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The map label for this gene is cutA [H]

Identifier: 156937195

GI number: 156937195

Start: 354883

End: 355191

Strand: Direct

Name: cutA [H]

Synonym: Igni_0401

Alternate gene names: 156937195

Gene position: 354883-355191 (Clockwise)

Preceding gene: 156937192

Following gene: 156937196

Centisome position: 27.35

GC content: 53.72

Gene sequence:

>309_bases
TTGATAGTCATCTTGACCACTTTCGGGAACGAAGAAGACGCCAAGAAAGTGGCAAGGACCTTGGTAGAGGAGGGGCTCGT
CGCTTGCGCTTGGGTTACCCAAAAGGTGAGGAGCTTCTACGTGTGGAAGGGCAAGCTGGAGGAGGACGAGGAGGTGGTAG
TAGTATTGAAGGCTCCTAAGAAGACGTTTGAGAAGGCAGTAAAGAGGCTGAGGGAGCTTCACCCCTACGAGGTGCCGGAG
ATAATTGCCTTCGAGGCTAATTACGTCCTCCCGGAGTACTTGAAGTGGGCTGAGGAGGTTTGCGGCTGA

Upstream 100 bases:

>100_bases
CGTACCTCCACTGGAACGGGCAGACGTGCAAGGCGACCGCCGGGGAGGGGGCGGCGATGGAGTAATGAAGGCGAAGGGCG
AGGGTCTAGGGGAAGGGGCG

Downstream 100 bases:

>100_bases
GGTTCGACGCCCGCAAGGGGGCCGAGCTGGCTAAGGTCAAACTATCGGAGGAGGAGCTCCAGAGGCTCCAGAAGGACTTA
GACGAGATGGCCGAGATGCT

Product: CutA1 divalent ion tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MIVILTTFGNEEDAKKVARTLVEEGLVACAWVTQKVRSFYVWKGKLEEDEEVVVVLKAPKKTFEKAVKRLRELHPYEVPE
IIAFEANYVLPEYLKWAEEVCG

Sequences:

>Translated_102_residues
MIVILTTFGNEEDAKKVARTLVEEGLVACAWVTQKVRSFYVWKGKLEEDEEVVVVLKAPKKTFEKAVKRLRELHPYEVPE
IIAFEANYVLPEYLKWAEEVCG
>Mature_102_residues
MIVILTTFGNEEDAKKVARTLVEEGLVACAWVTQKVRSFYVWKGKLEEDEEVVVVLKAPKKTFEKAVKRLRELHPYEVPE
IIAFEANYVLPEYLKWAEEVCG

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526026, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI62198241, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI62526024, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI62526022, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI7706244, Length=97, Percent_Identity=39.1752577319588, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790579, Length=95, Percent_Identity=32.6315789473684, Blast_Score=65, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565476, Length=96, Percent_Identity=41.6666666666667, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641937, Length=94, Percent_Identity=36.1702127659575, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 11787; Mature: 11787

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVILTTFGNEEDAKKVARTLVEEGLVACAWVTQKVRSFYVWKGKLEEDEEVVVVLKAPK
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCH
KTFEKAVKRLRELHPYEVPEIIAFEANYVLPEYLKWAEEVCG
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIVILTTFGNEEDAKKVARTLVEEGLVACAWVTQKVRSFYVWKGKLEEDEEVVVVLKAPK
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCH
KTFEKAVKRLRELHPYEVPEIIAFEANYVLPEYLKWAEEVCG
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]