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The map label for this gene is cdc6-1 [H]

Identifier: 156937045

GI number: 156937045

Start: 216447

End: 217658

Strand: Direct

Name: cdc6-1 [H]

Synonym: Igni_0250

Alternate gene names: 156937045

Gene position: 216447-217658 (Clockwise)

Preceding gene: 156937044

Following gene: 156937046

Centisome position: 16.68

GC content: 55.94

Gene sequence:

>1212_bases
GTGCTGACCGCGGACCTCGACGACATACTCGACGACGTCTTCGAACGGGTGACCAGCTCGAGGATATTCAAGAACAGGGA
CGTGCTGCTGCCGGATTACTTGCCTAACAAGCTTCCCCATAGAGAAGAACAAATAAGGAAGGTGGCCAGCGTCCTAGCCC
AAGCCCTCAAGGGCTACAAGCCGAACAACTTGTTCATATATGGCCTCACGGGCACCGGTAAGACAGCGGTCGTAAAGCTG
GTAGTCAAGAAGTTAAGTGAGAAAGCCGTCGAGAAGGGAGTTAAATTGAAAATAACCTTCATCAACACCAAGAGGGACGA
TACCCCGTATAGGGTGCTAGCGAGGATGCTGGAGGACATAGGGATAAGGGTACCCCCGACGGGAGTGGCGACGGCGGAGC
TCTACTCGAGGTTCAAGAAGTTCCTGGACAAGAAGGGAACTTTGATGATACTCGTGTTAGACGAGATAGACTATCACGTA
AAGAAGTACGGCGACGACTTGCTCTACAAGCTGACCAGGATAAACGAGGAGCTCCAAAGGTCCAAGGTATCCTTGGTTGG
AATAACGAACGACGTCAACTTCACCAGCTGGCTCGACCCTAGGGTAAAGTCCTCCTTGGGCGAGGAGGAGCTCGTGTTCC
CCCCGTACACGGCCGAGCAGCTGAGGGACATATTGAAGGACAGGGCGGAGATGGCGTTCGTAGAGGGGGTGCTGGGGGAG
GGAGTGATAGAGCTCTGCGCGGCCTTGGCTGCTAGGGAAAACGGGGACGCTAGGAAGGCCCTCGACTTGTTGAGGATATC
CGGCGAAATAGCCGAGAGGAGCGGCTCCTCGAAGGTTACCGTAGAGCACGTCAGGAGGGCTTGGGAGCAGATGGAGAAGG
ACAGGGTGGTGGAGATAGTGAAGAGCTTGCCCTTACACAGCAAGTTGATACTGTATTCCATACTCCTCTTGACGAAGGGC
GGGAAGACCACCTACACCGGCGAGGTGTACCGCAAGTACAAGGAGCTGACCGCGGAGCTCGGGATAGAGACCCTAACGCT
TAGGAGGGTCGGCGACTTGATTTCGGAGTTAGACATGTTGGGGCTCATCTCCACCGAGGTGGTGAGCAGGGGGAGGAGGG
GGCTCACTCGAGTGATCAGCTTGGAGAGCGACCCAGAGGCTATAAGAAAGGGGCTGCTCGTGGACCCCACGGTGGCCGAG
GTCGCCGGTTAG

Upstream 100 bases:

>100_bases
AAATCGAGAGGATAGCGCTCTCCTCGCGCTAACCTTCATTCCTTTTTCCTTTCTTCGGCTATTTATCCCGGGCCGGCGCC
TACACTGTGACGGGTGACCA

Downstream 100 bases:

>100_bases
CTTTGACGACGGTCGCCCCTCCGCGGCGTGTCCGGTCGTAGCCCTCCAGACCGCCCTCTGGCCCCCCGTGGTCGTAAGGC
TCCAAGCGCACGCGTTCAAG

Product: ORC complex protein Cdc6/Orc1

Products: NA

Alternate protein names: CDC6 homolog 1 [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLTADLDDILDDVFERVTSSRIFKNRDVLLPDYLPNKLPHREEQIRKVASVLAQALKGYKPNNLFIYGLTGTGKTAVVKL
VVKKLSEKAVEKGVKLKITFINTKRDDTPYRVLARMLEDIGIRVPPTGVATAELYSRFKKFLDKKGTLMILVLDEIDYHV
KKYGDDLLYKLTRINEELQRSKVSLVGITNDVNFTSWLDPRVKSSLGEEELVFPPYTAEQLRDILKDRAEMAFVEGVLGE
GVIELCAALAARENGDARKALDLLRISGEIAERSGSSKVTVEHVRRAWEQMEKDRVVEIVKSLPLHSKLILYSILLLTKG
GKTTYTGEVYRKYKELTAELGIETLTLRRVGDLISELDMLGLISTEVVSRGRRGLTRVISLESDPEAIRKGLLVDPTVAE
VAG

Sequences:

>Translated_403_residues
MLTADLDDILDDVFERVTSSRIFKNRDVLLPDYLPNKLPHREEQIRKVASVLAQALKGYKPNNLFIYGLTGTGKTAVVKL
VVKKLSEKAVEKGVKLKITFINTKRDDTPYRVLARMLEDIGIRVPPTGVATAELYSRFKKFLDKKGTLMILVLDEIDYHV
KKYGDDLLYKLTRINEELQRSKVSLVGITNDVNFTSWLDPRVKSSLGEEELVFPPYTAEQLRDILKDRAEMAFVEGVLGE
GVIELCAALAARENGDARKALDLLRISGEIAERSGSSKVTVEHVRRAWEQMEKDRVVEIVKSLPLHSKLILYSILLLTKG
GKTTYTGEVYRKYKELTAELGIETLTLRRVGDLISELDMLGLISTEVVSRGRRGLTRVISLESDPEAIRKGLLVDPTVAE
VAG
>Mature_403_residues
MLTADLDDILDDVFERVTSSRIFKNRDVLLPDYLPNKLPHREEQIRKVASVLAQALKGYKPNNLFIYGLTGTGKTAVVKL
VVKKLSEKAVEKGVKLKITFINTKRDDTPYRVLARMLEDIGIRVPPTGVATAELYSRFKKFLDKKGTLMILVLDEIDYHV
KKYGDDLLYKLTRINEELQRSKVSLVGITNDVNFTSWLDPRVKSSLGEEELVFPPYTAEQLRDILKDRAEMAFVEGVLGE
GVIELCAALAARENGDARKALDLLRISGEIAERSGSSKVTVEHVRRAWEQMEKDRVVEIVKSLPLHSKLILYSILLLTKG
GKTTYTGEVYRKYKELTAELGIETLTLRRVGDLISELDMLGLISTEVVSRGRRGLTRVISLESDPEAIRKGLLVDPTVAE
VAG

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=346, Percent_Identity=25.1445086705202, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI299890795, Length=344, Percent_Identity=24.4186046511628, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI299890793, Length=344, Percent_Identity=24.4186046511628, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI31795544, Length=344, Percent_Identity=24.4186046511628, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555708, Length=387, Percent_Identity=27.1317829457364, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17506005, Length=266, Percent_Identity=27.4436090225564, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17137456, Length=346, Percent_Identity=28.0346820809249, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355681, Length=340, Percent_Identity=24.7058823529412, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR002182
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09079 Cdc6_C; PF00931 NB-ARC [H]

EC number: NA

Molecular weight: Translated: 45242; Mature: 45242

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTADLDDILDDVFERVTSSRIFKNRDVLLPDYLPNKLPHREEQIRKVASVLAQALKGYK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PNNLFIYGLTGTGKTAVVKLVVKKLSEKAVEKGVKLKITFINTKRDDTPYRVLARMLEDI
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHC
GIRVPPTGVATAELYSRFKKFLDKKGTLMILVLDEIDYHVKKYGDDLLYKLTRINEELQR
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
SKVSLVGITNDVNFTSWLDPRVKSSLGEEELVFPPYTAEQLRDILKDRAEMAFVEGVLGE
HHEEEEEEECCCCCHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVIELCAALAARENGDARKALDLLRISGEIAERSGSSKVTVEHVRRAWEQMEKDRVVEIV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
KSLPLHSKLILYSILLLTKGGKTTYTGEVYRKYKELTAELGIETLTLRRVGDLISELDML
HHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GLISTEVVSRGRRGLTRVISLESDPEAIRKGLLVDPTVAEVAG
HHHHHHHHHCCHHHHHHHEECCCCHHHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MLTADLDDILDDVFERVTSSRIFKNRDVLLPDYLPNKLPHREEQIRKVASVLAQALKGYK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PNNLFIYGLTGTGKTAVVKLVVKKLSEKAVEKGVKLKITFINTKRDDTPYRVLARMLEDI
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHC
GIRVPPTGVATAELYSRFKKFLDKKGTLMILVLDEIDYHVKKYGDDLLYKLTRINEELQR
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
SKVSLVGITNDVNFTSWLDPRVKSSLGEEELVFPPYTAEQLRDILKDRAEMAFVEGVLGE
HHEEEEEEECCCCCHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVIELCAALAARENGDARKALDLLRISGEIAERSGSSKVTVEHVRRAWEQMEKDRVVEIV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
KSLPLHSKLILYSILLLTKGGKTTYTGEVYRKYKELTAELGIETLTLRRVGDLISELDML
HHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
GLISTEVVSRGRRGLTRVISLESDPEAIRKGLLVDPTVAEVAG
HHHHHHHHHCCHHHHHHHEECCCCHHHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]