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The map label for this gene is trpG [H]

Identifier: 156937260

GI number: 156937260

Start: 414641

End: 415246

Strand: Direct

Name: trpG [H]

Synonym: Igni_0466

Alternate gene names: 156937260

Gene position: 414641-415246 (Clockwise)

Preceding gene: 156937258

Following gene: 156937261

Centisome position: 31.96

GC content: 60.23

Gene sequence:

>606_bases
TTGAGGCCAGTCCTCTTGGTAGACCACAGGGACAGCTTCGTGCACAACGTAGAACAGATAATAATGGAAGAGGGTTTCGC
CGTGGCCACCTTGCGCCAGGAGGAGCTCTCGCCCTCGGCGGCTGAGAGGTTGAGGCCCTCCGCGATAGTCCTCTCCCCCG
GTCCCGGCAACCCCTACGCGCAGAAGGACAAGTTCGAGACCAGCATAAGGATCGTGAACAAGTTCAAAGGCAAAGTGCCT
ATCCTCGGCATATGCTTGGGGATGCAAATAATAAACGTGGCCTTGGGCGGTACCTTGAGGAAGGCAAAGAGGGTCTACCA
CGGGGTGGTGGACGAAATAGTAGTGAAGGACAGAGGTCCCCTGTTCTTCGGCCTCCCGGAGAGGTTCCCCGCCACGCGCT
ACCACAGCTTGGTGGTGGACGAGCTGGGGGAGGGGCTGGTGGTGGAGGCCCTCTCGCTGAGCGACGGGGAGGTGATGGCG
GTGAGGCACGAGGAGCTGCCGCTCTTCGGCCTCCAGTTCCACCCGGAGAGCATAGGCACCTTGCCCGCCGGCCAGAAGAT
AATTAGGAACTTCTTGGCCCTCTCCAAGCCCCTCTCGCTGTTCTGA

Upstream 100 bases:

>100_bases
TTTAGTTCGAGCTCACAATTGTATAATACTTCTGTTGAACCGCCAAGAACGGTCGCGCCAGAGTTAAGGGCCCCCGAAGC
CGTCCGGGAGGAAACGCGCG

Downstream 100 bases:

>100_bases
GGTGGTGCGCCACGAGGCCCTCCGACGTGAGGACCTTCGCCTTCTGCCCTAGGTTGTACTTCTTCGAGAGGCACTTAGGT
AAAGAGACTACGTTATACCA

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRPVLLVDHRDSFVHNVEQIIMEEGFAVATLRQEELSPSAAERLRPSAIVLSPGPGNPYAQKDKFETSIRIVNKFKGKVP
ILGICLGMQIINVALGGTLRKAKRVYHGVVDEIVVKDRGPLFFGLPERFPATRYHSLVVDELGEGLVVEALSLSDGEVMA
VRHEELPLFGLQFHPESIGTLPAGQKIIRNFLALSKPLSLF

Sequences:

>Translated_201_residues
MRPVLLVDHRDSFVHNVEQIIMEEGFAVATLRQEELSPSAAERLRPSAIVLSPGPGNPYAQKDKFETSIRIVNKFKGKVP
ILGICLGMQIINVALGGTLRKAKRVYHGVVDEIVVKDRGPLFFGLPERFPATRYHSLVVDELGEGLVVEALSLSDGEVMA
VRHEELPLFGLQFHPESIGTLPAGQKIIRNFLALSKPLSLF
>Mature_201_residues
MRPVLLVDHRDSFVHNVEQIIMEEGFAVATLRQEELSPSAAERLRPSAIVLSPGPGNPYAQKDKFETSIRIVNKFKGKVP
ILGICLGMQIINVALGGTLRKAKRVYHGVVDEIVVKDRGPLFFGLPERFPATRYHSLVVDELGEGLVVEALSLSDGEVMA
VRHEELPLFGLQFHPESIGTLPAGQKIIRNFLALSKPLSLF

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=147, Percent_Identity=37.4149659863946, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789760, Length=191, Percent_Identity=39.2670157068063, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787517, Length=199, Percent_Identity=36.6834170854271, Blast_Score=108, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322638, Length=196, Percent_Identity=36.734693877551, Blast_Score=118, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=32.7102803738318, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281365319, Length=146, Percent_Identity=34.9315068493151, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22187; Mature: 22187

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVLLVDHRDSFVHNVEQIIMEEGFAVATLRQEELSPSAAERLRPSAIVLSPGPGNPYA
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHHCCHHHHHHCCCCEEEEECCCCCCCC
QKDKFETSIRIVNKFKGKVPILGICLGMQIINVALGGTLRKAKRVYHGVVDEIVVKDRGP
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
LFFGLPERFPATRYHSLVVDELGEGLVVEALSLSDGEVMAVRHEELPLFGLQFHPESIGT
EEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCC
LPAGQKIIRNFLALSKPLSLF
CCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPVLLVDHRDSFVHNVEQIIMEEGFAVATLRQEELSPSAAERLRPSAIVLSPGPGNPYA
CCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHHCCHHHHHHCCCCEEEEECCCCCCCC
QKDKFETSIRIVNKFKGKVPILGICLGMQIINVALGGTLRKAKRVYHGVVDEIVVKDRGP
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
LFFGLPERFPATRYHSLVVDELGEGLVVEALSLSDGEVMAVRHEELPLFGLQFHPESIGT
EEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCC
LPAGQKIIRNFLALSKPLSLF
CCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8416906; 11427726; 10449718 [H]