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The map label for this gene is psmB1

Identifier: 156937409

GI number: 156937409

Start: 551424

End: 552020

Strand: Reverse

Name: psmB1

Synonym: Igni_0616

Alternate gene names: 156937409

Gene position: 552020-551424 (Counterclockwise)

Preceding gene: 156937410

Following gene: 156937408

Centisome position: 42.54

GC content: 56.28

Gene sequence:

>597_bases
TTGAGTGGCCCGGGGGCAACGGCAGTCGGAATTAAGGTAAAGGACGGCGTCGTGTTGGCGGCCGAGAGGAGGATGAGCTA
CGGAGGCTTCATAATGAGCAAAGCCGCTAGGAAGGTGTTTAAGGTAGGAGACAGGATGGGGATGGCGTGCGCCGGCCTTT
ACGCGGACATGCAAGCGATAGCTAGGGCTCTGGAGAACGAGATAAGGTACTACGAGATATCCAATAAGAGAAAAATGAAA
GTGAGGTCCGCGGCGAGGCTGTTGGGACTCATCCTCTACTCGAACAAGCTGTTCCCGCTAATGACGGAAACGGTCTTCGG
GGGCTACGACGACGAACCGAGGATATTCGTGTTGGACCCCGTCGGCTCCGTCATAGAGGAGAAGTACTCGGCCGTGGGGA
CCGGAGCGCCGCTAGCGATGGCCTTGTTGGACAAGGAGTATAGGGAGGACATGAGTTTGGAAGAGGCTCAAAACCTAGCC
ATAGAGAGCGTGAAGGTAGCGAGCGGACGCGACAGCTTGTCCGGCGACGGTATAGACGTATTGGTCATTCCGTTCGGGGG
CAAGCCCAGCATAAGGACAGTAAGCTTAGAGGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCCAAGGTTACATTGCCGGGTTCACGGCTTTTAGGTACATACGCACTGGCGTGTGGTAATTATTCCCCCTCCTCCG
TCTGTGGGTGGTCGTAAGCT

Downstream 100 bases:

>100_bases
GCAAGATATTAGTCGTCCTAGCGTTCTCCGCCTCTGAGGAAAAGATGTTCAGCGTGGCTACAGTTACGGAGACGAAAGCG
ATACTTTTGGGCTCTCAAGT

Product: proteasome endopeptidase complex

Products: NA

Alternate protein names: 20S proteasome beta subunit 1; Proteasome core protein PsmB 1

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSGPGATAVGIKVKDGVVLAAERRMSYGGFIMSKAARKVFKVGDRMGMACAGLYADMQAIARALENEIRYYEISNKRKMK
VRSAARLLGLILYSNKLFPLMTETVFGGYDDEPRIFVLDPVGSVIEEKYSAVGTGAPLAMALLDKEYREDMSLEEAQNLA
IESVKVASGRDSLSGDGIDVLVIPFGGKPSIRTVSLEA

Sequences:

>Translated_198_residues
MSGPGATAVGIKVKDGVVLAAERRMSYGGFIMSKAARKVFKVGDRMGMACAGLYADMQAIARALENEIRYYEISNKRKMK
VRSAARLLGLILYSNKLFPLMTETVFGGYDDEPRIFVLDPVGSVIEEKYSAVGTGAPLAMALLDKEYREDMSLEEAQNLA
IESVKVASGRDSLSGDGIDVLVIPFGGKPSIRTVSLEA
>Mature_197_residues
SGPGATAVGIKVKDGVVLAAERRMSYGGFIMSKAARKVFKVGDRMGMACAGLYADMQAIARALENEIRYYEISNKRKMKV
RSAARLLGLILYSNKLFPLMTETVFGGYDDEPRIFVLDPVGSVIEEKYSAVGTGAPLAMALLDKEYREDMSLEEAQNLAI
ESVKVASGRDSLSGDGIDVLVIPFGGKPSIRTVSLEA

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family

Homologues:

Organism=Homo sapiens, GI4506201, Length=180, Percent_Identity=30, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI4506193, Length=205, Percent_Identity=28.2926829268293, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI153791216, Length=180, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4506191, Length=192, Percent_Identity=27.6041666666667, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI4506203, Length=180, Percent_Identity=30, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI4758970, Length=172, Percent_Identity=28.4883720930233, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI73747875, Length=172, Percent_Identity=28.4883720930233, Blast_Score=81, Evalue=5e-16,
Organism=Homo sapiens, GI22538465, Length=202, Percent_Identity=27.7227722772277, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI23110925, Length=181, Percent_Identity=25.9668508287293, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI195539356, Length=134, Percent_Identity=30.5970149253731, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508499, Length=163, Percent_Identity=33.1288343558282, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541700, Length=181, Percent_Identity=27.6243093922652, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554384, Length=200, Percent_Identity=26.5, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508495, Length=184, Percent_Identity=25, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508493, Length=196, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17535357, Length=186, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319430, Length=199, Percent_Identity=30.1507537688442, Blast_Score=95, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325360, Length=181, Percent_Identity=27.0718232044199, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324731, Length=188, Percent_Identity=28.1914893617021, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322459, Length=185, Percent_Identity=29.1891891891892, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321574, Length=188, Percent_Identity=27.1276595744681, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320849, Length=193, Percent_Identity=25.3886010362694, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323547, Length=186, Percent_Identity=26.3440860215054, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI20130281, Length=172, Percent_Identity=33.7209302325581, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737605, Length=205, Percent_Identity=28.2926829268293, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24584895, Length=172, Percent_Identity=34.3023255813954, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355573, Length=191, Percent_Identity=31.413612565445, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652553, Length=191, Percent_Identity=31.413612565445, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639979, Length=193, Percent_Identity=29.0155440414508, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24664391, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28573221, Length=181, Percent_Identity=26.5193370165746, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355629, Length=183, Percent_Identity=25.6830601092896, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19921232, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653999, Length=181, Percent_Identity=23.7569060773481, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSB1_IGNH4 (A8AA46)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435205.1
- ProteinModelPortal:   A8AA46
- SMR:   A8AA46
- MEROPS:   T01.002
- GeneID:   5561828
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0616
- eggNOG:   arNOG09775
- HOGENOM:   HBG499923
- OMA:   EKRVSYG
- GO:   GO:0005737
- HAMAP:   MF_02113_A
- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353
- PRINTS:   PR00141
- TIGRFAMs:   TIGR03634

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 21381; Mature: 21250

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00854 PROTEASOME_B_1; PS51476 PROTEASOME_B_2

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPGATAVGIKVKDGVVLAAERRMSYGGFIMSKAARKVFKVGDRMGMACAGLYADMQAI
CCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ARALENEIRYYEISNKRKMKVRSAARLLGLILYSNKLFPLMTETVFGGYDDEPRIFVLDP
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECC
VGSVIEEKYSAVGTGAPLAMALLDKEYREDMSLEEAQNLAIESVKVASGRDSLSGDGIDV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCCCEEE
LVIPFGGKPSIRTVSLEA
EEEECCCCCCEEEEEECC
>Mature Secondary Structure 
SGPGATAVGIKVKDGVVLAAERRMSYGGFIMSKAARKVFKVGDRMGMACAGLYADMQAI
CCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ARALENEIRYYEISNKRKMKVRSAARLLGLILYSNKLFPLMTETVFGGYDDEPRIFVLDP
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECC
VGSVIEEKYSAVGTGAPLAMALLDKEYREDMSLEEAQNLAIESVKVASGRDSLSGDGIDV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCCCEEE
LVIPFGGKPSIRTVSLEA
EEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA