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The map label for this gene is sppA [H]

Identifier: 154687074

GI number: 154687074

Start: 2772777

End: 2773784

Strand: Reverse

Name: sppA [H]

Synonym: RBAM_026460

Alternate gene names: 154687074

Gene position: 2773784-2772777 (Counterclockwise)

Preceding gene: 154687076

Following gene: 154687073

Centisome position: 70.79

GC content: 47.32

Gene sequence:

>1008_bases
ATGAATGCAAAAAGATGGATTGCGCTCGTCATCGCGCTCGGCATTTTCGGCGTATCAGTCATTGCAAGTGTGACCGTCGG
GGTGCTGAAGAATATCGGAGATACAGGGTCTGACTTTGCATCACTGACAGATGACACAGAGGAAGTGACGCTGGATAAGG
GCAGCCCCGGCAGTAAAATCGCCGTGCTTGAAGTGGACGGCACGATTGAGGATAACGGCGGGTCCGCTGGCCTGCTCAGC
TCAGGCGGGTATGATCACAGATCATTTTTAAAACAGGTTGAGCGTGCGAAAGAAGACAAAAGCGTCAAAGGAATTGTGCT
GAAAATCAATTCCCCTGGCGGAGGCGTGTACGAAAGCGCGGAAATACATAAAAAACTGGAAGAACTAAAGAAAGAAACGA
AGAAACCGATTTATGTATCCATGGGCTCCATGGCGGCATCGGGAGGCTACTATATTTCAACGGCCGCCGATAAAATCTAT
GCTTCACCGGAAACGCTCACGGGTTCACTGGGCGTCATCATGGAAAGCGTCAATTATTCCAAGCTCGCCGATGAACTCGG
CATCAAGTTTGAAACCATTAAAAGCGGCGCGCATAAAGACATCATGTCCCCGACCCGCGACATGACGAAGGAAGAAAGAA
AGATCATGCAGACAATGGTCAACGATTCTTATGAAGGATTTGTCAATGTCATTTCAAAAGGCCGGCACATGTCAAAAGCG
GATGTGAAAAAAATTGCCGACGGCCGTGTTTACGACGGCAGACAAGCGAAAAAAATCGGCCTCGTTGATGACCTCGGTTT
TTACGATGACACGATCAGCGCGATGAAAAAGGACCATAAAAATATGAAAAACGCTTCAGTCATCACATACGAGGAAGGAT
TCGGATTAGGCTCGCTCTTTTCCATGAGCGCAGCGAAAATGTTTAAAAGCGAAATTGATTTTCTGAATATGAAAGAACTC
ATTTCGCAATCCGGTTCGCCGCGGATGATGTATCTCTATGCAAAGTAG

Upstream 100 bases:

>100_bases
ATGTTTCCTGTTTATCCGTTAAGGGAAAGCGCTTCATGAAAAAAATGAATCTTTTTTTACGGGGGAACGTACGAATATTG
ACAGAAAAGGAGGAGAACAA

Downstream 100 bases:

>100_bases
GGGGGAAGAAAGAATGGACGCGACTTACGAAGGCTTTCACGGCAAAGAAGAGGAAGCCGAGCAACAGAGGGCGCCCGAGC
AGGCATATGCGGGCTTTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNAKRWIALVIALGIFGVSVIASVTVGVLKNIGDTGSDFASLTDDTEEVTLDKGSPGSKIAVLEVDGTIEDNGGSAGLLS
SGGYDHRSFLKQVERAKEDKSVKGIVLKINSPGGGVYESAEIHKKLEELKKETKKPIYVSMGSMAASGGYYISTAADKIY
ASPETLTGSLGVIMESVNYSKLADELGIKFETIKSGAHKDIMSPTRDMTKEERKIMQTMVNDSYEGFVNVISKGRHMSKA
DVKKIADGRVYDGRQAKKIGLVDDLGFYDDTISAMKKDHKNMKNASVITYEEGFGLGSLFSMSAAKMFKSEIDFLNMKEL
ISQSGSPRMMYLYAK

Sequences:

>Translated_335_residues
MNAKRWIALVIALGIFGVSVIASVTVGVLKNIGDTGSDFASLTDDTEEVTLDKGSPGSKIAVLEVDGTIEDNGGSAGLLS
SGGYDHRSFLKQVERAKEDKSVKGIVLKINSPGGGVYESAEIHKKLEELKKETKKPIYVSMGSMAASGGYYISTAADKIY
ASPETLTGSLGVIMESVNYSKLADELGIKFETIKSGAHKDIMSPTRDMTKEERKIMQTMVNDSYEGFVNVISKGRHMSKA
DVKKIADGRVYDGRQAKKIGLVDDLGFYDDTISAMKKDHKNMKNASVITYEEGFGLGSLFSMSAAKMFKSEIDFLNMKEL
ISQSGSPRMMYLYAK
>Mature_335_residues
MNAKRWIALVIALGIFGVSVIASVTVGVLKNIGDTGSDFASLTDDTEEVTLDKGSPGSKIAVLEVDGTIEDNGGSAGLLS
SGGYDHRSFLKQVERAKEDKSVKGIVLKINSPGGGVYESAEIHKKLEELKKETKKPIYVSMGSMAASGGYYISTAADKIY
ASPETLTGSLGVIMESVNYSKLADELGIKFETIKSGAHKDIMSPTRDMTKEERKIMQTMVNDSYEGFVNVISKGRHMSKA
DVKKIADGRVYDGRQAKKIGLVDDLGFYDDTISAMKKDHKNMKNASVITYEEGFGLGSLFSMSAAKMFKSEIDFLNMKEL
ISQSGSPRMMYLYAK

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=217, Percent_Identity=36.405529953917, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787527, Length=171, Percent_Identity=28.6549707602339, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 36349; Mature: 36349

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKRWIALVIALGIFGVSVIASVTVGVLKNIGDTGSDFASLTDDTEEVTLDKGSPGSKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHEEECCCCCCCEE
AVLEVDGTIEDNGGSAGLLSSGGYDHRSFLKQVERAKEDKSVKGIVLKINSPGGGVYESA
EEEEECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHH
EIHKKLEELKKETKKPIYVSMGSMAASGGYYISTAADKIYASPETLTGSLGVIMESVNYS
HHHHHHHHHHHHHCCCEEEEECCEECCCCEEEEECCHHHCCCCCHHCCHHHHHHHHCCHH
KLADELGIKFETIKSGAHKDIMSPTRDMTKEERKIMQTMVNDSYEGFVNVISKGRHMSKA
HHHHHHCCEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
DVKKIADGRVYDGRQAKKIGLVDDLGFYDDTISAMKKDHKNMKNASVITYEEGFGLGSLF
HHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
SMSAAKMFKSEIDFLNMKELISQSGSPRMMYLYAK
HHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MNAKRWIALVIALGIFGVSVIASVTVGVLKNIGDTGSDFASLTDDTEEVTLDKGSPGSKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHEEECCCCCCCEE
AVLEVDGTIEDNGGSAGLLSSGGYDHRSFLKQVERAKEDKSVKGIVLKINSPGGGVYESA
EEEEECCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHH
EIHKKLEELKKETKKPIYVSMGSMAASGGYYISTAADKIYASPETLTGSLGVIMESVNYS
HHHHHHHHHHHHHCCCEEEEECCEECCCCEEEEECCHHHCCCCCHHCCHHHHHHHHCCHH
KLADELGIKFETIKSGAHKDIMSPTRDMTKEERKIMQTMVNDSYEGFVNVISKGRHMSKA
HHHHHHCCEEEHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
DVKKIADGRVYDGRQAKKIGLVDDLGFYDDTISAMKKDHKNMKNASVITYEEGFGLGSLF
HHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
SMSAAKMFKSEIDFLNMKELISQSGSPRMMYLYAK
HHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]