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The map label for this gene is ahpF [C]

Identifier: 156937410

GI number: 156937410

Start: 552058

End: 552975

Strand: Reverse

Name: ahpF [C]

Synonym: Igni_0617

Alternate gene names: 156937410

Gene position: 552975-552058 (Counterclockwise)

Preceding gene: 156937411

Following gene: 156937409

Centisome position: 42.62

GC content: 57.3

Gene sequence:

>918_bases
ATGAGGGACGCGCTGGTGGTGGGCGCCGGACCAGCCGGCCTGACGGCGGCCGCCACCCTCAAGCAGTACGGCGTAGAGCC
TTTGGTGATAGAGGCGGAGAGGGTAATGGCCACGGTTTACTCATACGCTTGGAAGCCCGTGGAAAACTACCCCGGGTTCG
ACGGGAAAAGGGCAATAGAAATTGCTAGAGCCTTCGAAGAGATGCAGAAGTTCTTCGGGGTGGAGGTAGTTGAGAAGGAG
AGGGTCGTTAAGGCGTGGAAGGAGGGGGATAAGATAGTGCTGGGCACCCAGAGCGGGAACGAGTACGAAGGGAAGGTCCT
CATAATAGCTATAGGCATACTGGGCAAGCCCAGGAGGCTAGGCATTCCCAACGAGGACGCGCCCAACGTTCACTATATAG
TTAAGGATCCTACAGCTTTCGCGGGTTCTAAGGTAGTTGTCGTCGGCGGGGGAGACACAGCCGTCGACACGGCGACCGTG
TTAGCCGAGAGCGGGGCCCAAGTAACCATAGTTCACCGCAGGGACCAGTTCAGGGCCCCCATGAGGAGCATCGAAAGGAT
GGTGAGGGCCGGAGTTAAGATGGTATTGAACAGCGTTCCCAAGGAGATAATAGCAAAGGATGGCAAGGCCACGGCTTTGG
TGGTGACCCACAAGGAGGGGGGCGAGACGGTGCTCCCTCTGGACCACTTGGTCATATCCATAGGCTTCGAGCCCCCGGAC
TTGGAGTGGGTCAAGTCTCTCGGAGTTAACATGAGGGGTAAAGAAATACTAGTGGACGATAAGATGAGGACGAACGTTAA
GGGGGTGTTCGCGGCAGGGGACATAACTCCGGCCCCCAAGAGGATACTGGTGGCGGCGGCCCAAGGTTACATTGCCGGGT
TCACGGCTTTTAGGTACATACGCACTGGCGTGTGGTAA

Upstream 100 bases:

>100_bases
ACTCCATGAAACCGTCCCCGTGTTCTAGCTTCTACGGCGTAGTTAGTGAATATATTGGCCTTAAAGATCTCGCAGAGAGG
CTGTGTGGGGTGAAGGTGGG

Downstream 100 bases:

>100_bases
TTATTCCCCCTCCTCCGTCTGTGGGTGGTCGTAAGCTTTGAGTGGCCCGGGGGCAACGGCAGTCGGAATTAAGGTAAAGG
ACGGCGTCGTGTTGGCGGCC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: FNR; Fd-NADP+ reductase

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIEIARAFEEMQKFFGVEVVEKE
RVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRLGIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATV
LAESGAQVTIVHRRDQFRAPMRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPD
LEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYIRTGVW

Sequences:

>Translated_305_residues
MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIEIARAFEEMQKFFGVEVVEKE
RVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRLGIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATV
LAESGAQVTIVHRRDQFRAPMRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPD
LEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYIRTGVW
>Mature_305_residues
MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIEIARAFEEMQKFFGVEVVEKE
RVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRLGIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATV
LAESGAQVTIVHRRDQFRAPMRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPD
LEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYIRTGVW

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Homo sapiens, GI21389617, Length=297, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI65787454, Length=297, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI226437568, Length=297, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081763, Length=268, Percent_Identity=29.1044776119403, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=27.2435897435897, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789606, Length=327, Percent_Identity=23.5474006116208, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082180, Length=327, Percent_Identity=24.4648318042813, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320560, Length=319, Percent_Identity=28.2131661442006, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=27.3015873015873, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FENR_IGNH4 (A8AA47)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435206.1
- ProteinModelPortal:   A8AA47
- STRING:   A8AA47
- GeneID:   5562794
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0617
- eggNOG:   arNOG07126
- HOGENOM:   HBG669726
- BioCyc:   IHOS453591:IGNI_0617-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 33025; Mature: 33025

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: BINDING 31-31 BINDING 42-42 BINDING 82-82 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIE
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IARAFEEMQKFFGVEVVEKERVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRL
HHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCC
GIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATVLAESGAQVTIVHRRDQFRAP
CCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHH
MRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPD
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCEEEEHHHEEEEECCCCCC
LEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYI
HHHHHHCCCCCCCCEEEECCCHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHH
RTGVW
HHCCC
>Mature Secondary Structure
MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIE
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IARAFEEMQKFFGVEVVEKERVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRL
HHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCC
GIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATVLAESGAQVTIVHRRDQFRAP
CCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHH
MRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPD
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCEEEEHHHEEEEECCCCCC
LEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYI
HHHHHHCCCCCCCCEEEECCCHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHH
RTGVW
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA