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The map label for this gene is uvrC

Identifier: 154686983

GI number: 154686983

Start: 2674535

End: 2676307

Strand: Reverse

Name: uvrC

Synonym: RBAM_025550

Alternate gene names: 154686983

Gene position: 2676307-2674535 (Counterclockwise)

Preceding gene: 154686984

Following gene: 154686982

Centisome position: 68.3

GC content: 47.21

Gene sequence:

>1773_bases
ATGAATAAACAACTGAAAGAAAAGCTGGCCCTCCTTCCCGATCAGCCGGGCTGTTATTTAATGAAAGACCGTCAAAAAAC
AGTCATCTACGTGGGGAAAGCGAAAGTCTTGAAAAACAGGGTGCGATCTTATTTCACCGGTTCTCACGACGCAAAAACCC
AACGGCTTGTGTCGGAGATTGAGGACTTTGAATATATCGTGACTTCCTCCAATCTTGAAGCGCTTATTTTGGAAATGAAT
CTGATTAAAAAATACGATCCGAAATACAATGTCATGCTGAAAGATGATAAAACCTATCCCTTTATTAAAATCACCCATGA
ACGCCATCCGCGGCTGATTGTCACCCGGAATGTCAAAAAAGACAAAGGACGCTATTTCGGCCCGTATCCGAATGTGCAGG
CGGCGCGGGAAACGAAAAAACTGCTGGACCGCCTTTACCCGCTCAGGAAATGCTCAAAGCTTCCGGACCGCGTCTGTCTC
TATTATCATCTCGGACAATGCCTTGCCCCATGTGTAAAGGATATATCTGAGGAGACAAACCGCGAGATTGTTGAAGACAT
TACCCGTTTTTTAAAGGGAGGGCATAACGAAATCAAAAAAGAGCTCGAAGCGAAAATGGCAGAAGCGGCGGAAAAGCTTG
AATTTGAACGGGCTAAAGAATTCCGCGACCAGCTTGCTCACATCGAATCGACGATGGAGAAGCAAAAAATGACCATGAAT
GACCTTCTGGACCGCGATGTGTTTGCATATGCCTACGATAAAGGCTGGATGTGCGTCCAAGTCTTTTTCATACGCCAAGG
AAAACTGATCGAACGCGACGTCAGCATGTTTCCGATGTATCAGGAAGCGGATGAAGAATTTCTGACCTTCATCGGCCAGT
TCTACTCTAAAAACAATCACTTTCTGCCTAAGGAAATTCTGGTGCCTGACAGCGTTGACAGGGACATGATCACCGAGCTG
TTGGAAACCGCCGTGCATCAGCCGAAAAAAGGCCCGAAAAAAGAGCTGCTTTTGCTTGCGCACAAAAATGCGAAAATCGC
TCTGCGGGAAAAATTCTCGTTAATCGAGCGGGATGAGGAACGGTCAATCGGTGCAGCCGAACGGCTCGGCGAAGCGCTGA
ATATTTATACGCCGCATCGGATTGAAGCGTTTGACAACTCCAATATTCAAGGCACAAACCCCGTATCGGCCATGATCGTC
TTTATTGACGGAAAACCGAATAAAAAGGAATACCGCAAATATAAAATTAAAACCGTAACAGGGCCGGATGATTACGGCTC
AATGAGGGAAGTCGTCAGAAGAAGGTACACGAGGGTGCTCCGCGAAAATCTTCCGCTGCCGGATTTAATCATCATTGACG
GCGGAAAAGGGCAGATTAACGCGGCGCGCGACGTGCTTGAGAATGAGCTCGGCCTTGATGTCCCGGTAGCGGGATTGGCG
AAAGATGATAAACACCGAACATCCAACCTTTTGATCGGCGACCCGCTTGAACCGGTGTTTCTGGAGCGGAACAGCCAAGA
GTTTTACCTGCTTCAGCGCATTCAGGACGAAGTTCACCGTTTTGCGATCAGCTTTCACAGACAGATCCGGGGAAAAAGCG
TCTTTCAATCCGTTCTGGATGATATCCCCGGAATCGGCGAAAAACGCAAAAAAATGCTCTTAAAACATTTCGGATCTGTC
AAAAAGATGAAGGAAGCAAGCCTTGACGATATCAAAAAAGCGGGTGTGCCGGCCGCGGCGGCCCAGCTGCTGTTTGAAAA
ATTAAAAAAATAG

Upstream 100 bases:

>100_bases
ATCGCCTTTTTTTGATCTTCCAAAAGCTGAGAATGGAGAAAAACAAATGTTCGTGATACACTGAATGGACACGAGAAATG
AATGTAAGGAAGGGTAACGT

Downstream 100 bases:

>100_bases
TATTGTGCTTTTCTGAAAAATCTGCTAGAATGTGAACTAATTTCATAAGATCGTGTTATATGGTGAAGATAGAGGTGCGA
ACTTCAATAGTAAGCCTTTG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MNKQLKEKLALLPDQPGCYLMKDRQKTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVSEIEDFEYIVTSSNLEALILEMN
LIKKYDPKYNVMLKDDKTYPFIKITHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL
YYHLGQCLAPCVKDISEETNREIVEDITRFLKGGHNEIKKELEAKMAEAAEKLEFERAKEFRDQLAHIESTMEKQKMTMN
DLLDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPMYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSVDRDMITEL
LETAVHQPKKGPKKELLLLAHKNAKIALREKFSLIERDEERSIGAAERLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIV
FIDGKPNKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVLENELGLDVPVAGLA
KDDKHRTSNLLIGDPLEPVFLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSVFQSVLDDIPGIGEKRKKMLLKHFGSV
KKMKEASLDDIKKAGVPAAAAQLLFEKLKK

Sequences:

>Translated_590_residues
MNKQLKEKLALLPDQPGCYLMKDRQKTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVSEIEDFEYIVTSSNLEALILEMN
LIKKYDPKYNVMLKDDKTYPFIKITHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL
YYHLGQCLAPCVKDISEETNREIVEDITRFLKGGHNEIKKELEAKMAEAAEKLEFERAKEFRDQLAHIESTMEKQKMTMN
DLLDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPMYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSVDRDMITEL
LETAVHQPKKGPKKELLLLAHKNAKIALREKFSLIERDEERSIGAAERLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIV
FIDGKPNKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVLENELGLDVPVAGLA
KDDKHRTSNLLIGDPLEPVFLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSVFQSVLDDIPGIGEKRKKMLLKHFGSV
KKMKEASLDDIKKAGVPAAAAQLLFEKLKK
>Mature_590_residues
MNKQLKEKLALLPDQPGCYLMKDRQKTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVSEIEDFEYIVTSSNLEALILEMN
LIKKYDPKYNVMLKDDKTYPFIKITHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL
YYHLGQCLAPCVKDISEETNREIVEDITRFLKGGHNEIKKELEAKMAEAAEKLEFERAKEFRDQLAHIESTMEKQKMTMN
DLLDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPMYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSVDRDMITEL
LETAVHQPKKGPKKELLLLAHKNAKIALREKFSLIERDEERSIGAAERLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIV
FIDGKPNKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVLENELGLDVPVAGLA
KDDKHRTSNLLIGDPLEPVFLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSVFQSVLDDIPGIGEKRKKMLLKHFGSV
KKMKEASLDDIKKAGVPAAAAQLLFEKLKK

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=619, Percent_Identity=38.4491114701131, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_BACA2 (A7Z7D7)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422144.1
- ProteinModelPortal:   A7Z7D7
- STRING:   A7Z7D7
- EnsemblBacteria:   EBBACT00000004402
- GeneID:   5460302
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_025550
- eggNOG:   COG0322
- GeneTree:   EBGT00050000001864
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- ProtClustDB:   PRK00558
- BioCyc:   BAMY326423:RBAM_025550-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- SMART:   SM00278
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 68343; Mature: 68343

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQLKEKLALLPDQPGCYLMKDRQKTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVSEI
CCHHHHHHHHCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EDFEYIVTSSNLEALILEMNLIKKYDPKYNVMLKDDKTYPFIKITHERHPRLIVTRNVKK
HHHEEEEECCCHHEEHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCC
DKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYHLGQCLAPCVKDISEETN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
REIVEDITRFLKGGHNEIKKELEAKMAEAAEKLEFERAKEFRDQLAHIESTMEKQKMTMN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPMYQEADEEFLTFIGQFYSKNNH
HHHHHHHHEEEECCCCEEEEEEHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
FLPKEILVPDSVDRDMITELLETAVHQPKKGPKKELLLLAHKNAKIALREKFSLIERDEE
CCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEHHHHHHHHHCCHH
RSIGAAERLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIVFIDGKPNKKEYRKYKIKTVT
CCCCHHHHHCCHHCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHEEEEEEEC
GPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVLENELGLDVPVAGLA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
KDDKHRTSNLLIGDPLEPVFLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSVFQSVLD
CCCCCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIPGIGEKRKKMLLKHFGSVKKMKEASLDDIKKAGVPAAAAQLLFEKLKK
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKQLKEKLALLPDQPGCYLMKDRQKTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVSEI
CCHHHHHHHHCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EDFEYIVTSSNLEALILEMNLIKKYDPKYNVMLKDDKTYPFIKITHERHPRLIVTRNVKK
HHHEEEEECCCHHEEHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCC
DKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYHLGQCLAPCVKDISEETN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
REIVEDITRFLKGGHNEIKKELEAKMAEAAEKLEFERAKEFRDQLAHIESTMEKQKMTMN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPMYQEADEEFLTFIGQFYSKNNH
HHHHHHHHEEEECCCCEEEEEEHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
FLPKEILVPDSVDRDMITELLETAVHQPKKGPKKELLLLAHKNAKIALREKFSLIERDEE
CCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEHHHHHHHHHCCHH
RSIGAAERLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIVFIDGKPNKKEYRKYKIKTVT
CCCCHHHHHCCHHCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHEEEEEEEC
GPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVLENELGLDVPVAGLA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
KDDKHRTSNLLIGDPLEPVFLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSVFQSVLD
CCCCCCCCCEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIPGIGEKRKKMLLKHFGSVKKMKEASLDDIKKAGVPAAAAQLLFEKLKK
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA