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The map label for this gene is 156937246

Identifier: 156937246

GI number: 156937246

Start: 399220

End: 399969

Strand: Direct

Name: 156937246

Synonym: Igni_0452

Alternate gene names: NA

Gene position: 399220-399969 (Clockwise)

Preceding gene: 156937245

Following gene: 156937250

Centisome position: 30.77

GC content: 58.53

Gene sequence:

>750_bases
TTGAGCTTCGTGCCCCCCGACCACCCCAGGTTCCTTTCCCTAATGTATAGGGAGAGGCTGGTCGAGAAGTTCAAGGAAGG
GGTAGTGGTCGCGCAAGGCTTGATAGCGCACGGGAGGGGAGAGGCCTTCGATTACATACTGGGCGAGCAGACCATCCCCC
CGGCCTTGGAGGCCGAAAAGGCAGCAGCGGCGCTGCTCAAGCTGGCGCGCAAGCCGGTCATAAGCGTCAACGGGAACGCG
GCCGCCTTGGTCCCCGGGGAGTTGGTGGAGCTCAGCAAGGCCCTAAACGCCCCCCTCGAGGTCAACTTGTTCTATAGGTC
CGAGGAGAGGGCCAAGAGGATAGCTGAGCTCCTCAAGGCCCACGGGGCGGAGGAGGTCTTGTGGAGGCCCGACCAAGAGC
TGCCGGGGCTTAGCTCCGAGAGGAGGAGGGTGAGCTCCAAGGGCATAGCCTCTGCTGACGTGGTGTTGGTGAGCTTGGAG
GACGGGGACCGCACGGAAGCGTTGAAGAGGAACGGGAAGAAGGTAATTGCAATAGACTTGAACCCTTTCTCGAGGACCTC
CCTAACTGCCGACATAACTATAGTTGACAACGTGATTAGGGCAATACCGAACATAACGAAGTTCGTAAAGGCTATGAGCG
AGAGGGAGGCGGAGGAGGCTTTGGAGAGGTTCGACAACGCGAGGAACTTGAGGGAGGTGGTCAAATGGATAAAGAAGTGG
CTGGATGCTAAGACTTCAGAGCTCCTCTAG

Upstream 100 bases:

>100_bases
AGGAGGAGAAGAAGGAGGCCGTCAGCGAGGAGGAGCTCTCCGCCGGCCTGGGAGCCCTCTTCGGCTAAAACCCCGCTTTT
TGTGTACGCTGGGTGTCGCC

Downstream 100 bases:

>100_bases
GTGTTTTGCTACCTCCTCCACGGTGAGCTTCCTCGCGGTCTTGGTGTCCACCGGGACCACTGCAACTTCGTAAAGCTCCG
GGTCCTTCTCGCTCTCCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSFVPPDHPRFLSLMYRERLVEKFKEGVVVAQGLIAHGRGEAFDYILGEQTIPPALEAEKAAAALLKLARKPVISVNGNA
AALVPGELVELSKALNAPLEVNLFYRSEERAKRIAELLKAHGAEEVLWRPDQELPGLSSERRRVSSKGIASADVVLVSLE
DGDRTEALKRNGKKVIAIDLNPFSRTSLTADITIVDNVIRAIPNITKFVKAMSEREAEEALERFDNARNLREVVKWIKKW
LDAKTSELL

Sequences:

>Translated_249_residues
MSFVPPDHPRFLSLMYRERLVEKFKEGVVVAQGLIAHGRGEAFDYILGEQTIPPALEAEKAAAALLKLARKPVISVNGNA
AALVPGELVELSKALNAPLEVNLFYRSEERAKRIAELLKAHGAEEVLWRPDQELPGLSSERRRVSSKGIASADVVLVSLE
DGDRTEALKRNGKKVIAIDLNPFSRTSLTADITIVDNVIRAIPNITKFVKAMSEREAEEALERFDNARNLREVVKWIKKW
LDAKTSELL
>Mature_248_residues
SFVPPDHPRFLSLMYRERLVEKFKEGVVVAQGLIAHGRGEAFDYILGEQTIPPALEAEKAAAALLKLARKPVISVNGNAA
ALVPGELVELSKALNAPLEVNLFYRSEERAKRIAELLKAHGAEEVLWRPDQELPGLSSERRRVSSKGIASADVVLVSLED
GDRTEALKRNGKKVIAIDLNPFSRTSLTADITIVDNVIRAIPNITKFVKAMSEREAEEALERFDNARNLREVVKWIKKWL
DAKTSELL

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction [H]

COG id: COG1701

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal pantothenate synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002855
- ProDom:   PD016827 [H]

Pfam domain/function: PF02006 DUF137 [H]

EC number: NA

Molecular weight: Translated: 27685; Mature: 27554

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVPPDHPRFLSLMYRERLVEKFKEGVVVAQGLIAHGRGEAFDYILGEQTIPPALEAEK
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHH
AAAALLKLARKPVISVNGNAAALVPGELVELSKALNAPLEVNLFYRSEERAKRIAELLKA
HHHHHHHHHHCCEEEECCCEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHH
HGAEEVLWRPDQELPGLSSERRRVSSKGIASADVVLVSLEDGDRTEALKRNGKKVIAIDL
CCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCEEEEEEC
NPFSRTSLTADITIVDNVIRAIPNITKFVKAMSEREAEEALERFDNARNLREVVKWIKKW
CCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LDAKTSELL
HCCHHHCCC
>Mature Secondary Structure 
SFVPPDHPRFLSLMYRERLVEKFKEGVVVAQGLIAHGRGEAFDYILGEQTIPPALEAEK
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHH
AAAALLKLARKPVISVNGNAAALVPGELVELSKALNAPLEVNLFYRSEERAKRIAELLKA
HHHHHHHHHHCCEEEECCCEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHH
HGAEEVLWRPDQELPGLSSERRRVSSKGIASADVVLVSLEDGDRTEALKRNGKKVIAIDL
CCCHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCEEEEEEC
NPFSRTSLTADITIVDNVIRAIPNITKFVKAMSEREAEEALERFDNARNLREVVKWIKKW
CCCCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LDAKTSELL
HCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]