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The map label for this gene is pheA [H]

Identifier: 154686925

GI number: 154686925

Start: 2615791

End: 2616648

Strand: Reverse

Name: pheA [H]

Synonym: RBAM_024950

Alternate gene names: 154686925

Gene position: 2616648-2615791 (Counterclockwise)

Preceding gene: 154686926

Following gene: 154686922

Centisome position: 66.78

GC content: 47.44

Gene sequence:

>858_bases
ATGAAAGTCGGTTATTTAGGGCCAGAAGCCACATTTACACATCTAGCAGTCAGTTCCTGCTTTCAAAACAGCGTGACACA
AGCACCTTATCAAACAATACCGGCATGCATGGATGCGGCGGTTGCGGGAGAAGTTGATCTTGCATTTGTTCCTTTGGAAA
ACGCGCTGGAAGGCTCGGTTAACTTAACGATTGACTATTTGATTCATGAGCAGCCTCTTGCGATCGTGGGGGAAATGACG
CTGCCGATTCACCAGCATCTGCTCGTTCACCCTTCGAGAGAAAATGAGTGGAAAAAGCTTGAGAAAATTTATTCTCATTC
CCATGCGATTGCGCAATGCCACAAATTTCTTCACCGGCATTTTTCGTCCGTTCCTTATGAGTATGCGAAGTCAACAGGTG
CGGCTGCCAAGTATGTCAGTGAGCATTCGGACCTTCCGATCGGCGTGATTGCAAATGAAATGGCCGCCGCTACATACGGA
TTGAGCATCGTGAAGCGGGATATTCAGGATTATCAGGACAACCACACGAGATTTGTCATTCTTTCGCCTGAAAAAGACGT
CTCATTCGAAGTGAATGCGAAACTGTCTTCACGGCCGAAAACGACGATGATGGTAACGCTTCCCCAAGATGACCAATCAG
GTGCGCTGCACAGGGTGCTGTCCGCTTTTTCATGGAGAAACCTGAATTTATCAAAGATCGAATCGCGCCCGACAAAAACG
GGTCTCGGCAACTATTTCTTTATTATTGATATTGAACAGGCGATGGATCAGGTTCTCATTCCCGGTGCCGTTCAAGAGAT
GGAAGCCCTCGGCTGCCGGGTCAAGCTTCTGGGAACATATCAATCCTATTCGATATAA

Upstream 100 bases:

>100_bases
ATGGAAGAAAACATTCATACGTTAATGAATAAACTGAGAAAATTTGATTTTATAGAAAAAGTTGAGATCTTAGGGTCAGG
CGCGTAAGGAGAGAAGAGAC

Downstream 100 bases:

>100_bases
AAAAAGCCCTTCAGGGGGCTTTTTTTTTAATCTTTTATTAAAATACCCGCGTCGTCCAGCGCTTGGCAGGCTTGGTCAAT
CCGCTCTTTTGTCGGGGCGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKVGYLGPEATFTHLAVSSCFQNSVTQAPYQTIPACMDAAVAGEVDLAFVPLENALEGSVNLTIDYLIHEQPLAIVGEMT
LPIHQHLLVHPSRENEWKKLEKIYSHSHAIAQCHKFLHRHFSSVPYEYAKSTGAAAKYVSEHSDLPIGVIANEMAAATYG
LSIVKRDIQDYQDNHTRFVILSPEKDVSFEVNAKLSSRPKTTMMVTLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGNYFFIIDIEQAMDQVLIPGAVQEMEALGCRVKLLGTYQSYSI

Sequences:

>Translated_285_residues
MKVGYLGPEATFTHLAVSSCFQNSVTQAPYQTIPACMDAAVAGEVDLAFVPLENALEGSVNLTIDYLIHEQPLAIVGEMT
LPIHQHLLVHPSRENEWKKLEKIYSHSHAIAQCHKFLHRHFSSVPYEYAKSTGAAAKYVSEHSDLPIGVIANEMAAATYG
LSIVKRDIQDYQDNHTRFVILSPEKDVSFEVNAKLSSRPKTTMMVTLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGNYFFIIDIEQAMDQVLIPGAVQEMEALGCRVKLLGTYQSYSI
>Mature_285_residues
MKVGYLGPEATFTHLAVSSCFQNSVTQAPYQTIPACMDAAVAGEVDLAFVPLENALEGSVNLTIDYLIHEQPLAIVGEMT
LPIHQHLLVHPSRENEWKKLEKIYSHSHAIAQCHKFLHRHFSSVPYEYAKSTGAAAKYVSEHSDLPIGVIANEMAAATYG
LSIVKRDIQDYQDNHTRFVILSPEKDVSFEVNAKLSSRPKTTMMVTLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
GLGNYFFIIDIEQAMDQVLIPGAVQEMEALGCRVKLLGTYQSYSI

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=291, Percent_Identity=30.9278350515464, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31693; Mature: 31693

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGYLGPEATFTHLAVSSCFQNSVTQAPYQTIPACMDAAVAGEVDLAFVPLENALEGSV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCE
NLTIDYLIHEQPLAIVGEMTLPIHQHLLVHPSRENEWKKLEKIYSHSHAIAQCHKFLHRH
EEEEEEEEECCCCEEEECCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSVPYEYAKSTGAAAKYVSEHSDLPIGVIANEMAAATYGLSIVKRDIQDYQDNHTRFVI
HHCCCHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LSPEKDVSFEVNAKLSSRPKTTMMVTLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
ECCCCCCEEEEECEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
GLGNYFFIIDIEQAMDQVLIPGAVQEMEALGCRVKLLGTYQSYSI
CCCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCC
>Mature Secondary Structure
MKVGYLGPEATFTHLAVSSCFQNSVTQAPYQTIPACMDAAVAGEVDLAFVPLENALEGSV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCE
NLTIDYLIHEQPLAIVGEMTLPIHQHLLVHPSRENEWKKLEKIYSHSHAIAQCHKFLHRH
EEEEEEEEECCCCEEEECCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSVPYEYAKSTGAAAKYVSEHSDLPIGVIANEMAAATYGLSIVKRDIQDYQDNHTRFVI
HHCCCHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LSPEKDVSFEVNAKLSSRPKTTMMVTLPQDDQSGALHRVLSAFSWRNLNLSKIESRPTKT
ECCCCCCEEEEECEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCC
GLGNYFFIIDIEQAMDQVLIPGAVQEMEALGCRVKLLGTYQSYSI
CCCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]