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The map label for this gene is nagD [H]

Identifier: 156937442

GI number: 156937442

Start: 585589

End: 586329

Strand: Direct

Name: nagD [H]

Synonym: Igni_0649

Alternate gene names: 156937442

Gene position: 585589-586329 (Clockwise)

Preceding gene: 156937439

Following gene: 156937446

Centisome position: 45.13

GC content: 57.89

Gene sequence:

>741_bases
TTGGGGAGCGCCTTGAGGTGGATAATAGACCTCGACGGCGTGGTGTGGAAGGGAAAGGAAATAATCTGGGAAAACGTGGA
CGCGATAAAAAAGTTGGAAGGGAAGAAAGTATTCCTAACGAACAAGGCTACCTCGCGCTGGGAAGTTTCTAGGAGGCTAA
AGGAGATAGGGTTGGAAGGGGAGGTAGTTACCTCTGCCTACATAGCCTCCCAGTTCCTCAAGAAGAGGGGCGTGGAATCC
GCCTTCGCGGTGGGACCTTCCGGACTGGCGGAAGAGCTGGTTATGGCAGGAATACACTTGACCGAAGACGAAGACCTCGC
GCAAGCGGTGGTGGCGGGCTTGGACGCGTTCTTGACGTATGACAAGGTCGCTAGGGCAGCATCCATGATAAGGAAGGGGG
CTCTATTCGTAGCCACCAACACCGACAAGACCTACCCCACCGAGAGGGGGCTCATGCCGGGCGCGGGGAGCGTGGTGGAG
GCGATAAGGGTGGCCAGCGGGAAGGAGCCAGTAGTGGTGGGGAAGCCCAGCAGACACGCCTTCGAGGTGGCCAGCGGCGG
CGAGAGGGACGTGATAGTAATAGGGGATAAGATGGAAACCGACATGAAGATGGCGCTAGAAAACGGGGCCAGGGGAATCT
TGGTGCTGACCGGCGTGACCCGGGAGCCTCCCAAGGAGGTCCCTCAAGGAGTAACGGTCGTGAAGACGCTGAAGGAAGTT
TTGGGGGATGAGACCGGATAG

Upstream 100 bases:

>100_bases
CACTACCTTTATCCAGCCCATCTTGGCGAAGTACTTTACTGGAGCGTTCGGGTCTATCAAGGCTCTCTCGAGAGTTAAGA
CCTTTAACAAATATTTTAGT

Downstream 100 bases:

>100_bases
GCGCTCTCATCGAGAGCTCTGCGGCTCCCTCCGCGCCCGACACCCGGGCGCTAACCGCTCTGCTCTTGTCTCTGATAAGC
TTGACGCCTCTTTATCGGAC

Product: HAD family hydrolase

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MGSALRWIIDLDGVVWKGKEIIWENVDAIKKLEGKKVFLTNKATSRWEVSRRLKEIGLEGEVVTSAYIASQFLKKRGVES
AFAVGPSGLAEELVMAGIHLTEDEDLAQAVVAGLDAFLTYDKVARAASMIRKGALFVATNTDKTYPTERGLMPGAGSVVE
AIRVASGKEPVVVGKPSRHAFEVASGGERDVIVIGDKMETDMKMALENGARGILVLTGVTREPPKEVPQGVTVVKTLKEV
LGDETG

Sequences:

>Translated_246_residues
MGSALRWIIDLDGVVWKGKEIIWENVDAIKKLEGKKVFLTNKATSRWEVSRRLKEIGLEGEVVTSAYIASQFLKKRGVES
AFAVGPSGLAEELVMAGIHLTEDEDLAQAVVAGLDAFLTYDKVARAASMIRKGALFVATNTDKTYPTERGLMPGAGSVVE
AIRVASGKEPVVVGKPSRHAFEVASGGERDVIVIGDKMETDMKMALENGARGILVLTGVTREPPKEVPQGVTVVKTLKEV
LGDETG
>Mature_245_residues
GSALRWIIDLDGVVWKGKEIIWENVDAIKKLEGKKVFLTNKATSRWEVSRRLKEIGLEGEVVTSAYIASQFLKKRGVESA
FAVGPSGLAEELVMAGIHLTEDEDLAQAVVAGLDAFLTYDKVARAASMIRKGALFVATNTDKTYPTERGLMPGAGSVVEA
IRVASGKEPVVVGKPSRHAFEVASGGERDVIVIGDKMETDMKMALENGARGILVLTGVTREPPKEVPQGVTVVKTLKEVL
GDETG

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=248, Percent_Identity=31.4516129032258, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI108796653, Length=255, Percent_Identity=29.8039215686275, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI14149777, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786890, Length=225, Percent_Identity=28.8888888888889, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560956, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17558880, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562458, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193210059, Length=255, Percent_Identity=24.7058823529412, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563050, Length=245, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319965, Length=236, Percent_Identity=28.8135593220339, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24666141, Length=247, Percent_Identity=30.3643724696356, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24656326, Length=254, Percent_Identity=29.1338582677165, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24656330, Length=256, Percent_Identity=27.734375, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19920940, Length=248, Percent_Identity=27.0161290322581, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 26421; Mature: 26290

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSALRWIIDLDGVVWKGKEIIWENVDAIKKLEGKKVFLTNKATSRWEVSRRLKEIGLEG
CCCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCC
EVVTSAYIASQFLKKRGVESAFAVGPSGLAEELVMAGIHLTEDEDLAQAVVAGLDAFLTY
HHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DKVARAASMIRKGALFVATNTDKTYPTERGLMPGAGSVVEAIRVASGKEPVVVGKPSRHA
HHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCE
FEVASGGERDVIVIGDKMETDMKMALENGARGILVLTGVTREPPKEVPQGVTVVKTLKEV
EECCCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHH
LGDETG
HCCCCC
>Mature Secondary Structure 
GSALRWIIDLDGVVWKGKEIIWENVDAIKKLEGKKVFLTNKATSRWEVSRRLKEIGLEG
CCCEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCC
EVVTSAYIASQFLKKRGVESAFAVGPSGLAEELVMAGIHLTEDEDLAQAVVAGLDAFLTY
HHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DKVARAASMIRKGALFVATNTDKTYPTERGLMPGAGSVVEAIRVASGKEPVVVGKPSRHA
HHHHHHHHHHHCCCEEEEECCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCE
FEVASGGERDVIVIGDKMETDMKMALENGARGILVLTGVTREPPKEVPQGVTVVKTLKEV
EECCCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHH
LGDETG
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA