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The map label for this gene is glmS [H]

Identifier: 156936966

GI number: 156936966

Start: 153739

End: 155517

Strand: Direct

Name: glmS [H]

Synonym: Igni_0171

Alternate gene names: 156936966

Gene position: 153739-155517 (Clockwise)

Preceding gene: 156936963

Following gene: 156936967

Centisome position: 11.85

GC content: 55.42

Gene sequence:

>1779_bases
TTGTGCGGCATTGCCGGCATAGCGGCTAGGGAAGAGTACTACGACGACGTCTTGAAGGAACTAATAAGGTTGCTCGAGTC
CTTGGAGTACAGGGGTTACGACTCCGCCGGGATCGCAGTCTATGACGTAGATTCCAAGAAAATAAGGGTTTGGAAGAAGA
AGGGTAAGGTAGCGGACCTAGTTAAGCTGCTAAGGTCCCAGCTGGGCGACTTCAAGCTCAAGGCCAGCGTGGGCATAGCT
CACACCCGCTGGGCCACGCACGGCGAGCCGAAGGATGAGAACGCGCACCCCCATATTGATTGTGAGGGCAAAGTTGCGGT
CGTCCACAACGGAATAATTTCAAACTACAAAGAGCTCAAGCGAGAGCTCGAGGCGAGGGGTCACTCGTTCAGAAGCGAGA
CGGACACGGAGGTCTTTGCACACCTATTCGAGGAAGAGCTAAAACGTAAGGAACCCTTTGAGGCCTTCAAGGCAGCCGTC
GCACGTCTCGAGGGGTACTACGCAATAGTTGCGATAACTTCCCTCGAGCCGCACAAGGTGTTCTTCGCGCGTAAGGAGAG
CCCCTTAGTGGTGGGAAGGGGGCCTAAAGGGAATTACGTCTCCAGCGACGTCGTCAGCTTGGTGGGCAACTGTTGGGAGG
TATCGCCTTTATACGACGACGACGTAGGGTGGATGAACGATAAGGAGATCTACGTTGAGAGGGGAGGCGTGCGGAGGCGT
TTGAGTTTCATCAAGCCTACATGGAGCCCCGTCCAAGCCCAGAAGGGAAGCTACGAATACTTCATGCTCAAGGAAATACA
CGAGCAACCTCAGGTGGTCAAGGAGACTCTGATATCAATAGCTTCGGAGTGGGACAAGGTGGAGGAGGTCGTAAACCTTC
TCGAAGGCTGGGCGGTGGTGGTCGCCGCCGGCACCTCCTACCACGCCGGCTTGATATTCTCGTATAACGTAATGAAAGAG
ACCGGAAGATATATTCCAGTCATAGACGCCAGCGAGGCGCCCCACTTTTCTAAATTGCTCAAGGGAACGGTCGTAGCTAT
AAGTCAGAGCGGTGAAACGTATGACACCCTCAAGGCCGTGAGGATTGCTAAGGAAAACGGGGCAAAGGTTGTAGGAGTGG
TTAACGTGGTGGGCTCTACCCTAGACAGAGAGGCGGACGTGAGCCTTTACACTAGGGCCGGGCCGGAGATAGGCGTAGCC
GCTACAAAGACCTTCTTAACGCAGTTGAGCGTCTTGAATGCGTTGGTCGCTAGGATGGTCGGGGAGGGCGCGAACAGGGT
AAGGGAGATGGCGAACGAGCTCAGCAAGATAACTAAAGAGAGCATAGAGGTCAGCGCCGGCTACGCTAAGGGGCTTGCCG
ATCAACTGTACACCAAGCGGGACATGTACGTCCTGGGGACGGGGATTTCTTACCCAGTTGCGATGGAAGGTGCATTGAAA
ATTAAAGAGATATCCTACGTCCACGCGGAGGCCTACCCCGCCGGCGAGGCTAAGCACGGTCCCATAGCCTTGGCGGAGCC
GGGTTTCCCCGTCCTCTTAGTCTGGACCCCGGAGGACGTCGAAAAGTTAGAGGTGGCCGAGAAAGAGTTCGAGAGCAGGG
GAAGCGAGGTCTACTGGGTGGCCCCGAGAGGGGACGTCCCGATCCCCGAAGTCGATTGGAAGTACGTCCCCTTTGCCTTG
ACACCGCCCTTGCAGCTGTTGTCGTACTACATGGCAGTTAAGAAGGGCTTGGACCCCGACAAGCCTAGGAACTTGGCGAA
GAGCGTCACAGTTCATTAA

Upstream 100 bases:

>100_bases
GGCACTTCCCGCGCGTTCGGGAGAGCATACCGTTTAAAAATTTTGTGCGACGGGAGAGCGCAAAAACTGAAGGAGGCGAA
AGGCCCTAGGGCCCACTGAC

Downstream 100 bases:

>100_bases
GCTTACTCCAACCTTAATCAGCGCTCCTCCGTAAGTCTGGCGCGGGACTTCAAGGCTTGTTGGAAACAGCTGTCCTAACG
TCTTCCAGCGGAGGCTGCGG

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MCGIAGIAAREEYYDDVLKELIRLLESLEYRGYDSAGIAVYDVDSKKIRVWKKKGKVADLVKLLRSQLGDFKLKASVGIA
HTRWATHGEPKDENAHPHIDCEGKVAVVHNGIISNYKELKRELEARGHSFRSETDTEVFAHLFEEELKRKEPFEAFKAAV
ARLEGYYAIVAITSLEPHKVFFARKESPLVVGRGPKGNYVSSDVVSLVGNCWEVSPLYDDDVGWMNDKEIYVERGGVRRR
LSFIKPTWSPVQAQKGSYEYFMLKEIHEQPQVVKETLISIASEWDKVEEVVNLLEGWAVVVAAGTSYHAGLIFSYNVMKE
TGRYIPVIDASEAPHFSKLLKGTVVAISQSGETYDTLKAVRIAKENGAKVVGVVNVVGSTLDREADVSLYTRAGPEIGVA
ATKTFLTQLSVLNALVARMVGEGANRVREMANELSKITKESIEVSAGYAKGLADQLYTKRDMYVLGTGISYPVAMEGALK
IKEISYVHAEAYPAGEAKHGPIALAEPGFPVLLVWTPEDVEKLEVAEKEFESRGSEVYWVAPRGDVPIPEVDWKYVPFAL
TPPLQLLSYYMAVKKGLDPDKPRNLAKSVTVH

Sequences:

>Translated_592_residues
MCGIAGIAAREEYYDDVLKELIRLLESLEYRGYDSAGIAVYDVDSKKIRVWKKKGKVADLVKLLRSQLGDFKLKASVGIA
HTRWATHGEPKDENAHPHIDCEGKVAVVHNGIISNYKELKRELEARGHSFRSETDTEVFAHLFEEELKRKEPFEAFKAAV
ARLEGYYAIVAITSLEPHKVFFARKESPLVVGRGPKGNYVSSDVVSLVGNCWEVSPLYDDDVGWMNDKEIYVERGGVRRR
LSFIKPTWSPVQAQKGSYEYFMLKEIHEQPQVVKETLISIASEWDKVEEVVNLLEGWAVVVAAGTSYHAGLIFSYNVMKE
TGRYIPVIDASEAPHFSKLLKGTVVAISQSGETYDTLKAVRIAKENGAKVVGVVNVVGSTLDREADVSLYTRAGPEIGVA
ATKTFLTQLSVLNALVARMVGEGANRVREMANELSKITKESIEVSAGYAKGLADQLYTKRDMYVLGTGISYPVAMEGALK
IKEISYVHAEAYPAGEAKHGPIALAEPGFPVLLVWTPEDVEKLEVAEKEFESRGSEVYWVAPRGDVPIPEVDWKYVPFAL
TPPLQLLSYYMAVKKGLDPDKPRNLAKSVTVH
>Mature_592_residues
MCGIAGIAAREEYYDDVLKELIRLLESLEYRGYDSAGIAVYDVDSKKIRVWKKKGKVADLVKLLRSQLGDFKLKASVGIA
HTRWATHGEPKDENAHPHIDCEGKVAVVHNGIISNYKELKRELEARGHSFRSETDTEVFAHLFEEELKRKEPFEAFKAAV
ARLEGYYAIVAITSLEPHKVFFARKESPLVVGRGPKGNYVSSDVVSLVGNCWEVSPLYDDDVGWMNDKEIYVERGGVRRR
LSFIKPTWSPVQAQKGSYEYFMLKEIHEQPQVVKETLISIASEWDKVEEVVNLLEGWAVVVAAGTSYHAGLIFSYNVMKE
TGRYIPVIDASEAPHFSKLLKGTVVAISQSGETYDTLKAVRIAKENGAKVVGVVNVVGSTLDREADVSLYTRAGPEIGVA
ATKTFLTQLSVLNALVARMVGEGANRVREMANELSKITKESIEVSAGYAKGLADQLYTKRDMYVLGTGISYPVAMEGALK
IKEISYVHAEAYPAGEAKHGPIALAEPGFPVLLVWTPEDVEKLEVAEKEFESRGSEVYWVAPRGDVPIPEVDWKYVPFAL
TPPLQLLSYYMAVKKGLDPDKPRNLAKSVTVH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=688, Percent_Identity=33.5755813953488, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=32.7510917030568, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1790167, Length=620, Percent_Identity=39.1935483870968, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788651, Length=211, Percent_Identity=31.7535545023697, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082251, Length=245, Percent_Identity=21.2244897959184, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=440, Percent_Identity=31.8181818181818, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17532899, Length=431, Percent_Identity=31.322505800464, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17532897, Length=436, Percent_Identity=30.9633027522936, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322745, Length=459, Percent_Identity=32.244008714597, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=27.1461716937355, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.7647058823529, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357745, Length=691, Percent_Identity=33.1403762662808, Blast_Score=298, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65730; Mature: 65730

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIAGIAAREEYYDDVLKELIRLLESLEYRGYDSAGIAVYDVDSKKIRVWKKKGKVADL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEHHCCCHHHH
VKLLRSQLGDFKLKASVGIAHTRWATHGEPKDENAHPHIDCEGKVAVVHNGIISNYKELK
HHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
RELEARGHSFRSETDTEVFAHLFEEELKRKEPFEAFKAAVARLEGYYAIVAITSLEPHKV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEE
FFARKESPLVVGRGPKGNYVSSDVVSLVGNCWEVSPLYDDDVGWMNDKEIYVERGGVRRR
EEEECCCCEEEECCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEECCCHHHH
LSFIKPTWSPVQAQKGSYEYFMLKEIHEQPQVVKETLISIASEWDKVEEVVNLLEGWAVV
HHHHCCCCCCHHCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAAGTSYHAGLIFSYNVMKETGRYIPVIDASEAPHFSKLLKGTVVAISQSGETYDTLKAV
EEECCCCCCEEEEEEHHHHHCCCEEEEEECCCCCHHHHHHCCEEEEEECCCCHHHHHHHH
RIAKENGAKVVGVVNVVGSTLDREADVSLYTRAGPEIGVAATKTFLTQLSVLNALVARMV
HHHHCCCCEEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GEGANRVREMANELSKITKESIEVSAGYAKGLADQLYTKRDMYVLGTGISYPVAMEGALK
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCEE
IKEISYVHAEAYPAGEAKHGPIALAEPGFPVLLVWTPEDVEKLEVAEKEFESRGSEVYWV
EEHEEEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE
APRGDVPIPEVDWKYVPFALTPPLQLLSYYMAVKKGLDPDKPRNLAKSVTVH
CCCCCCCCCCCCCEEECEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIAGIAAREEYYDDVLKELIRLLESLEYRGYDSAGIAVYDVDSKKIRVWKKKGKVADL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEHHCCCHHHH
VKLLRSQLGDFKLKASVGIAHTRWATHGEPKDENAHPHIDCEGKVAVVHNGIISNYKELK
HHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
RELEARGHSFRSETDTEVFAHLFEEELKRKEPFEAFKAAVARLEGYYAIVAITSLEPHKV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEE
FFARKESPLVVGRGPKGNYVSSDVVSLVGNCWEVSPLYDDDVGWMNDKEIYVERGGVRRR
EEEECCCCEEEECCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEECCCHHHH
LSFIKPTWSPVQAQKGSYEYFMLKEIHEQPQVVKETLISIASEWDKVEEVVNLLEGWAVV
HHHHCCCCCCHHCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAAGTSYHAGLIFSYNVMKETGRYIPVIDASEAPHFSKLLKGTVVAISQSGETYDTLKAV
EEECCCCCCEEEEEEHHHHHCCCEEEEEECCCCCHHHHHHCCEEEEEECCCCHHHHHHHH
RIAKENGAKVVGVVNVVGSTLDREADVSLYTRAGPEIGVAATKTFLTQLSVLNALVARMV
HHHHCCCCEEEEHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GEGANRVREMANELSKITKESIEVSAGYAKGLADQLYTKRDMYVLGTGISYPVAMEGALK
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCEE
IKEISYVHAEAYPAGEAKHGPIALAEPGFPVLLVWTPEDVEKLEVAEKEFESRGSEVYWV
EEHEEEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEE
APRGDVPIPEVDWKYVPFALTPPLQLLSYYMAVKKGLDPDKPRNLAKSVTVH
CCCCCCCCCCCCCEEECEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA