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The map label for this gene is moaB [H]

Identifier: 156936806

GI number: 156936806

Start: 10984

End: 11508

Strand: Direct

Name: moaB [H]

Synonym: Igni_0011

Alternate gene names: 156936806

Gene position: 10984-11508 (Clockwise)

Preceding gene: 156936803

Following gene: 156936807

Centisome position: 0.85

GC content: 56.19

Gene sequence:

>525_bases
ATGCACGAGCACGAACGCTTCGGGCCGGAAAGGGTCCGCTTCGGCATAGTAGTAGTCTCGGATGCAGTTTATGAAGGGCG
CAGAGAGGACGTCAGCGGCAAGTTGGCCAAAAAGATTATTACTGAGAGTGGCCACGAGGTAACGTATTTCTCACTCATAC
CCAACGATAAAGGAGCCATCCTCAACGTCCTCGAAGAAGCCAAGGAATCGCCAGTAGACGTGATCGTATTTGTGGGGGGC
ACGGGATTGGGACCCAACGACCTAACGGTAGACGTCGTCGACCGAGTGGCCGACAAGGAGGTGCCGGGCTTCGGCGAGCT
CTTCAGATACATCACGTTTCAAAAGAGGGGATCCATAGCCATCCTCACGAGGGCTGGCTTGTGGGTCTACTCGAAACTGC
TCATATTGGTCACGCCGGGAAGCCCCGACGCAGTAGAGACTGCCCTTCAACTATTCTTGCCCGTAGCGAGACACGCCGTA
GCGGAGGCGAGGGGACTGCGCCATGGCATGCCCAAAGGAGTTTGA

Upstream 100 bases:

>100_bases
CTCGTCGTCTTCGACCCTCTCCTCGTCTTCCTCAGCCACTATTTCGGCCTCGTGAACTTCATTTTCTTCCATCATCCGAG
CCACCTCGGAGAGCGATAAG

Downstream 100 bases:

>100_bases
ATACCTTCCACACACTGCAGACATCATTGTGGTAGGCTATGGAGAAACTCTGGAAGAGGCGTTCGCTAATGCAGCCAAGG
GAGTTTTCAACATAATTACT

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MHEHERFGPERVRFGIVVVSDAVYEGRREDVSGKLAKKIITESGHEVTYFSLIPNDKGAILNVLEEAKESPVDVIVFVGG
TGLGPNDLTVDVVDRVADKEVPGFGELFRYITFQKRGSIAILTRAGLWVYSKLLILVTPGSPDAVETALQLFLPVARHAV
AEARGLRHGMPKGV

Sequences:

>Translated_174_residues
MHEHERFGPERVRFGIVVVSDAVYEGRREDVSGKLAKKIITESGHEVTYFSLIPNDKGAILNVLEEAKESPVDVIVFVGG
TGLGPNDLTVDVVDRVADKEVPGFGELFRYITFQKRGSIAILTRAGLWVYSKLLILVTPGSPDAVETALQLFLPVARHAV
AEARGLRHGMPKGV
>Mature_174_residues
MHEHERFGPERVRFGIVVVSDAVYEGRREDVSGKLAKKIITESGHEVTYFSLIPNDKGAILNVLEEAKESPVDVIVFVGG
TGLGPNDLTVDVVDRVADKEVPGFGELFRYITFQKRGSIAILTRAGLWVYSKLLILVTPGSPDAVETALQLFLPVARHAV
AEARGLRHGMPKGV

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=163, Percent_Identity=26.3803680981595, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI10880983, Length=163, Percent_Identity=26.3803680981595, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1787000, Length=140, Percent_Identity=32.8571428571429, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17136978, Length=155, Percent_Identity=29.6774193548387, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24638841, Length=155, Percent_Identity=29.6774193548387, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19005; Mature: 19005

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEHERFGPERVRFGIVVVSDAVYEGRREDVSGKLAKKIITESGHEVTYFSLIPNDKGAI
CCCCHHCCCCCEEEEEEEEECHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LNVLEEAKESPVDVIVFVGGTGLGPNDLTVDVVDRVADKEVPGFGELFRYITFQKRGSIA
HHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEE
ILTRAGLWVYSKLLILVTPGSPDAVETALQLFLPVARHAVAEARGLRHGMPKGV
EEECCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHEHERFGPERVRFGIVVVSDAVYEGRREDVSGKLAKKIITESGHEVTYFSLIPNDKGAI
CCCCHHCCCCCEEEEEEEEECHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
LNVLEEAKESPVDVIVFVGGTGLGPNDLTVDVVDRVADKEVPGFGELFRYITFQKRGSIA
HHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEE
ILTRAGLWVYSKLLILVTPGSPDAVETALQLFLPVARHAVAEARGLRHGMPKGV
EEECCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]