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The map label for this gene is argB

Identifier: 156937414

GI number: 156937414

Start: 555567

End: 556361

Strand: Reverse

Name: argB

Synonym: Igni_0621

Alternate gene names: 156937414

Gene position: 556361-555567 (Counterclockwise)

Preceding gene: 156937419

Following gene: 156937413

Centisome position: 42.88

GC content: 57.36

Gene sequence:

>795_bases
ATGATAGTAGTAAAAGCCGGTGGCAGGACGTTGTTGAACAACATGGATGAGATAGTCAAGAGCATTTCTCGGTTAGAGAA
GGCGGTGTTCGTGCACGGAGGGGGAGACCTAGTGGACGAGTGGGAGAGGAAAATGGGGATGGAACCCCAGTTCAAGGTCT
CCGCCTCCGGGATAAAATTTAGGTACACGGACGAGAAGGAGCTCGAAGTGTTCGTAGCGGTCCTCGGGGGTTTGTTGAAT
AAGAAGATAGTCGCCTCCTTCGCCTCCTACGGGAGGGGCGCGGTAGGGCTGACCGGAGCCGACGGGCCGAGCGTGATAGC
GGAGAGGAAGAAGAAAGTTATCGTCCAAGAAAAGGTGGGCGAGAGGCTCGTAAAGAGGGCCATCGCCGGCGGCTATACGG
GCAAGATAAAGGAGGTGAAAACGGACCTAATCAAGGCCTTAGTGGAGAGGGGCTTGGTACCGGTAGTCGCTCCCATAGCG
CTGAGCCCCGAGGGCGAGCTCTTGAACGTAAACGGGGACCAGATGGCGGCTGAACTGGCTAAGGCGTTGTCCGCGGAGTA
CCTCGTACTCTTGACCGACGTTCCCGGAGTTCTGATGGACGGGAAGGTGGTACCCGAGATAAAGTCCTCAGAGGCGGAAG
AGGTGGCCAAGAAGGTGGGCCCTGGGATGAACATCAAAATAATAATGGCGGGAAGGGTCGCCTCCGGGGGGACCAAAGTG
GTCATATGCGACGGCACCGTCCCCGACCCCCTGAAGTGTTTGGAAGAGAGGAGCGGGACGTGGGTGGTGCCTTGA

Upstream 100 bases:

>100_bases
AGCCTTTCGTGAAGGCGACTTGCTCGTCTGGAGCAACTAATAAACTTGGACGCAAGCGTTGAAGACCGTGCCCTCCCCCT
CCCCTTCGGTGGCCTAGCCA

Downstream 100 bases:

>100_bases
AGGCCTCGGGTCCCGAGGTCTGAGCGCTCACCGCTCGACGTAGCCCACGCTCCTCATCGGCGATAAAACCTCTTCTCTTT
CCTATCGACGCGGGTAAGAG

Product: N2-acetyl-L-aminoadipate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate/N-acetyl-L-aminoadipate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MIVVKAGGRTLLNNMDEIVKSISRLEKAVFVHGGGDLVDEWERKMGMEPQFKVSASGIKFRYTDEKELEVFVAVLGGLLN
KKIVASFASYGRGAVGLTGADGPSVIAERKKKVIVQEKVGERLVKRAIAGGYTGKIKEVKTDLIKALVERGLVPVVAPIA
LSPEGELLNVNGDQMAAELAKALSAEYLVLLTDVPGVLMDGKVVPEIKSSEAEEVAKKVGPGMNIKIIMAGRVASGGTKV
VICDGTVPDPLKCLEERSGTWVVP

Sequences:

>Translated_264_residues
MIVVKAGGRTLLNNMDEIVKSISRLEKAVFVHGGGDLVDEWERKMGMEPQFKVSASGIKFRYTDEKELEVFVAVLGGLLN
KKIVASFASYGRGAVGLTGADGPSVIAERKKKVIVQEKVGERLVKRAIAGGYTGKIKEVKTDLIKALVERGLVPVVAPIA
LSPEGELLNVNGDQMAAELAKALSAEYLVLLTDVPGVLMDGKVVPEIKSSEAEEVAKKVGPGMNIKIIMAGRVASGGTKV
VICDGTVPDPLKCLEERSGTWVVP
>Mature_264_residues
MIVVKAGGRTLLNNMDEIVKSISRLEKAVFVHGGGDLVDEWERKMGMEPQFKVSASGIKFRYTDEKELEVFVAVLGGLLN
KKIVASFASYGRGAVGLTGADGPSVIAERKKKVIVQEKVGERLVKRAIAGGYTGKIKEVKTDLIKALVERGLVPVVAPIA
LSPEGELLNVNGDQMAAELAKALSAEYLVLLTDVPGVLMDGKVVPEIKSSEAEEVAKKVGPGMNIKIIMAGRVASGGTKV
VICDGTVPDPLKCLEERSGTWVVP

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=209, Percent_Identity=33.4928229665072, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_IGNH4 (A8AA51)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435210.1
- ProteinModelPortal:   A8AA51
- SMR:   A8AA51
- STRING:   A8AA51
- GeneID:   5563045
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0621
- eggNOG:   arNOG04941
- HOGENOM:   HBG497643
- OMA:   YLPVLTP
- BioCyc:   IHOS453591:IGNI_0621-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_A
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 28079; Mature: 28079

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: BINDING 61-61 BINDING 169-169

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVKAGGRTLLNNMDEIVKSISRLEKAVFVHGGGDLVDEWERKMGMEPQFKVSASGIKF
CEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCEEEECCCEEE
RYTDEKELEVFVAVLGGLLNKKIVASFASYGRGAVGLTGADGPSVIAERKKKVIVQEKVG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
ERLVKRAIAGGYTGKIKEVKTDLIKALVERGLVPVVAPIALSPEGELLNVNGDQMAAELA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCHHHHHHHHH
KALSAEYLVLLTDVPGVLMDGKVVPEIKSSEAEEVAKKVGPGMNIKIIMAGRVASGGTKV
HHHCCCEEEEEECCCCEEECCEECCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCEE
VICDGTVPDPLKCLEERSGTWVVP
EEECCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIVVKAGGRTLLNNMDEIVKSISRLEKAVFVHGGGDLVDEWERKMGMEPQFKVSASGIKF
CEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCEEEECCCEEE
RYTDEKELEVFVAVLGGLLNKKIVASFASYGRGAVGLTGADGPSVIAERKKKVIVQEKVG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
ERLVKRAIAGGYTGKIKEVKTDLIKALVERGLVPVVAPIALSPEGELLNVNGDQMAAELA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCHHHHHHHHH
KALSAEYLVLLTDVPGVLMDGKVVPEIKSSEAEEVAKKVGPGMNIKIIMAGRVASGGTKV
HHHCCCEEEEEECCCCEEECCEECCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCEE
VICDGTVPDPLKCLEERSGTWVVP
EEECCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA