Click here to switch to the map view.

The map label for this gene is racE

Identifier: 154686974

GI number: 154686974

Start: 2666691

End: 2667509

Strand: Reverse

Name: racE

Synonym: RBAM_025460

Alternate gene names: 154686974

Gene position: 2667509-2666691 (Counterclockwise)

Preceding gene: 154686975

Following gene: 154686973

Centisome position: 68.07

GC content: 48.84

Gene sequence:

>819_bases
TTGTTGGAACAGCCGATAGGAGTCATTGATTCCGGGGTTGGCGGGTTAACCGTTGCTAAGGAAATCATGAGACAGCTACC
GAAGGAAAATATCATCTATGTGGGAGATACAAAACGCTGCCCGTACGGCCCGCGTCCTGAAGAAGAAGTTCTTCAATACA
CGTGGGAAATGACCGATTACCTGCTGGAAAACCACCATATCAAAATGCTCGTGATCGCCTGCAATACGGCCACGGCCATT
GCCTTGGAGGATATTCAGCGCAAAACGGATATTCCGGTTGTCGGCGTCATTCAGCCGGGTGCAAGAACGGCGATAAAGGT
CACGAAAAACCAGCATATCGGCGTCATCGGCACGGTCAATACCATTAAAAGCAGAGCGTATGAGCAGGCGCTGCTCGGGT
TAAACGCAGAACTTCAAGTTGAGAACACGGCTTGTCCGCTGCTCGTGCCGTTTGTGGAAAGCGGACGGTTTCTTCAGGAA
TCAGCGGAGGAAGCGGTTGAAGCATCGCTTGAGCCTTTAAAAGGTACATCAATTGACACCTTGATTTTAGGATGTACGCA
TTATCCGATTTTAAAAGATCCGATTCAGAACTATATGGGAGAGCATGTGAAAATCATTTCCTCCGGAGACGAGACGGCGA
GAGAAGTGAGCACCATTTTGTCTTATAAAGGTTTGTTAAACCAATCGAAACATGCACCGGAGCATCAATTTCTTACAACG
GGGGAGCGGAACGGCTTCGCAAAAATTGCCGAAGACTGGTTCGGCCACGAAATCGGCCATGTCGAGTGCATCTCCCTTCA
AGAGCCGGTCAGAAAATAA

Upstream 100 bases:

>100_bases
TTGCGGGATATGTTTGCGACATTTTCCGAAGAAGAAACAGCCGCTTTCGAAAAATCATTATTGAAACTGCAGCATGAAAT
GAAAAGAAAATGAGGCGATT

Downstream 100 bases:

>100_bases
ATCAAAAAACCCGCTGTTTACGGCGGGTTTTTTTGCGCTTCCCGGTCTATTTCCCGGACAGGGCTCGTATACATCATAGT
ACAAACAGCCTTAGGAGGGA

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWEMTDYLLENHHIKMLVIACNTATAI
ALEDIQRKTDIPVVGVIQPGARTAIKVTKNQHIGVIGTVNTIKSRAYEQALLGLNAELQVENTACPLLVPFVESGRFLQE
SAEEAVEASLEPLKGTSIDTLILGCTHYPILKDPIQNYMGEHVKIISSGDETAREVSTILSYKGLLNQSKHAPEHQFLTT
GERNGFAKIAEDWFGHEIGHVECISLQEPVRK

Sequences:

>Translated_272_residues
MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWEMTDYLLENHHIKMLVIACNTATAI
ALEDIQRKTDIPVVGVIQPGARTAIKVTKNQHIGVIGTVNTIKSRAYEQALLGLNAELQVENTACPLLVPFVESGRFLQE
SAEEAVEASLEPLKGTSIDTLILGCTHYPILKDPIQNYMGEHVKIISSGDETAREVSTILSYKGLLNQSKHAPEHQFLTT
GERNGFAKIAEDWFGHEIGHVECISLQEPVRK
>Mature_272_residues
MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWEMTDYLLENHHIKMLVIACNTATAI
ALEDIQRKTDIPVVGVIQPGARTAIKVTKNQHIGVIGTVNTIKSRAYEQALLGLNAELQVENTACPLLVPFVESGRFLQE
SAEEAVEASLEPLKGTSIDTLILGCTHYPILKDPIQNYMGEHVKIISSGDETAREVSTILSYKGLLNQSKHAPEHQFLTT
GERNGFAKIAEDWFGHEIGHVECISLQEPVRK

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=228, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_BACA2 (A7Z7C8)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422135.1
- ProteinModelPortal:   A7Z7C8
- SMR:   A7Z7C8
- STRING:   A7Z7C8
- EnsemblBacteria:   EBBACT00000005236
- GeneID:   5461586
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_025460
- eggNOG:   COG0796
- GeneTree:   EBGT00050000002346
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- ProtClustDB:   PRK00865
- BioCyc:   BAMY326423:RBAM_025460-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 30095; Mature: 30095

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWEMTDY
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLENHHIKMLVIACNTATAIALEDIQRKTDIPVVGVIQPGARTAIKVTKNQHIGVIGTVN
HHCCCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEEHH
TIKSRAYEQALLGLNAELQVENTACPLLVPFVESGRFLQESAEEAVEASLEPLKGTSIDT
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCHHE
LILGCTHYPILKDPIQNYMGEHVKIISSGDETAREVSTILSYKGLLNQSKHAPEHQFLTT
EEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
GERNGFAKIAEDWFGHEIGHVECISLQEPVRK
CCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWEMTDY
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLENHHIKMLVIACNTATAIALEDIQRKTDIPVVGVIQPGARTAIKVTKNQHIGVIGTVN
HHCCCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEEEEHH
TIKSRAYEQALLGLNAELQVENTACPLLVPFVESGRFLQESAEEAVEASLEPLKGTSIDT
HHHHHHHHHHHHCCCCEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCHHE
LILGCTHYPILKDPIQNYMGEHVKIISSGDETAREVSTILSYKGLLNQSKHAPEHQFLTT
EEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
GERNGFAKIAEDWFGHEIGHVECISLQEPVRK
CCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA