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The map label for this gene is yrvO [H]

Identifier: 154686892

GI number: 154686892

Start: 2581199

End: 2582338

Strand: Reverse

Name: yrvO [H]

Synonym: RBAM_024620

Alternate gene names: 154686892

Gene position: 2582338-2581199 (Counterclockwise)

Preceding gene: 154686893

Following gene: 154686891

Centisome position: 65.9

GC content: 51.75

Gene sequence:

>1140_bases
ATGGAACGGATTTATTTAGATCATGCCGCGACTTCCCCGATGGATGAGCGTGTGCTCGAAGAGATGAAGCCCCATTTCTT
CGGCAGTTTCGGCAACCCGTCAAGCATTCATTCATTCGGGAGAGAATCCCGGAAATGGGTCGATGAAGCGAGAGCGGACA
TCGCGCGCGAAATCAGTGCGAAAGAACAGGAAATTATTTTCACAAGCGGCGGCACGGAGGCTGATAATTTAGCGATTTTC
GGAACGGCTGCCGCCCGGAAGAATGAAGGAAAGCATATCATTACGACCGCTATTGAGCATCATGCTGTATTGCACGCCTG
CGAAAAGCTGGAAGAAGACGGCTTTGAGGTGACATACCTCATCCCCGGCCCTTCAGGACGGATCAGTGCAAATCAGGTGA
AAGAAGCGCTCCGTGATGATACAATCCTTGTTACCGTCATGTATGGCAATAACGAAGTCGGTACCATTCAGCCGATTGAC
GAAATCGGAGAGCTGTTAAGCGGGCATCAGGCCTATTTTCACACAGATGCCGTCCAGGCATTCGGTTATATGCCGATTGA
CGTGAAAAAAAGCAGAATTGACATGCTGTCTGTTTCCGGTCACAAGCTTAACGGGCCTAAAGGGACAGGCTTTTTATATG
TAAATCAAGAGGTGAAGCTGTCACCGATTCTTCTCGGGGGAGAGCAGGAACGAAAGCGCCGCGCGGGGACGGAAAATGTA
CCGGGCATCGCCGGCTTAAAAGAAGCGGTCGTCCTTTCAAACCGTGAGAGGGAAGAGAAAACAGCGAAGTATAAGGAGTT
TAAGAACATCATCATGAGCACGCTGGAAAAATCCGGCGTCACAGCGGAGGTGAACGGAGATGCCGAGAAATGCCTGCCTC
ATATTTTAAACCTTTACTTTCCCGGTGTGCCGGTGGAAGCGCTGCTGGTCAATCTTGACATGGAAGGCGTTGCCGTCTCC
AGCGGATCTGCTTGTACAGCGGGATCCGTTCTTCCGTCCCATGTGCTTACGGCCATGTTCGGAAGTGAGAGCGGCAGGCT
GACTTCGTCAATCCGCCTCAGCTTCGGCCTCGGCAATACGGCGGAACAAATCGAAACAGCCGCCGAAAAGCTTGCCGCCG
TCGTTAAACGGCTTGCTTAA

Upstream 100 bases:

>100_bases
AGACGTGCTGGACAGCACGACGTTAGAAGACCTTGCGAGCTACACGGACGGCGAGCAGGAAGCTTATATGTTCTATATTT
AAACCAGAGGTGTACAGACA

Downstream 100 bases:

>100_bases
AACGGCGGACTTACGTTTTTAATGGAGTGAATGCAAATGGAAAAACGGCCGGAGGATACAAGAGTCGTAGTCGGCATGTC
CGGCGGCGTGGACTCTTCCG

Product: YrvO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MERIYLDHAATSPMDERVLEEMKPHFFGSFGNPSSIHSFGRESRKWVDEARADIAREISAKEQEIIFTSGGTEADNLAIF
GTAAARKNEGKHIITTAIEHHAVLHACEKLEEDGFEVTYLIPGPSGRISANQVKEALRDDTILVTVMYGNNEVGTIQPID
EIGELLSGHQAYFHTDAVQAFGYMPIDVKKSRIDMLSVSGHKLNGPKGTGFLYVNQEVKLSPILLGGEQERKRRAGTENV
PGIAGLKEAVVLSNREREEKTAKYKEFKNIIMSTLEKSGVTAEVNGDAEKCLPHILNLYFPGVPVEALLVNLDMEGVAVS
SGSACTAGSVLPSHVLTAMFGSESGRLTSSIRLSFGLGNTAEQIETAAEKLAAVVKRLA

Sequences:

>Translated_379_residues
MERIYLDHAATSPMDERVLEEMKPHFFGSFGNPSSIHSFGRESRKWVDEARADIAREISAKEQEIIFTSGGTEADNLAIF
GTAAARKNEGKHIITTAIEHHAVLHACEKLEEDGFEVTYLIPGPSGRISANQVKEALRDDTILVTVMYGNNEVGTIQPID
EIGELLSGHQAYFHTDAVQAFGYMPIDVKKSRIDMLSVSGHKLNGPKGTGFLYVNQEVKLSPILLGGEQERKRRAGTENV
PGIAGLKEAVVLSNREREEKTAKYKEFKNIIMSTLEKSGVTAEVNGDAEKCLPHILNLYFPGVPVEALLVNLDMEGVAVS
SGSACTAGSVLPSHVLTAMFGSESGRLTSSIRLSFGLGNTAEQIETAAEKLAAVVKRLA
>Mature_379_residues
MERIYLDHAATSPMDERVLEEMKPHFFGSFGNPSSIHSFGRESRKWVDEARADIAREISAKEQEIIFTSGGTEADNLAIF
GTAAARKNEGKHIITTAIEHHAVLHACEKLEEDGFEVTYLIPGPSGRISANQVKEALRDDTILVTVMYGNNEVGTIQPID
EIGELLSGHQAYFHTDAVQAFGYMPIDVKKSRIDMLSVSGHKLNGPKGTGFLYVNQEVKLSPILLGGEQERKRRAGTENV
PGIAGLKEAVVLSNREREEKTAKYKEFKNIIMSTLEKSGVTAEVNGDAEKCLPHILNLYFPGVPVEALLVNLDMEGVAVS
SGSACTAGSVLPSHVLTAMFGSESGRLTSSIRLSFGLGNTAEQIETAAEKLAAVVKRLA

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=378, Percent_Identity=42.3280423280423, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI156713448, Length=413, Percent_Identity=30.2663438256659, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI48994898, Length=380, Percent_Identity=43.1578947368421, Blast_Score=284, Evalue=7e-78,
Organism=Escherichia coli, GI1787970, Length=407, Percent_Identity=24.8157248157248, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789175, Length=393, Percent_Identity=26.4631043256997, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25143064, Length=366, Percent_Identity=43.4426229508197, Blast_Score=284, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17533177, Length=323, Percent_Identity=32.1981424148607, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319831, Length=378, Percent_Identity=42.8571428571429, Blast_Score=279, Evalue=6e-76,
Organism=Drosophila melanogaster, GI20129463, Length=378, Percent_Identity=43.1216931216931, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41138; Mature: 41138

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIYLDHAATSPMDERVLEEMKPHFFGSFGNPSSIHSFGRESRKWVDEARADIAREISA
CCEEEECCCCCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KEQEIIFTSGGTEADNLAIFGTAAARKNEGKHIITTAIEHHAVLHACEKLEEDGFEVTYL
CCCEEEEECCCCCCCCEEEEEEHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEE
IPGPSGRISANQVKEALRDDTILVTVMYGNNEVGTIQPIDEIGELLSGHQAYFHTDAVQA
ECCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEHHHHHH
FGYMPIDVKKSRIDMLSVSGHKLNGPKGTGFLYVNQEVKLSPILLGGEQERKRRAGTENV
HCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEEEEECCCHHHHHCCCCCCC
PGIAGLKEAVVLSNREREEKTAKYKEFKNIIMSTLEKSGVTAEVNGDAEKCLPHILNLYF
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHC
PGVPVEALLVNLDMEGVAVSSGSACTAGSVLPSHVLTAMFGSESGRLTSSIRLSFGLGNT
CCCCHHHEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCH
AEQIETAAEKLAAVVKRLA
HHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MERIYLDHAATSPMDERVLEEMKPHFFGSFGNPSSIHSFGRESRKWVDEARADIAREISA
CCEEEECCCCCCCHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KEQEIIFTSGGTEADNLAIFGTAAARKNEGKHIITTAIEHHAVLHACEKLEEDGFEVTYL
CCCEEEEECCCCCCCCEEEEEEHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEE
IPGPSGRISANQVKEALRDDTILVTVMYGNNEVGTIQPIDEIGELLSGHQAYFHTDAVQA
ECCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCHHEEEHHHHHH
FGYMPIDVKKSRIDMLSVSGHKLNGPKGTGFLYVNQEVKLSPILLGGEQERKRRAGTENV
HCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEEEEECCCHHHHHCCCCCCC
PGIAGLKEAVVLSNREREEKTAKYKEFKNIIMSTLEKSGVTAEVNGDAEKCLPHILNLYF
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHC
PGVPVEALLVNLDMEGVAVSSGSACTAGSVLPSHVLTAMFGSESGRLTSSIRLSFGLGNT
CCCCHHHEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCH
AEQIETAAEKLAAVVKRLA
HHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]