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The map label for this gene is ygbD [C]

Identifier: 156937464

GI number: 156937464

Start: 603471

End: 604823

Strand: Reverse

Name: ygbD [C]

Synonym: Igni_0671

Alternate gene names: 156937464

Gene position: 604823-603471 (Counterclockwise)

Preceding gene: 156937465

Following gene: 156937463

Centisome position: 46.61

GC content: 61.86

Gene sequence:

>1353_bases
GTGGGCCCGGTGCCCCACGTGGAGGTCGTAGTCGTAGGCGGCGGCGCCGCGGGCATGAGCGCTGCTTCCCGCGTGAAAAG
GATACACAAGGACTGGACGGTTAGGGTTTTCGAGGCCTCAGGTTACGTCTCCTACGCCCCTTGCGGCCTCCCGTACTTCA
TCGTGGGCAAGGTAAAGGAACCCGACGACTTGGTTTACTATCCTGTCGAAGTGTTCAGGGAAAAGAGGGGTATAGACGTA
CACACGCACGCTAAGGTCGTGGACGCCGATTACCACAAGAGAACGGTAACCGTCATTGAGAACGGGGAAAAGAAGGAGTA
CAAGTGGGACAAGCTCATATTGGCCACCGGGGCGCGACCCAAGTCGTTGGGCGTCGAAGGCGAGGACCTCAGAGGAGTCA
TAAAGCTTCACACGGTAGAGAGCGGGATAGCCGCTAGGGAGGAGCTGAAGGACGCGAAGGAGGTAGTGGTGGTGGGCGCG
GGGTTCACCGGCGTAGAGGTCGCTGCGGAGCTGAGGGACTCCGAGCGCGAGGTGCACTTGGTGGTCCGCTCGCGCGCCCT
TCGCAAGAGCTTGGACCCGGAGATGAGCGAGCTCGTGGAGGAGCACCTTAAGAACGTAGGGATAAGGCTCCACAAGGGCG
TAACTGTAACCAAGATACTCGGGAAGGACCGGGTCGAAGGCGTGGAGCTGAGCGACGGAGAGGTGATAAAGGCTCAAGCG
GTAGTGGTGGCAGTGGGGGTAGAGCCCAACGCAGAGCTCGCTAAGAGGTTGGGCGTGAAGTTGGGTAAGTTCGGGGGAAT
CAAAGTGAACGAGTACATGGAGACCAACTTGCCCGACGTCTACGCCGCCGGGGACGTGGCGGAGAGCTGGCTCGTCCACA
CGGGGACCGAGGCTTGGTGTCCCTTCGCTCCCCCGGCCAACAAGATGGGGCTCGTCGCCGGCCTCAGCGCCAGCGGCAAA
AGGGTCCCGTTTCCGGGAGTGGCTTGTACCGGGATCACGGTCGCCTCGGGCCTGGAGATCGGCCGGACGGGCCTGACCGA
GGAGGAGGCGAAGGCCTTAGGCTTTAAGGTTAAGTCCTCGTTCGTGAAGGCTAGGACGAGGGCCCACTACTACCCCGGCT
CCCAGTTCACCCACGTCAAGCTGGTGGCCGCCGAGGACGGCACCGTGTTGGGCGTTCAAGTGGTGGGCCCAGAGGGGGTC
AAGGGGAGGGTGGACGCCGTTGCGACGTTGCTAACTAAGAGGGGGACCGTTAGGGACTTGTTCTTCTCTGACATAGGCTA
CGTCCCTCCCTTGGCCCCCGTGTGGGACCCCTTGGTCACCGCGGCGAGGCTCTTGTATTCGGAACTGCGCTAA

Upstream 100 bases:

>100_bases
GATGCTGTACTTAGCCAAGGTCATGGGCTCTTGCTTGAGACAGAAGATGGAGCAATCCTAACCGTTTAGTAAAAACGCGT
AAATTATTTTCCGCGCGCTC

Downstream 100 bases:

>100_bases
TCTCTTTATCCAATTTTTGCATACCAGAGCAACTCCCTATCTTAAAACCCGCTACCCCGCCGTTGTCATCGAGAGAGTGA
GAACATGAAGATCGCGAGGA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MGPVPHVEVVVVGGGAAGMSAASRVKRIHKDWTVRVFEASGYVSYAPCGLPYFIVGKVKEPDDLVYYPVEVFREKRGIDV
HTHAKVVDADYHKRTVTVIENGEKKEYKWDKLILATGARPKSLGVEGEDLRGVIKLHTVESGIAAREELKDAKEVVVVGA
GFTGVEVAAELRDSEREVHLVVRSRALRKSLDPEMSELVEEHLKNVGIRLHKGVTVTKILGKDRVEGVELSDGEVIKAQA
VVVAVGVEPNAELAKRLGVKLGKFGGIKVNEYMETNLPDVYAAGDVAESWLVHTGTEAWCPFAPPANKMGLVAGLSASGK
RVPFPGVACTGITVASGLEIGRTGLTEEEAKALGFKVKSSFVKARTRAHYYPGSQFTHVKLVAAEDGTVLGVQVVGPEGV
KGRVDAVATLLTKRGTVRDLFFSDIGYVPPLAPVWDPLVTAARLLYSELR

Sequences:

>Translated_450_residues
MGPVPHVEVVVVGGGAAGMSAASRVKRIHKDWTVRVFEASGYVSYAPCGLPYFIVGKVKEPDDLVYYPVEVFREKRGIDV
HTHAKVVDADYHKRTVTVIENGEKKEYKWDKLILATGARPKSLGVEGEDLRGVIKLHTVESGIAAREELKDAKEVVVVGA
GFTGVEVAAELRDSEREVHLVVRSRALRKSLDPEMSELVEEHLKNVGIRLHKGVTVTKILGKDRVEGVELSDGEVIKAQA
VVVAVGVEPNAELAKRLGVKLGKFGGIKVNEYMETNLPDVYAAGDVAESWLVHTGTEAWCPFAPPANKMGLVAGLSASGK
RVPFPGVACTGITVASGLEIGRTGLTEEEAKALGFKVKSSFVKARTRAHYYPGSQFTHVKLVAAEDGTVLGVQVVGPEGV
KGRVDAVATLLTKRGTVRDLFFSDIGYVPPLAPVWDPLVTAARLLYSELR
>Mature_449_residues
GPVPHVEVVVVGGGAAGMSAASRVKRIHKDWTVRVFEASGYVSYAPCGLPYFIVGKVKEPDDLVYYPVEVFREKRGIDVH
THAKVVDADYHKRTVTVIENGEKKEYKWDKLILATGARPKSLGVEGEDLRGVIKLHTVESGIAAREELKDAKEVVVVGAG
FTGVEVAAELRDSEREVHLVVRSRALRKSLDPEMSELVEEHLKNVGIRLHKGVTVTKILGKDRVEGVELSDGEVIKAQAV
VVAVGVEPNAELAKRLGVKLGKFGGIKVNEYMETNLPDVYAAGDVAESWLVHTGTEAWCPFAPPANKMGLVAGLSASGKR
VPFPGVACTGITVASGLEIGRTGLTEEEAKALGFKVKSSFVKARTRAHYYPGSQFTHVKLVAAEDGTVLGVQVVGPEGVK
GRVDAVATLLTKRGTVRDLFFSDIGYVPPLAPVWDPLVTAARLLYSELR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=281, Percent_Identity=32.0284697508897, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI65787454, Length=281, Percent_Identity=32.0284697508897, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI21389617, Length=281, Percent_Identity=32.0284697508897, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI291045266, Length=389, Percent_Identity=25.9640102827763, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33519430, Length=395, Percent_Identity=24.8101265822785, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI33519428, Length=395, Percent_Identity=24.8101265822785, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI33519426, Length=395, Percent_Identity=24.8101265822785, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI148277065, Length=395, Percent_Identity=24.8101265822785, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI148277071, Length=395, Percent_Identity=24.8101265822785, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI22202629, Length=232, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4757732, Length=232, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI291045268, Length=233, Percent_Identity=29.1845493562232, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789065, Length=326, Percent_Identity=25.1533742331288, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789765, Length=396, Percent_Identity=25.2525252525253, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788892, Length=282, Percent_Identity=25.531914893617, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789915, Length=230, Percent_Identity=31.304347826087, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=28.8888888888889, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082354, Length=180, Percent_Identity=30, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17557007, Length=352, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71983429, Length=263, Percent_Identity=30.0380228136882, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983419, Length=263, Percent_Identity=30.0380228136882, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325166, Length=236, Percent_Identity=25.8474576271186, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585130, Length=272, Percent_Identity=25.3676470588235, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281359715, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359713, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639250, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18543267, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639252, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639257, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581020, Length=320, Percent_Identity=24.6875, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573993, Length=320, Percent_Identity=24.6875, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48500; Mature: 48369

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVPHVEVVVVGGGAAGMSAASRVKRIHKDWTVRVFEASGYVSYAPCGLPYFIVGKVKE
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCEEEEECCCC
PDDLVYYPVEVFREKRGIDVHTHAKVVDADYHKRTVTVIENGEKKEYKWDKLILATGARP
CCCEEEECHHHHHHHCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCEEEEEEEECCCC
KSLGVEGEDLRGVIKLHTVESGIAAREELKDAKEVVVVGAGFTGVEVAAELRDSEREVHL
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEH
VVRSRALRKSLDPEMSELVEEHLKNVGIRLHKGVTVTKILGKDRVEGVELSDGEVIKAQA
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCCCCCEECCCCCEEEEEE
VVVAVGVEPNAELAKRLGVKLGKFGGIKVNEYMETNLPDVYAAGDVAESWLVHTGTEAWC
EEEEEECCCCHHHHHHHCCEECCCCCEEEHHHHHCCCCCEEECCHHHHHHEEECCCCCCC
PFAPPANKMGLVAGLSASGKRVPFPGVACTGITVASGLEIGRTGLTEEEAKALGFKVKSS
CCCCCCCCCEEEEECCCCCCCCCCCCCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FVKARTRAHYYPGSQFTHVKLVAAEDGTVLGVQVVGPEGVKGRVDAVATLLTKRGTVRDL
HHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHH
FFSDIGYVPPLAPVWDPLVTAARLLYSELR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GPVPHVEVVVVGGGAAGMSAASRVKRIHKDWTVRVFEASGYVSYAPCGLPYFIVGKVKE
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCEEEEECCCC
PDDLVYYPVEVFREKRGIDVHTHAKVVDADYHKRTVTVIENGEKKEYKWDKLILATGARP
CCCEEEECHHHHHHHCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCEEEEEEEECCCC
KSLGVEGEDLRGVIKLHTVESGIAAREELKDAKEVVVVGAGFTGVEVAAELRDSEREVHL
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEH
VVRSRALRKSLDPEMSELVEEHLKNVGIRLHKGVTVTKILGKDRVEGVELSDGEVIKAQA
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCCCCCEECCCCCEEEEEE
VVVAVGVEPNAELAKRLGVKLGKFGGIKVNEYMETNLPDVYAAGDVAESWLVHTGTEAWC
EEEEEECCCCHHHHHHHCCEECCCCCEEEHHHHHCCCCCEEECCHHHHHHEEECCCCCCC
PFAPPANKMGLVAGLSASGKRVPFPGVACTGITVASGLEIGRTGLTEEEAKALGFKVKSS
CCCCCCCCCEEEEECCCCCCCCCCCCCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FVKARTRAHYYPGSQFTHVKLVAAEDGTVLGVQVVGPEGVKGRVDAVATLLTKRGTVRDL
HHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHH
FFSDIGYVPPLAPVWDPLVTAARLLYSELR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA