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The map label for this gene is aroC

Identifier: 156937324

GI number: 156937324

Start: 473818

End: 474960

Strand: Direct

Name: aroC

Synonym: Igni_0531

Alternate gene names: 156937324

Gene position: 473818-474960 (Clockwise)

Preceding gene: 156937320

Following gene: 156937327

Centisome position: 36.52

GC content: 63.25

Gene sequence:

>1143_bases
TTGGGCGGAAACACAATAGGTAAGATGTTCAGCGTAACTACTTGGGGGGAGAGCCACGGCAAGGCGATAGGCGCGGTGAT
AGACGGCTGCCCGGCCGGCTTGCCCCTCAGCGAGGAGGACCTCTTGGTCGAGCTCTCGCTCCGCAGGCCGGGGAGGAGGT
TCACCACCCCGAGGAGGGAGCCGGACGTCCCAGAGATACTGAGCGGGGTGTTCAACGGAAAGACCACCGGCATGCCTATT
TCAATAATAATAAGAAATAGGGACGTTATCTCGAGCTACTACGAGAAGATCAAGGAAACTCCCAGGCCAGGTCACGCGGA
CTTAGCGTACATAAAGAAGTACGGCTACGAGCACTGGGACTACAGGGGAGGCGGGAGGGCCTCTGGGAGGGAGACCGCTG
CTAGAGTGGCGGCGGGGGCGGTGGCCAAGAAGCTGCTCGGCTGCTTAGGAGTGGTGGTCTCCGGCTACGTGGTGGAGCTG
GGCGGGGTAGAGTTCCCGTCAGCCGAGGACGCGGAGGAGTCCTTGAGGTCCCGCCTCTCGCCCTTCCGGGTCTTGTGTTG
TGAGGAGAAGGCCGAGGAGGTCTTGAAAGAGGCGCTCGAGAGGAGGGACAGCGTGGGCGGGGTGGTGGAAGCGGTCGCGT
GGAACGCGCCGGCGGGCTTGGGCGAGCCGGTGTTCGACAAGCTCAAGGCGGACCTCGCGAAGGCCATGATGAGCATACCC
GCCAGCGTGGGCTTCGAGGTAGGTTGGGGCTTCAAGCTGGCCCGGCTCAGGGGGAGCGAGGCGAGGGACAAGATAGTGAG
CTCGGCCGGCGAGGCGACTGTGGAGGGGGACAAGGCCGGCGGAATGCTGGGCGGAATAAGCGTCGGGGCGCCGATAAGGA
TTAGGGTCGCGTTCAAGCCCACGAGCTCCATAATGATCCCGGAAAAGACGGTGAACATACACACGCTGGAGGAGACTGAG
GTGGAGGTGCCCGGGAGGCACGACCCGGCCATAGTTCTGAGGGCCGTTTCGGTGGTCGAGTCGATGTTCGCCATAGTCTT
GGTGGATCACGCGATCAGGGCCGGCCTCTTGAACCCGGTGAGGGTCGAGTGGGGCCCCCACTGCCAGAGGGTCTGGGAGC
TCTACGCGGATAGGGTGCCCTAG

Upstream 100 bases:

>100_bases
CAACCTTTGGGGCGCCATTCTCCCTTTTTATTGAAACTTGGCCGGACCGGCCGCAAAGCGGTTTTCCCCTCGTCCCCTCC
TCAAAAGGGGACCACATGCT

Downstream 100 bases:

>100_bases
CGCTGCCAACACACGCCCTTTACCCTCATAACGAATGGCTTGTTCAGCTCACCCGATATTTCCACCTCGAGCTCCGGGAG
GAACTTCTTAACCACGTGCA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MGGNTIGKMFSVTTWGESHGKAIGAVIDGCPAGLPLSEEDLLVELSLRRPGRRFTTPRREPDVPEILSGVFNGKTTGMPI
SIIIRNRDVISSYYEKIKETPRPGHADLAYIKKYGYEHWDYRGGGRASGRETAARVAAGAVAKKLLGCLGVVVSGYVVEL
GGVEFPSAEDAEESLRSRLSPFRVLCCEEKAEEVLKEALERRDSVGGVVEAVAWNAPAGLGEPVFDKLKADLAKAMMSIP
ASVGFEVGWGFKLARLRGSEARDKIVSSAGEATVEGDKAGGMLGGISVGAPIRIRVAFKPTSSIMIPEKTVNIHTLEETE
VEVPGRHDPAIVLRAVSVVESMFAIVLVDHAIRAGLLNPVRVEWGPHCQRVWELYADRVP

Sequences:

>Translated_380_residues
MGGNTIGKMFSVTTWGESHGKAIGAVIDGCPAGLPLSEEDLLVELSLRRPGRRFTTPRREPDVPEILSGVFNGKTTGMPI
SIIIRNRDVISSYYEKIKETPRPGHADLAYIKKYGYEHWDYRGGGRASGRETAARVAAGAVAKKLLGCLGVVVSGYVVEL
GGVEFPSAEDAEESLRSRLSPFRVLCCEEKAEEVLKEALERRDSVGGVVEAVAWNAPAGLGEPVFDKLKADLAKAMMSIP
ASVGFEVGWGFKLARLRGSEARDKIVSSAGEATVEGDKAGGMLGGISVGAPIRIRVAFKPTSSIMIPEKTVNIHTLEETE
VEVPGRHDPAIVLRAVSVVESMFAIVLVDHAIRAGLLNPVRVEWGPHCQRVWELYADRVP
>Mature_379_residues
GGNTIGKMFSVTTWGESHGKAIGAVIDGCPAGLPLSEEDLLVELSLRRPGRRFTTPRREPDVPEILSGVFNGKTTGMPIS
IIIRNRDVISSYYEKIKETPRPGHADLAYIKKYGYEHWDYRGGGRASGRETAARVAAGAVAKKLLGCLGVVVSGYVVELG
GVEFPSAEDAEESLRSRLSPFRVLCCEEKAEEVLKEALERRDSVGGVVEAVAWNAPAGLGEPVFDKLKADLAKAMMSIPA
SVGFEVGWGFKLARLRGSEARDKIVSSAGEATVEGDKAGGMLGGISVGAPIRIRVAFKPTSSIMIPEKTVNIHTLEETEV
EVPGRHDPAIVLRAVSVVESMFAIVLVDHAIRAGLLNPVRVEWGPHCQRVWELYADRVP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=48.9010989010989, Blast_Score=291, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6321290, Length=364, Percent_Identity=40.3846153846154, Blast_Score=246, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_IGNH4 (A8A9W1)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435120.1
- ProteinModelPortal:   A8A9W1
- SMR:   A8A9W1
- STRING:   A8A9W1
- GeneID:   5562364
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0531
- eggNOG:   arNOG04618
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   IHOS453591:IGNI_0531-MONOMER
- HAMAP:   MF_00300_A
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 40953; Mature: 40821

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGNTIGKMFSVTTWGESHGKAIGAVIDGCPAGLPLSEEDLLVELSLRRPGRRFTTPRRE
CCCCHHHHHEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
PDVPEILSGVFNGKTTGMPISIIIRNRDVISSYYEKIKETPRPGHADLAYIKKYGYEHWD
CCHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
YRGGGRASGRETAARVAAGAVAKKLLGCLGVVVSGYVVELGGVEFPSAEDAEESLRSRLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCC
PFRVLCCEEKAEEVLKEALERRDSVGGVVEAVAWNAPAGLGEPVFDKLKADLAKAMMSIP
HHEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
ASVGFEVGWGFKLARLRGSEARDKIVSSAGEATVEGDKAGGMLGGISVGAPIRIRVAFKP
HHCCCCCCCCEEEEHHCCCHHHHHHHHCCCCCEECCCCCCCEEECCCCCCCEEEEEEECC
TSSIMIPEKTVNIHTLEETEVEVPGRHDPAIVLRAVSVVESMFAIVLVDHAIRAGLLNPV
CCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
RVEWGPHCQRVWELYADRVP
EECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GGNTIGKMFSVTTWGESHGKAIGAVIDGCPAGLPLSEEDLLVELSLRRPGRRFTTPRRE
CCCHHHHHEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
PDVPEILSGVFNGKTTGMPISIIIRNRDVISSYYEKIKETPRPGHADLAYIKKYGYEHWD
CCHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
YRGGGRASGRETAARVAAGAVAKKLLGCLGVVVSGYVVELGGVEFPSAEDAEESLRSRLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCC
PFRVLCCEEKAEEVLKEALERRDSVGGVVEAVAWNAPAGLGEPVFDKLKADLAKAMMSIP
HHEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
ASVGFEVGWGFKLARLRGSEARDKIVSSAGEATVEGDKAGGMLGGISVGAPIRIRVAFKP
HHCCCCCCCCEEEEHHCCCHHHHHHHHCCCCCEECCCCCCCEEECCCCCCCEEEEEEECC
TSSIMIPEKTVNIHTLEETEVEVPGRHDPAIVLRAVSVVESMFAIVLVDHAIRAGLLNPV
CCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
RVEWGPHCQRVWELYADRVP
EECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA