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The map label for this gene is aroA [H]

Identifier: 154687115

GI number: 154687115

Start: 2812974

End: 2814050

Strand: Reverse

Name: aroA [H]

Synonym: RBAM_026870

Alternate gene names: 154687115

Gene position: 2814050-2812974 (Counterclockwise)

Preceding gene: 154687116

Following gene: 154687114

Centisome position: 71.81

GC content: 47.63

Gene sequence:

>1077_bases
ATGAGCAACAAGGAATTAGAGAGCCTAAGACAGCAGGCAGACGCACTAAACTTAGAAATCCTTAAATTAATCAATGAACG
CGGAGCCGTTGTAAAAGAAATCGGTAAAGCAAAGGAAGCACAGGGTGTCAACCGATTTGACCCTGTCAGAGAGCGTACAA
TGCTTAACCGCATTATTGAAAGCAATGACGGCCCATTTGAAAACTCAACGATCCAGCATATTTTCAAAGAAATTTTCAAA
GCCGGACTTGAACTTCAAGAAGAGGATCACAGCAAAGCGTTGCTCGTCTCCCGGAAGAAAAAAGCAGAAGATACGATCGT
TGATATTAAAGGTGAAAAAATCGGTGACGGCGATCAGAGATTCATCGTCGGACCTTGTGCCGTAGAAAGCTATGAGCAGG
TTGCCGAAGTAGCGGCCGCAGCGAAAAAACAAGGCATTAAAATCCTGCGCGGGGGCGCGTTTAAACCCCGCACAAGTCCG
TATGATTTCCAAGGTCTCGGCGTAGAAGGCCTGCAAATTCTTAAACGCGTCGCTGATGAATATGACCTCGCGGTGATCAG
TGAAATCGTAACGCCCGCCCACATTGAGCAAGCGATTGATTACATTGACGTCATTCAGATCGGCGCGCGGAACATGCAAA
ACTTTGAATTGCTGAAAGCCGCCGGTTCCGTTAAAAAGCCGGTATTGTTAAAACGCGGTCTTGCCGCAACAATTTCAGAG
TTCATCAATGCAGCTGAATACATCATGTCACAAGGAAACGACCAAATCATTCTTTGTGAGCGCGGAATCAGAACGTACGA
AACGGCAACGAGAAACACACTCGACATTTCTGCCGTGCCGATTTTGAAACAGGAAACTCACTTGCCGGTGTTTGTTGACG
TCACACACTCAACAGGCCGCCGCGATCTCCTGCTTCCGACAGCAAAAGCGGCGCTTGCGATCGGCGCTGACGGCGTGATG
GCCGAAGTTCACCCTGATCCTTCCGTTGCCCTTTCAGACTCTGCGCAGCAGATGGATATACCTGAATTCGAGAAATGGCT
GAACGAATTAAAGCCAATGCTGAAAGTAAAAGCATAA

Upstream 100 bases:

>100_bases
TGTGAAAAAATTTATTATTTCATATTCCTATTTTCGCATAACTGTAGTAAGATGCATGTTAACCATTAAAATAAAACATA
GCATAGAAGGGATGAAAAAG

Downstream 100 bases:

>100_bases
TACAACGTTCCGCTCTTTAAAGGCCGCCTCGCGCGGCTTTTTTTCGTATCTTCATTTTATTTAATTATAAAATGAAAGTG
AACGTTTTCATCACTGGGAA

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSNKELESLRQQADALNLEILKLINERGAVVKEIGKAKEAQGVNRFDPVRERTMLNRIIESNDGPFENSTIQHIFKEIFK
AGLELQEEDHSKALLVSRKKKAEDTIVDIKGEKIGDGDQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSP
YDFQGLGVEGLQILKRVADEYDLAVISEIVTPAHIEQAIDYIDVIQIGARNMQNFELLKAAGSVKKPVLLKRGLAATISE
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVM
AEVHPDPSVALSDSAQQMDIPEFEKWLNELKPMLKVKA

Sequences:

>Translated_358_residues
MSNKELESLRQQADALNLEILKLINERGAVVKEIGKAKEAQGVNRFDPVRERTMLNRIIESNDGPFENSTIQHIFKEIFK
AGLELQEEDHSKALLVSRKKKAEDTIVDIKGEKIGDGDQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSP
YDFQGLGVEGLQILKRVADEYDLAVISEIVTPAHIEQAIDYIDVIQIGARNMQNFELLKAAGSVKKPVLLKRGLAATISE
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVM
AEVHPDPSVALSDSAQQMDIPEFEKWLNELKPMLKVKA
>Mature_357_residues
SNKELESLRQQADALNLEILKLINERGAVVKEIGKAKEAQGVNRFDPVRERTMLNRIIESNDGPFENSTIQHIFKEIFKA
GLELQEEDHSKALLVSRKKKAEDTIVDIKGEKIGDGDQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPY
DFQGLGVEGLQILKRVADEYDLAVISEIVTPAHIEQAIDYIDVIQIGARNMQNFELLKAAGSVKKPVLLKRGLAATISEF
INAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVMA
EVHPDPSVALSDSAQQMDIPEFEKWLNELKPMLKVKA

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=209, Percent_Identity=26.7942583732057, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 39520; Mature: 39389

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKELESLRQQADALNLEILKLINERGAVVKEIGKAKEAQGVNRFDPVRERTMLNRIIE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SNDGPFENSTIQHIFKEIFKAGLELQEEDHSKALLVSRKKKAEDTIVDIKGEKIGDGDQR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCE
FIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPYDFQGLGVEGLQILKRVADE
EEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YDLAVISEIVTPAHIEQAIDYIDVIQIGARNMQNFELLKAAGSVKKPVLLKRGLAATISE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHH
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADGVMAEVHPDPSVALSDSAQQMDIPEFEKWLNELKPMLKVKA
CCEECCHHHHHHEECCCCCEEEECCCCCEEECCCCHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNKELESLRQQADALNLEILKLINERGAVVKEIGKAKEAQGVNRFDPVRERTMLNRIIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SNDGPFENSTIQHIFKEIFKAGLELQEEDHSKALLVSRKKKAEDTIVDIKGEKIGDGDQR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCE
FIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPYDFQGLGVEGLQILKRVADE
EEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YDLAVISEIVTPAHIEQAIDYIDVIQIGARNMQNFELLKAAGSVKKPVLLKRGLAATISE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHH
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADGVMAEVHPDPSVALSDSAQQMDIPEFEKWLNELKPMLKVKA
CCEECCHHHHHHEECCCCCEEEECCCCCEEECCCCHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]