP
HAVSMIRGSLASAYSWLTKDLAPLDVQRIYAKYYAGKKFVKIVRGAPMPYPDVKNVYGSNYAEVGFALDKRVGRLAMFAA
IDNLMKGAAGTAVQNMNLMLGMDEDEGLKNLVPVRP
>Mature_355_residues
TYEVAIVGASGYTGGELLRVLAVHPDVNVKVVTSREYANKPVYYAHPHLRGIYPASLKFKRLDDPDQLSDVVGDVDLVFL
ALPHKVSLHYVPKALEVGYKVVDLSADYRLKRVEDYKTWYGYEHPYPDLLEKAVYGLPELYGDKIRGAQLVANPGCNATS
SILAVLPPAAERIIDLDRIVVDVKVGSSEAGAKPYRGGHHPEREGTARPYDAEGHRHVAELEQVIRDYTGRDVKVGFTPH
AVSMIRGSLASAYSWLTKDLAPLDVQRIYAKYYAGKKFVKIVRGAPMPYPDVKNVYGSNYAEVGFALDKRVGRLAMFAAI
DNLMKGAAGTAVQNMNLMLGMDEDEGLKNLVPVRP

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=347, Percent_Identity=36.0230547550432, Blast_Score=176, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6320913, Length=358, Percent_Identity=29.3296089385475, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_IGNH4 (A8AAF8)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435317.1
- ProteinModelPortal:   A8AAF8
- SMR:   A8AAF8
- STRING:   A8AAF8
- GeneID:   5562500
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0728
- eggNOG:   arNOG05044
- HOGENOM:   HBG294213
- OMA:   GCMATAS
- ProtClustDB:   PRK00436
- BioCyc:   IHOS453591:IGNI_0728-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 39317; Mature: 39185

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYEVAIVGASGYTGGELLRVLAVHPDVNVKVVTSREYANKPVYYAHPHLRGIYPASLKF
CEEEEEEEECCCCCHHHHHEEEEECCCCCEEEEECHHHCCCCEEEECCCCCCCCCCCEEE
KRLDDPDQLSDVVGDVDLVFLALPHKVSLHYVPKALEVGYKVVDLSADYRLKRVEDYKTW
ECCCCHHHHHHHHCCCEEEEEECCCEEEEEECCHHHHCCEEEEEECCCCCHHHHHHHHHH
YGYEHPYPDLLEKAVYGLPELYGDKIRGAQLVANPGCNATSSILAVLPPAAERIIDLDRI
CCCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCHHHHHHEECCCHHHHHHHHCEE
VVDVKVGSSEAGAKPYRGGHHPEREGTARPYDAEGHRHVAELEQVIRDYTGRDVKVGFTP
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCH
HAVSMIRGSLASAYSWLTKDLAPLDVQRIYAKYYAGKKFVKIVRGAPMPYPDVKNVYGSN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHCCCC
YAEVGFALDKRVGRLAMFAAIDNLMKGAAGTAVQNMNLMLGMDEDEGLKNLVPVRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCHHCCCCCCC
>Mature Secondary Structure 
TYEVAIVGASGYTGGELLRVLAVHPDVNVKVVTSREYANKPVYYAHPHLRGIYPASLKF
EEEEEEEECCCCCHHHHHEEEEECCCCCEEEEECHHHCCCCEEEECCCCCCCCCCCEEE
KRLDDPDQLSDVVGDVDLVFLALPHKVSLHYVPKALEVGYKVVDLSADYRLKRVEDYKTW
ECCCCHHHHHHHHCCCEEEEEECCCEEEEEECCHHHHCCEEEEEECCCCCHHHHHHHHHH
YGYEHPYPDLLEKAVYGLPELYGDKIRGAQLVANPGCNATSSILAVLPPAAERIIDLDRI
CCCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCCCCHHHHHHEECCCHHHHHHHHCEE
VVDVKVGSSEAGAKPYRGGHHPEREGTARPYDAEGHRHVAELEQVIRDYTGRDVKVGFTP
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCH
HAVSMIRGSLASAYSWLTKDLAPLDVQRIYAKYYAGKKFVKIVRGAPMPYPDVKNVYGSN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHCCCC
YAEVGFALDKRVGRLAMFAAIDNLMKGAAGTAVQNMNLMLGMDEDEGLKNLVPVRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA