Definition Ignicoccus hospitalis KIN4/I chromosome, complete genome.
Accession NC_009776
Length 1,297,538

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The map label for this gene is hflB [C]

Identifier: 156937486

GI number: 156937486

Start: 625388

End: 627592

Strand: Reverse

Name: hflB [C]

Synonym: Igni_0693

Alternate gene names: 156937486

Gene position: 627592-625388 (Counterclockwise)

Preceding gene: 156937487

Following gene: 156937485

Centisome position: 48.37

GC content: 54.65

Gene sequence:

>2205_bases
GTGGCCGTCCCGGAGAGGGTCAACCCTAAAGGCGTTGAGCTAAAGGTAATGGAAGCTAAGCAGAAGGACGTAGGTCACGG
AAGGGTTAGAATAGACAGAATGATAATGGAACTCATAGGGGTCGCCCCCGGGGACGTAGTTGAGATAGAGGGCAAGAGGG
TCACTGCCGCCATAGCCTTGCCTGCGTACCCCGAAGACCAAGGATTAGACATAATCAGGATGGATGGCCTCATAAGGAAG
AACGCCGGCGTAACCGTGGGCGACAAGGTCTACGTACGCAAGGCGAAAGTAAAGGAAGCTAGGGTGGTAAAGCTCGCCCC
GGCGAACTTCAGCGTAAGCATAGATGAGGGCTTCATACCATATGCCAAGAAAAAGTTGATGGATAGGCCCGTAGTTGAGG
GGGATACGGTAATGATACCTATACTGGGTCAAACTATACCCTTCGTCGTCGTCAACACCAAGCCCAGCGGTGTAGTAAAA
ATAACGAAGAACACAAATATAATGATTCTAGAGAAGTATGTCGAACATGCTAGGGTACCCAAGGTAACTTGGGAGGACAT
AGGCGGCCTTGAAAACGTGGTCCGAAAGTTACGAGAACTAATAGAGCTACCTATGAAGTATCCTGAAATCTTCAAGAGGT
TGGGCATCGAGCCCCCGAAGGGAGTGCTCCTCTTCGGCCCTCCCGGTACCGGTAAGACCATGTTGGCCAAGGCCCTAGCC
AACGAGATAGATGCCCACTTCATACCCATCAACGGGCCAGAAATAATGAGCAAGTACTACGGCGAGAGCGAGCAGAGGCT
TAGGGAGATCTTCGAGGAGGCGCGCAAGAACGCTCCGAGCATAATATTCATAGACGAGATAGATGCAATTGCCCCCAAGA
GGGAGGAGGTAACCGGAGAGGTCGAGAAGAGGGTCGTCGCTCAGTTGTTGACCTTGATGGACGGCCTCCAAGAGAGGGGC
AGGGTTGTGGTAATAGGCGCGACCAACAGGCCGAACGCCATAGACCCCGCCCTCAGGAGGCCCGGGAGGTTAGAGGTCGA
GATAGAGATACCCTTACCTGACAAGAAGGGCAGGCTTGAGATACTGCAGATCCACACTAGAAACATGCCCTTAGCTGAGG
ACGTGGACTTAGAGAAGCTCGCCGAAATGACCCACGGTTACACCGGAGCGGACTTGGCAGCTCTCGTGAGGAGTGCTGCC
TTCTACGCGCTGAGGAGGTACCTGCCGGAGATAGACCTCGACAAGGGCGAGATACCCCCGGACCTGTTGGACAGGATGAA
GGTTACTATGGAGGATTTCATAAACGCGTACAAGGACATAGTACCCTCCGGCTTAAGAGAGATATACATAGAGACCCCCG
AAGTGCACTGGGAGGACGTCGGAGGCCTAAAGGAGGCGAAACAACAGCTGAGAGAGGCGGTCGAGTGGCCTCTAAAGTAT
CCGGAGGCCTTCCGCAGGCTCGGCATAGAGCCGCCGAAGGGGATACTCCTCTTCGGCCCTCCCGGTACCGGTAAGACCTT
GCTCGCCAAGGCGGCTGCCACGGAGAGCCAAGCGAACTTCATAGCGGTCAGGGGACCGGAGATCTTGAGCAAGTGGGTAG
GCGAGAGCGAGAAGGCGATAAGGGAGATCTTCCGCAAGGCCAGGCAAGCGGCCCCGACCATAGTGTTCTTCGACGAGATA
GACAGCATTGCCCCCGTTAGGGGGATGGACACGAGCACCCAAGTGACGGAAAGGATAGTGAGCCAGCTGCTAACCGAGAT
GGACGGCATAGAGAGGTTGGGCAACGTAGTTGTAATAGCTTCTACTAACAGGCCGGATATGGTCGACCCGGCGTTGCTGA
GGCCCGGGAGGTTCGACAAGCTGATCTACGTCCCGCCGCCGGACAAGGAGGCGAGGTTCCAAATACTAAAGATCCACACT
AGGAACATGCCGTTGGACATGGACGTAGACTTGTGGAGGCTGGCCGAGATGACTGAGGGCTACACCGGAGCGGACCTAGA
GGCCCTCTGTAGGGAGGCTGGCATGGAGGCAATGAGAGAAAACATCAATACTACTAAAGTATCAATGAGGCACTTCTTAA
ACGCCTTGAAGAGGGTGAAGCCGAGCATCACGCCGGAGATGTTAAAGTTCTACGAGACGTTCATGGAGAGGGCGAAGCAA
AGGGTCCAAGTCGCGAAGAAGGGCGGGCCTAGCATATACACGTGA

Upstream 100 bases:

>100_bases
CGAGGTCCTCCTCCGGTTTACCGAAGGGAAGGGCTGTATCTTGAAGGTCGGGGGTGTTGACCTAAAAACCTCGAATAGGA
CTGCGGAAGGGTCATAGGGA

Downstream 100 bases:

>100_bases
GGTGGGCTCGATGAGGAAGGGTCAGAGCGTTTGGAAATCCAGACCGCTTTACCTTTCCGTGTACAACATACTCAAGACCC
TTACCATACTACAAGGGGGC

Product: ATPase AAA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MAVPERVNPKGVELKVMEAKQKDVGHGRVRIDRMIMELIGVAPGDVVEIEGKRVTAAIALPAYPEDQGLDIIRMDGLIRK
NAGVTVGDKVYVRKAKVKEARVVKLAPANFSVSIDEGFIPYAKKKLMDRPVVEGDTVMIPILGQTIPFVVVNTKPSGVVK
ITKNTNIMILEKYVEHARVPKVTWEDIGGLENVVRKLRELIELPMKYPEIFKRLGIEPPKGVLLFGPPGTGKTMLAKALA
NEIDAHFIPINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERG
RVVVIGATNRPNAIDPALRRPGRLEVEIEIPLPDKKGRLEILQIHTRNMPLAEDVDLEKLAEMTHGYTGADLAALVRSAA
FYALRRYLPEIDLDKGEIPPDLLDRMKVTMEDFINAYKDIVPSGLREIYIETPEVHWEDVGGLKEAKQQLREAVEWPLKY
PEAFRRLGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPTIVFFDEI
DSIAPVRGMDTSTQVTERIVSQLLTEMDGIERLGNVVVIASTNRPDMVDPALLRPGRFDKLIYVPPPDKEARFQILKIHT
RNMPLDMDVDLWRLAEMTEGYTGADLEALCREAGMEAMRENINTTKVSMRHFLNALKRVKPSITPEMLKFYETFMERAKQ
RVQVAKKGGPSIYT

Sequences:

>Translated_734_residues
MAVPERVNPKGVELKVMEAKQKDVGHGRVRIDRMIMELIGVAPGDVVEIEGKRVTAAIALPAYPEDQGLDIIRMDGLIRK
NAGVTVGDKVYVRKAKVKEARVVKLAPANFSVSIDEGFIPYAKKKLMDRPVVEGDTVMIPILGQTIPFVVVNTKPSGVVK
ITKNTNIMILEKYVEHARVPKVTWEDIGGLENVVRKLRELIELPMKYPEIFKRLGIEPPKGVLLFGPPGTGKTMLAKALA
NEIDAHFIPINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERG
RVVVIGATNRPNAIDPALRRPGRLEVEIEIPLPDKKGRLEILQIHTRNMPLAEDVDLEKLAEMTHGYTGADLAALVRSAA
FYALRRYLPEIDLDKGEIPPDLLDRMKVTMEDFINAYKDIVPSGLREIYIETPEVHWEDVGGLKEAKQQLREAVEWPLKY
PEAFRRLGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPTIVFFDEI
DSIAPVRGMDTSTQVTERIVSQLLTEMDGIERLGNVVVIASTNRPDMVDPALLRPGRFDKLIYVPPPDKEARFQILKIHT
RNMPLDMDVDLWRLAEMTEGYTGADLEALCREAGMEAMRENINTTKVSMRHFLNALKRVKPSITPEMLKFYETFMERAKQ
RVQVAKKGGPSIYT
>Mature_733_residues
AVPERVNPKGVELKVMEAKQKDVGHGRVRIDRMIMELIGVAPGDVVEIEGKRVTAAIALPAYPEDQGLDIIRMDGLIRKN
AGVTVGDKVYVRKAKVKEARVVKLAPANFSVSIDEGFIPYAKKKLMDRPVVEGDTVMIPILGQTIPFVVVNTKPSGVVKI
TKNTNIMILEKYVEHARVPKVTWEDIGGLENVVRKLRELIELPMKYPEIFKRLGIEPPKGVLLFGPPGTGKTMLAKALAN
EIDAHFIPINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERGR
VVVIGATNRPNAIDPALRRPGRLEVEIEIPLPDKKGRLEILQIHTRNMPLAEDVDLEKLAEMTHGYTGADLAALVRSAAF
YALRRYLPEIDLDKGEIPPDLLDRMKVTMEDFINAYKDIVPSGLREIYIETPEVHWEDVGGLKEAKQQLREAVEWPLKYP
EAFRRLGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPTIVFFDEID
SIAPVRGMDTSTQVTERIVSQLLTEMDGIERLGNVVVIASTNRPDMVDPALLRPGRFDKLIYVPPPDKEARFQILKIHTR
NMPLDMDVDLWRLAEMTEGYTGADLEALCREAGMEAMRENINTTKVSMRHFLNALKRVKPSITPEMLKFYETFMERAKQR
VQVAKKGGPSIYT

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=719, Percent_Identity=44.923504867872, Blast_Score=630, Evalue=1e-180,
Organism=Homo sapiens, GI157671927, Length=579, Percent_Identity=50.9499136442142, Blast_Score=589, Evalue=1e-168,
Organism=Homo sapiens, GI45643125, Length=597, Percent_Identity=43.3835845896147, Blast_Score=481, Evalue=1e-135,
Organism=Homo sapiens, GI45643123, Length=597, Percent_Identity=43.3835845896147, Blast_Score=481, Evalue=1e-135,
Organism=Homo sapiens, GI229577436, Length=757, Percent_Identity=39.6301188903567, Blast_Score=470, Evalue=1e-132,
Organism=Homo sapiens, GI4505725, Length=479, Percent_Identity=38.4133611691023, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI194018488, Length=515, Percent_Identity=35.1456310679612, Blast_Score=286, Evalue=7e-77,
Organism=Homo sapiens, GI153792536, Length=273, Percent_Identity=46.1538461538462, Blast_Score=246, Evalue=6e-65,
Organism=Homo sapiens, GI24497618, Length=273, Percent_Identity=45.0549450549451, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI24430151, Length=297, Percent_Identity=43.4343434343434, Blast_Score=233, Evalue=5e-61,
Organism=Homo sapiens, GI24497435, Length=235, Percent_Identity=47.2340425531915, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI4506209, Length=269, Percent_Identity=45.724907063197, Blast_Score=229, Evalue=9e-60,
Organism=Homo sapiens, GI195539395, Length=250, Percent_Identity=44.4, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI5729991, Length=264, Percent_Identity=42.8030303030303, Blast_Score=216, Evalue=8e-56,
Organism=Homo sapiens, GI24430155, Length=264, Percent_Identity=42.8030303030303, Blast_Score=216, Evalue=9e-56,
Organism=Homo sapiens, GI89064750, Length=264, Percent_Identity=42.8030303030303, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI156564401, Length=391, Percent_Identity=38.3631713554987, Blast_Score=214, Evalue=3e-55,
Organism=Homo sapiens, GI21361144, Length=271, Percent_Identity=42.8044280442804, Blast_Score=212, Evalue=1e-54,
Organism=Homo sapiens, GI14149767, Length=301, Percent_Identity=42.1926910299003, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI62177112, Length=301, Percent_Identity=42.1926910299003, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI300192933, Length=252, Percent_Identity=44.047619047619, Blast_Score=206, Evalue=8e-53,
Organism=Homo sapiens, GI5901990, Length=301, Percent_Identity=40.8637873754153, Blast_Score=205, Evalue=2e-52,
Organism=Homo sapiens, GI4507173, Length=250, Percent_Identity=43.2, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI226371754, Length=329, Percent_Identity=36.1702127659575, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI31742536, Length=283, Percent_Identity=36.7491166077738, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI112789543, Length=283, Percent_Identity=36.7491166077738, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI7019569, Length=263, Percent_Identity=39.1634980988593, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI310125280, Length=256, Percent_Identity=43.75, Blast_Score=186, Evalue=9e-47,
Organism=Homo sapiens, GI310125282, Length=256, Percent_Identity=43.75, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI21327685, Length=235, Percent_Identity=42.1276595744681, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI7657689, Length=235, Percent_Identity=42.1276595744681, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI40806170, Length=484, Percent_Identity=30.7851239669421, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI11875211, Length=306, Percent_Identity=36.9281045751634, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI17865802, Length=250, Percent_Identity=40, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI31377644, Length=246, Percent_Identity=40.650406504065, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI64084766, Length=286, Percent_Identity=33.5664335664336, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=47.8260869565217, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI116292174, Length=266, Percent_Identity=28.9473684210526, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI11321607, Length=160, Percent_Identity=32.5, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI75677353, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI40255052, Length=252, Percent_Identity=24.2063492063492, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1789568, Length=245, Percent_Identity=45.3061224489796, Blast_Score=204, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=729, Percent_Identity=43.758573388203, Blast_Score=625, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17531535, Length=746, Percent_Identity=42.627345844504, Blast_Score=613, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17537217, Length=604, Percent_Identity=40.5629139072848, Blast_Score=419, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17508053, Length=533, Percent_Identity=38.4615384615385, Blast_Score=352, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17562804, Length=496, Percent_Identity=33.6693548387097, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI25153574, Length=480, Percent_Identity=33.5416666666667, Blast_Score=239, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17563250, Length=297, Percent_Identity=41.7508417508418, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI193206116, Length=279, Percent_Identity=44.0860215053763, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI133931034, Length=279, Percent_Identity=44.0860215053763, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI193206114, Length=279, Percent_Identity=44.0860215053763, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17554786, Length=230, Percent_Identity=47.8260869565217, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI71987364, Length=227, Percent_Identity=48.0176211453744, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71987372, Length=227, Percent_Identity=48.0176211453744, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI25144278, Length=235, Percent_Identity=47.2340425531915, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI25144281, Length=235, Percent_Identity=47.2340425531915, Blast_Score=224, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17563248, Length=268, Percent_Identity=43.2835820895522, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193209502, Length=224, Percent_Identity=48.6607142857143, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17554784, Length=285, Percent_Identity=41.0526315789474, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17505546, Length=231, Percent_Identity=45.021645021645, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17508701, Length=252, Percent_Identity=38.8888888888889, Blast_Score=209, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI133901662, Length=382, Percent_Identity=35.8638743455497, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI133901658, Length=382, Percent_Identity=35.8638743455497, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71994521, Length=263, Percent_Identity=43.3460076045627, Blast_Score=188, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI25146157, Length=299, Percent_Identity=38.1270903010033, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI86561515, Length=236, Percent_Identity=41.5254237288136, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554264, Length=237, Percent_Identity=41.7721518987342, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17560432, Length=286, Percent_Identity=37.7622377622378, Blast_Score=169, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI115534323, Length=256, Percent_Identity=40.625, Blast_Score=169, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17541224, Length=217, Percent_Identity=38.2488479262673, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17541226, Length=217, Percent_Identity=38.2488479262673, Blast_Score=165, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17508421, Length=289, Percent_Identity=38.0622837370242, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32563584, Length=291, Percent_Identity=37.8006872852234, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=128, Percent_Identity=38.28125, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32566590, Length=128, Percent_Identity=38.28125, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17533043, Length=185, Percent_Identity=30.2702702702703, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320077, Length=737, Percent_Identity=44.0976933514247, Blast_Score=618, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6323429, Length=544, Percent_Identity=51.6544117647059, Blast_Score=563, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322994, Length=621, Percent_Identity=39.2914653784219, Blast_Score=445, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6324000, Length=587, Percent_Identity=32.3679727427598, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321709, Length=275, Percent_Identity=48, Blast_Score=257, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6322651, Length=489, Percent_Identity=34.560327198364, Blast_Score=256, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6321390, Length=235, Percent_Identity=46.3829787234043, Blast_Score=230, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=48.3739837398374, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320197, Length=273, Percent_Identity=43.2234432234432, Blast_Score=218, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6319554, Length=410, Percent_Identity=35.609756097561, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6322704, Length=251, Percent_Identity=43.8247011952191, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6320602, Length=264, Percent_Identity=43.5606060606061, Blast_Score=210, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=283, Percent_Identity=40.9893992932862, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6325183, Length=297, Percent_Identity=38.047138047138, Blast_Score=199, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6320854, Length=256, Percent_Identity=41.796875, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6325281, Length=269, Percent_Identity=39.7769516728625, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323736, Length=251, Percent_Identity=41.8326693227092, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6325431, Length=238, Percent_Identity=41.5966386554622, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321465, Length=232, Percent_Identity=43.5344827586207, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320887, Length=305, Percent_Identity=36.0655737704918, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI9755327, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320583, Length=151, Percent_Identity=31.7880794701987, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17137560, Length=742, Percent_Identity=43.2614555256065, Blast_Score=615, Evalue=1e-176,
Organism=Drosophila melanogaster, GI161076486, Length=742, Percent_Identity=43.2614555256065, Blast_Score=614, Evalue=1e-176,
Organism=Drosophila melanogaster, GI161076488, Length=720, Percent_Identity=43.75, Blast_Score=611, Evalue=1e-175,
Organism=Drosophila melanogaster, GI19921202, Length=596, Percent_Identity=40.4362416107383, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI45552965, Length=299, Percent_Identity=46.4882943143813, Blast_Score=282, Evalue=6e-76,
Organism=Drosophila melanogaster, GI281365776, Length=299, Percent_Identity=46.4882943143813, Blast_Score=282, Evalue=7e-76,
Organism=Drosophila melanogaster, GI24660075, Length=299, Percent_Identity=46.4882943143813, Blast_Score=282, Evalue=7e-76,
Organism=Drosophila melanogaster, GI21355121, Length=517, Percent_Identity=33.2688588007737, Blast_Score=281, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24656825, Length=519, Percent_Identity=33.140655105973, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24656820, Length=538, Percent_Identity=31.7843866171004, Blast_Score=266, Evalue=6e-71,
Organism=Drosophila melanogaster, GI281363136, Length=606, Percent_Identity=30.5280528052805, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI78707192, Length=606, Percent_Identity=30.5280528052805, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI19920408, Length=280, Percent_Identity=43.2142857142857, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24652279, Length=258, Percent_Identity=44.5736434108527, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24651451, Length=232, Percent_Identity=48.7068965517241, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24649446, Length=297, Percent_Identity=43.0976430976431, Blast_Score=231, Evalue=2e-60,
Organism=Drosophila melanogaster, GI17137738, Length=267, Percent_Identity=44.1947565543071, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI18860063, Length=236, Percent_Identity=46.6101694915254, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24640100, Length=235, Percent_Identity=47.2340425531915, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281361487, Length=236, Percent_Identity=45.7627118644068, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI17738151, Length=252, Percent_Identity=41.2698412698413, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24663015, Length=268, Percent_Identity=43.2835820895522, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24665814, Length=249, Percent_Identity=44.578313253012, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI28574878, Length=249, Percent_Identity=44.578313253012, Blast_Score=205, Evalue=9e-53,
Organism=Drosophila melanogaster, GI28573010, Length=388, Percent_Identity=35.5670103092784, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17864540, Length=383, Percent_Identity=36.2924281984334, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24658770, Length=253, Percent_Identity=43.4782608695652, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24644145, Length=290, Percent_Identity=40.6896551724138, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI18859657, Length=239, Percent_Identity=45.6066945606695, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24639391, Length=252, Percent_Identity=40.8730158730159, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI281360146, Length=291, Percent_Identity=36.426116838488, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281360138, Length=291, Percent_Identity=36.426116838488, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281360142, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357333, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28571849, Length=289, Percent_Identity=39.4463667820069, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28571847, Length=289, Percent_Identity=39.4463667820069, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281360144, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281360140, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24581396, Length=275, Percent_Identity=38.5454545454545, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281360136, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24644411, Length=291, Percent_Identity=36.426116838488, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI20129423, Length=291, Percent_Identity=34.7079037800687, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI20129529, Length=239, Percent_Identity=38.0753138075314, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24639486, Length=236, Percent_Identity=36.864406779661, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=43.3734939759036, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28573181, Length=165, Percent_Identity=29.0909090909091, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 82251; Mature: 82120

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MAVPERVNPKGVELKVMEAKQKDVGHGRVRIDRMIMELIGVAPGDVVEIEGKRVTAAIAL
CCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEE
PAYPEDQGLDIIRMDGLIRKNAGVTVGDKVYVRKAKVKEARVVKLAPANFSVSIDEGFIP
CCCCCCCCCCEEEECCEEECCCCCEECCCEEEEHHHHCCCEEEEEECCCEEEEECCCCCC
YAKKKLMDRPVVEGDTVMIPILGQTIPFVVVNTKPSGVVKITKNTNIMILEKYVEHARVP
HHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEHHHHHHCCCC
KVTWEDIGGLENVVRKLRELIELPMKYPEIFKRLGIEPPKGVLLFGPPGTGKTMLAKALA
CCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHH
NEIDAHFIPINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGE
HHCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
VEKRVVAQLLTLMDGLQERGRVVVIGATNRPNAIDPALRRPGRLEVEIEIPLPDKKGRLE
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCEE
ILQIHTRNMPLAEDVDLEKLAEMTHGYTGADLAALVRSAAFYALRRYLPEIDLDKGEIPP
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLDRMKVTMEDFINAYKDIVPSGLREIYIETPEVHWEDVGGLKEAKQQLREAVEWPLKY
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHCCCHHHHHHHHHHHHHCCCCC
PEAFRRLGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAI
HHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCHHHHH
REIFRKARQAAPTIVFFDEIDSIAPVRGMDTSTQVTERIVSQLLTEMDGIERLGNVVVIA
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
STNRPDMVDPALLRPGRFDKLIYVPPPDKEARFQILKIHTRNMPLDMDVDLWRLAEMTEG
ECCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCC
YTGADLEALCREAGMEAMRENINTTKVSMRHFLNALKRVKPSITPEMLKFYETFMERAKQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RVQVAKKGGPSIYT
HHHHHHCCCCCCCC
>Mature Secondary Structure 
AVPERVNPKGVELKVMEAKQKDVGHGRVRIDRMIMELIGVAPGDVVEIEGKRVTAAIAL
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEE
PAYPEDQGLDIIRMDGLIRKNAGVTVGDKVYVRKAKVKEARVVKLAPANFSVSIDEGFIP
CCCCCCCCCCEEEECCEEECCCCCEECCCEEEEHHHHCCCEEEEEECCCEEEEECCCCCC
YAKKKLMDRPVVEGDTVMIPILGQTIPFVVVNTKPSGVVKITKNTNIMILEKYVEHARVP
HHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEHHHHHHCCCC
KVTWEDIGGLENVVRKLRELIELPMKYPEIFKRLGIEPPKGVLLFGPPGTGKTMLAKALA
CCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHH
NEIDAHFIPINGPEIMSKYYGESEQRLREIFEEARKNAPSIIFIDEIDAIAPKREEVTGE
HHCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
VEKRVVAQLLTLMDGLQERGRVVVIGATNRPNAIDPALRRPGRLEVEIEIPLPDKKGRLE
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCEE
ILQIHTRNMPLAEDVDLEKLAEMTHGYTGADLAALVRSAAFYALRRYLPEIDLDKGEIPP
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLDRMKVTMEDFINAYKDIVPSGLREIYIETPEVHWEDVGGLKEAKQQLREAVEWPLKY
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHCCCHHHHHHHHHHHHHCCCCC
PEAFRRLGIEPPKGILLFGPPGTGKTLLAKAAATESQANFIAVRGPEILSKWVGESEKAI
HHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCHHHHH
REIFRKARQAAPTIVFFDEIDSIAPVRGMDTSTQVTERIVSQLLTEMDGIERLGNVVVIA
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
STNRPDMVDPALLRPGRFDKLIYVPPPDKEARFQILKIHTRNMPLDMDVDLWRLAEMTEG
ECCCCCCCCHHHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCC
YTGADLEALCREAGMEAMRENINTTKVSMRHFLNALKRVKPSITPEMLKFYETFMERAKQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RVQVAKKGGPSIYT
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]