Click here to switch to the map view.

The map label for this gene is nadA

Identifier: 154686920

GI number: 154686920

Start: 2610468

End: 2611571

Strand: Reverse

Name: nadA

Synonym: RBAM_024900

Alternate gene names: 154686920

Gene position: 2611571-2610468 (Counterclockwise)

Preceding gene: 154686921

Following gene: 154686919

Centisome position: 66.65

GC content: 48.73

Gene sequence:

>1104_bases
ATGTCTATTTTTGACGTGCTAACTGCATCAGCCGAAATGATGCCGAGCCATTATAAAGACATGAGCACTGGAGAAATGGA
AAAGCGGGTCGCCGCCATTAAACGGGCTTTCGGAAAGCGCCTGTTCATTCCGGGGCATCACTATCAAAAAGACGAAGTAA
TACAATTCGCCGATACGGCAGGTGACTCCCTGCAGCTTGCTCAAGTGGCAGAAAAAAATAAAGAGGCGGAATATATTGTG
TTTTGCGGCGTGCATTTTATGGCGGAAACCGCTGATATGCTGACTGATGATAACCAAACCGTCATTTTGCCCGACATGCG
CGCCGGATGCTCGATGGCTGATATGGCAGATATTCAGCAGACGGACAAAGCATGGCAAGAGCTTCAAGAACTGTACGGTA
ACACCATCATTCCGTTAACATATGTTAACTCGACGGCGGAAATTAAAGCATTCGTCGGACGGCACGGGGGAGCGACCGTC
ACCTCTTCGAATGCCCGGAGTGTGCTGAAATGGGCTTTTAAACAAAAAGAGAGAATTTTATTTTTGCCGGATCAGCATTT
AGGCAGAAATACGGCCTATGACCTCGGCATTCCGCTGACAGAAATGGCTGTATGGGACCCGGTGCAGAACCGATTGCTTA
CTGACCATCCGGAAAACATTAAGGTTATCCTTTGGAAAGGGCATTGCTCCGTACACGAAAAGTTTACAGCGGAAAATATT
TCTCAGCTGCGGCAGCGGGATTCCGGCATCCGCATTATCGTTCATCCGGAATGTTCGCGGGAAGTGGTCTCGCTCAGTGA
CGACAGCGGGTCTACCAAATACATTATTGATACGATCGAACAGGCTGAACCGGGAAGCAAGTGGGCGATCGGCACGGAAA
TGAATCTTGTCCAGCGCCTCATTCACTCGCATCCGGATAAACAGATTGAATCATTGAATCCCGATATGTGTCCGTGTCTG
ACAATGAACAGAATCGACCTGCCGCATTTATTGTGGTCGCTTGAGCAGCTTGAAAAAGGCGAGCCGAAGGGTGTCATTAA
AGTTCCGGAAGCGGTTCGGACAGAAGCGCTTCGTGCTTTGAACAGAATGCTGAGTCATACGTAA

Upstream 100 bases:

>100_bases
ACGGGGGTCCAATATATTTCACTCGGATTTCTGACTCATTCAGTAAAAAGCGCCGACATCAGCATGGATGTTGAGGCAGC
GGAACAGGGGGATTTTTAAG

Downstream 100 bases:

>100_bases
TTATAAAAATTTCCCCTCCTTCCCAAATTTTTTATCATCATGCCCAGTCCATCGGCATATAGTGTGAAGAAACGTATTGT
AATGACAAATGTACCGTTCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSIFDVLTASAEMMPSHYKDMSTGEMEKRVAAIKRAFGKRLFIPGHHYQKDEVIQFADTAGDSLQLAQVAEKNKEAEYIV
FCGVHFMAETADMLTDDNQTVILPDMRAGCSMADMADIQQTDKAWQELQELYGNTIIPLTYVNSTAEIKAFVGRHGGATV
TSSNARSVLKWAFKQKERILFLPDQHLGRNTAYDLGIPLTEMAVWDPVQNRLLTDHPENIKVILWKGHCSVHEKFTAENI
SQLRQRDSGIRIIVHPECSREVVSLSDDSGSTKYIIDTIEQAEPGSKWAIGTEMNLVQRLIHSHPDKQIESLNPDMCPCL
TMNRIDLPHLLWSLEQLEKGEPKGVIKVPEAVRTEALRALNRMLSHT

Sequences:

>Translated_367_residues
MSIFDVLTASAEMMPSHYKDMSTGEMEKRVAAIKRAFGKRLFIPGHHYQKDEVIQFADTAGDSLQLAQVAEKNKEAEYIV
FCGVHFMAETADMLTDDNQTVILPDMRAGCSMADMADIQQTDKAWQELQELYGNTIIPLTYVNSTAEIKAFVGRHGGATV
TSSNARSVLKWAFKQKERILFLPDQHLGRNTAYDLGIPLTEMAVWDPVQNRLLTDHPENIKVILWKGHCSVHEKFTAENI
SQLRQRDSGIRIIVHPECSREVVSLSDDSGSTKYIIDTIEQAEPGSKWAIGTEMNLVQRLIHSHPDKQIESLNPDMCPCL
TMNRIDLPHLLWSLEQLEKGEPKGVIKVPEAVRTEALRALNRMLSHT
>Mature_366_residues
SIFDVLTASAEMMPSHYKDMSTGEMEKRVAAIKRAFGKRLFIPGHHYQKDEVIQFADTAGDSLQLAQVAEKNKEAEYIVF
CGVHFMAETADMLTDDNQTVILPDMRAGCSMADMADIQQTDKAWQELQELYGNTIIPLTYVNSTAEIKAFVGRHGGATVT
SSNARSVLKWAFKQKERILFLPDQHLGRNTAYDLGIPLTEMAVWDPVQNRLLTDHPENIKVILWKGHCSVHEKFTAENIS
QLRQRDSGIRIIVHPECSREVVSLSDDSGSTKYIIDTIEQAEPGSKWAIGTEMNLVQRLIHSHPDKQIESLNPDMCPCLT
MNRIDLPHLLWSLEQLEKGEPKGVIKVPEAVRTEALRALNRMLSHT

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=26.5129682997118, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BACA2 (A7Z774)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422081.1
- ProteinModelPortal:   A7Z774
- SMR:   A7Z774
- STRING:   A7Z774
- EnsemblBacteria:   EBBACT00000007867
- GeneID:   5462460
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_024900
- eggNOG:   COG0379
- GeneTree:   EBGT00050000002444
- HOGENOM:   HBG291157
- OMA:   GTELNLV
- ProtClustDB:   PRK09375
- BioCyc:   BAMY326423:RBAM_024900-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41353; Mature: 41222

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: BINDING 46-46 BINDING 63-63 BINDING 141-141 BINDING 162-162 BINDING 255-255 BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFDVLTASAEMMPSHYKDMSTGEMEKRVAAIKRAFGKRLFIPGHHYQKDEVIQFADTA
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCC
GDSLQLAQVAEKNKEAEYIVFCGVHFMAETADMLTDDNQTVILPDMRAGCSMADMADIQQ
CCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TDKAWQELQELYGNTIIPLTYVNSTAEIKAFVGRHGGATVTSSNARSVLKWAFKQKERIL
HHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCEE
FLPDQHLGRNTAYDLGIPLTEMAVWDPVQNRLLTDHPENIKVILWKGHCSVHEKFTAENI
ECCCHHCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
SQLRQRDSGIRIIVHPECSREVVSLSDDSGSTKYIIDTIEQAEPGSKWAIGTEMNLVQRL
HHHHHCCCCCEEEECCCCCCCCEEECCCCCCCEEEEEEHHHCCCCCCEECCCHHHHHHHH
IHSHPDKQIESLNPDMCPCLTMNRIDLPHLLWSLEQLEKGEPKGVIKVPEAVRTEALRAL
HHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
NRMLSHT
HHHHHCC
>Mature Secondary Structure 
SIFDVLTASAEMMPSHYKDMSTGEMEKRVAAIKRAFGKRLFIPGHHYQKDEVIQFADTA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHCCC
GDSLQLAQVAEKNKEAEYIVFCGVHFMAETADMLTDDNQTVILPDMRAGCSMADMADIQQ
CCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
TDKAWQELQELYGNTIIPLTYVNSTAEIKAFVGRHGGATVTSSNARSVLKWAFKQKERIL
HHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCEE
FLPDQHLGRNTAYDLGIPLTEMAVWDPVQNRLLTDHPENIKVILWKGHCSVHEKFTAENI
ECCCHHCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
SQLRQRDSGIRIIVHPECSREVVSLSDDSGSTKYIIDTIEQAEPGSKWAIGTEMNLVQRL
HHHHHCCCCCEEEECCCCCCCCEEECCCCCCCEEEEEEHHHCCCCCCEECCCHHHHHHHH
IHSHPDKQIESLNPDMCPCLTMNRIDLPHLLWSLEQLEKGEPKGVIKVPEAVRTEALRAL
HHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
NRMLSHT
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA