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The map label for this gene is yrrR [H]

Identifier: 154686871

GI number: 154686871

Start: 2560288

End: 2562042

Strand: Reverse

Name: yrrR [H]

Synonym: RBAM_024410

Alternate gene names: 154686871

Gene position: 2562042-2560288 (Counterclockwise)

Preceding gene: 154686872

Following gene: 154686870

Centisome position: 65.38

GC content: 46.84

Gene sequence:

>1755_bases
ATGATCGTATCAAAAAGGCTGAAAGCGGCCGTGATTTGTTTTCTGCTCGTGTTTTTCTTTCTGCTTGCGAGGCTGGCTGA
AATTCAGCTGTTTTTCACAGAATCTTTTTCAAAATCCAATATTAATCTGATTCAGGAAAGCGTCAAGCAGCGGACGGAAG
AAGTCCTTATTTCAGACGGACGCGGCTCTTTTCTTGATCGGAACGGCAAAGAACTGACCGGAAAAAAGCAGCCTGCCGTC
ATACTGTTTCCCTTTCTCGTGACGCAGGATTGGCCGGTTGACCGGGTATCTGACATTCTCGGAATGAAACAGGGGGAGCT
CAGGCAGCTGCTCACGGAAGCGAAAAAACCGGTGGTCCTGAACAGCAGAAAAATAAAACATTTGACGAAACAATCCGTGT
CAAATATCAATTCTTTGAAATATCCCGGCATTTACGGCGTATATATGAAAGACAGCAAGGAAACAAACATAGCCGCTCAT
CTGTTGGGCGCGACAAACCAGGACCCTGAGCTTTTGAAAAAGAAATACCCCGGCAGGAAGGAACTGCCGATCACGGCAAA
GATCGGGACAAGCGGGATGGAGCGGACGTTTGATGAGTTTTTACTGGCGGATCAGGACACAAAACTTTTGTATCATGTCG
ACGGAAGGGGAAACCCTTTATTCGGAATGGACGTCAAATATACGGCTGAAGCAAACGCGTTTTATCCGCTGCAAGTCAAA
ACCTCCATCGACCGCAATATTCAAAAAGCAATGGAAGATGTATTGAAAGACCGCGGGTTAAAAAAGGGGGGAGCCGTCCT
TTTAGACATTGAAAAAAGCAGTGTGCTCGGAATGGTATCAAAGCCTGACGCCGACATGTCAAAGCAGCAGACACTGCAAA
ATTACATGCTGACGCCGATTTATCCGGGATCAGTGTTTAAAACGGTGATCGCCGCAGCCGCAATAGAACAAAACGAAGTG
AAGCCGGGCACATCCTTTAACTGCAATCTCAACCTGTACGGAGAGCCGGGGGATGACAAAGGCACGCTCAGTTTTGGAGA
AAGCTTTGCCCAAAGCTGCAATTATACGTTTACAAGTCTTGCGGAAAAATTGATCAAAAAAGATGATTCCGTTATTGAAA
ACATGGCGGAAAAACTCGGTCTCACACAGCGGGCGGGCTGGGAAGGCAAGCTGTACCGGGAAGACGGATTCAGGCAGCTG
TATAATGAAAAAAGCGGGGTCATTTGGGGAGATGACAAAGACAAAACCGTAAAAAAAGCCGTCGCACAGACGGCGATCGG
GCAAAAAAACGTGAAAGTCACGCCTCTTGAAGTCGCCAATATGATGGCGGCGATCGCGCGCGGCGGTGAAAAAAAACAAG
TCAAAATCGCGGACAAAATTGAATACAAAAACAAAACGACGATGGCGTCATTCAAAGATCAGCCGTTAAAAGGGGAAAAC
ATCGACAAATATACGGCGCAGCAGCTTCAAAAAATTCTCAGAGAAGTCGTCACCTCACCGAAAGGAACCGGCCGAAGGTT
TCAGGATCTGCCGTATGAGATAGCAGGCAAATCGGGAACGGCCCAGACGGGAATGTTCACAAAAGATAAACAGACGCTTT
ACCACAAATGGTTTGCGGGATACTTTCCCGCGGACAAGCCGAAATACGCTCTCGTGGTGCTGCACATGGACACGCCGGGG
GATAAGGCTCTGACAAATACAGTGTTTTATGATATTGTTAAAAAGGTACATGAAAATGAAATAAATCAGACATAG

Upstream 100 bases:

>100_bases
AGACGCCGGGCGGAGAAATGCTCGTGAAAATTGTGAAAATTTCATAAGATCCGTTTAACAATGAAACACCTCGTCCAAAA
TGTGGATGAGGTGTTTTTTT

Downstream 100 bases:

>100_bases
AACAACCGCTCAGCCCATGTTAAAATATATGCTGAGCAAGAGGGATAAAGGAGTGCAGAATGATTGAGCAATAAACAATC
TCGTTTTGAAAACCGTGATA

Product: YrrR

Products: NA

Alternate protein names: PBP-4B; PBP4b; Penicillin-binding protein I [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MIVSKRLKAAVICFLLVFFFLLARLAEIQLFFTESFSKSNINLIQESVKQRTEEVLISDGRGSFLDRNGKELTGKKQPAV
ILFPFLVTQDWPVDRVSDILGMKQGELRQLLTEAKKPVVLNSRKIKHLTKQSVSNINSLKYPGIYGVYMKDSKETNIAAH
LLGATNQDPELLKKKYPGRKELPITAKIGTSGMERTFDEFLLADQDTKLLYHVDGRGNPLFGMDVKYTAEANAFYPLQVK
TSIDRNIQKAMEDVLKDRGLKKGGAVLLDIEKSSVLGMVSKPDADMSKQQTLQNYMLTPIYPGSVFKTVIAAAAIEQNEV
KPGTSFNCNLNLYGEPGDDKGTLSFGESFAQSCNYTFTSLAEKLIKKDDSVIENMAEKLGLTQRAGWEGKLYREDGFRQL
YNEKSGVIWGDDKDKTVKKAVAQTAIGQKNVKVTPLEVANMMAAIARGGEKKQVKIADKIEYKNKTTMASFKDQPLKGEN
IDKYTAQQLQKILREVVTSPKGTGRRFQDLPYEIAGKSGTAQTGMFTKDKQTLYHKWFAGYFPADKPKYALVVLHMDTPG
DKALTNTVFYDIVKKVHENEINQT

Sequences:

>Translated_584_residues
MIVSKRLKAAVICFLLVFFFLLARLAEIQLFFTESFSKSNINLIQESVKQRTEEVLISDGRGSFLDRNGKELTGKKQPAV
ILFPFLVTQDWPVDRVSDILGMKQGELRQLLTEAKKPVVLNSRKIKHLTKQSVSNINSLKYPGIYGVYMKDSKETNIAAH
LLGATNQDPELLKKKYPGRKELPITAKIGTSGMERTFDEFLLADQDTKLLYHVDGRGNPLFGMDVKYTAEANAFYPLQVK
TSIDRNIQKAMEDVLKDRGLKKGGAVLLDIEKSSVLGMVSKPDADMSKQQTLQNYMLTPIYPGSVFKTVIAAAAIEQNEV
KPGTSFNCNLNLYGEPGDDKGTLSFGESFAQSCNYTFTSLAEKLIKKDDSVIENMAEKLGLTQRAGWEGKLYREDGFRQL
YNEKSGVIWGDDKDKTVKKAVAQTAIGQKNVKVTPLEVANMMAAIARGGEKKQVKIADKIEYKNKTTMASFKDQPLKGEN
IDKYTAQQLQKILREVVTSPKGTGRRFQDLPYEIAGKSGTAQTGMFTKDKQTLYHKWFAGYFPADKPKYALVVLHMDTPG
DKALTNTVFYDIVKKVHENEINQT
>Mature_584_residues
MIVSKRLKAAVICFLLVFFFLLARLAEIQLFFTESFSKSNINLIQESVKQRTEEVLISDGRGSFLDRNGKELTGKKQPAV
ILFPFLVTQDWPVDRVSDILGMKQGELRQLLTEAKKPVVLNSRKIKHLTKQSVSNINSLKYPGIYGVYMKDSKETNIAAH
LLGATNQDPELLKKKYPGRKELPITAKIGTSGMERTFDEFLLADQDTKLLYHVDGRGNPLFGMDVKYTAEANAFYPLQVK
TSIDRNIQKAMEDVLKDRGLKKGGAVLLDIEKSSVLGMVSKPDADMSKQQTLQNYMLTPIYPGSVFKTVIAAAAIEQNEV
KPGTSFNCNLNLYGEPGDDKGTLSFGESFAQSCNYTFTSLAEKLIKKDDSVIENMAEKLGLTQRAGWEGKLYREDGFRQL
YNEKSGVIWGDDKDKTVKKAVAQTAIGQKNVKVTPLEVANMMAAIARGGEKKQVKIADKIEYKNKTTMASFKDQPLKGEN
IDKYTAQQLQKILREVVTSPKGTGRRFQDLPYEIAGKSGTAQTGMFTKDKQTLYHKWFAGYFPADKPKYALVVLHMDTPG
DKALTNTVFYDIVKKVHENEINQT

Specific function: Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these p

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65392; Mature: 65392

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVSKRLKAAVICFLLVFFFLLARLAEIQLFFTESFSKSNINLIQESVKQRTEEVLISDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHEEECC
RGSFLDRNGKELTGKKQPAVILFPFLVTQDWPVDRVSDILGMKQGELRQLLTEAKKPVVL
CCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEE
NSRKIKHLTKQSVSNINSLKYPGIYGVYMKDSKETNIAAHLLGATNQDPELLKKKYPGRK
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHEECCCCCCHHHHHHCCCCCC
ELPITAKIGTSGMERTFDEFLLADQDTKLLYHVDGRGNPLFGMDVKYTAEANAFYPLQVK
CCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCEEEEECCCCEEEEEEE
TSIDRNIQKAMEDVLKDRGLKKGGAVLLDIEKSSVLGMVSKPDADMSKQQTLQNYMLTPI
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHCCCCCC
YPGSVFKTVIAAAAIEQNEVKPGTSFNCNLNLYGEPGDDKGTLSFGESFAQSCNYTFTSL
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHH
AEKLIKKDDSVIENMAEKLGLTQRAGWEGKLYREDGFRQLYNEKSGVIWGDDKDKTVKKA
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHH
VAQTAIGQKNVKVTPLEVANMMAAIARGGEKKQVKIADKIEYKNKTTMASFKDQPLKGEN
HHHHHCCCCCCEECHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCHHCCCCCCCCCC
IDKYTAQQLQKILREVVTSPKGTGRRFQDLPYEIAGKSGTAQTGMFTKDKQTLYHKWFAG
CHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHC
YFPADKPKYALVVLHMDTPGDKALTNTVFYDIVKKVHENEINQT
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIVSKRLKAAVICFLLVFFFLLARLAEIQLFFTESFSKSNINLIQESVKQRTEEVLISDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHEEECC
RGSFLDRNGKELTGKKQPAVILFPFLVTQDWPVDRVSDILGMKQGELRQLLTEAKKPVVL
CCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEE
NSRKIKHLTKQSVSNINSLKYPGIYGVYMKDSKETNIAAHLLGATNQDPELLKKKYPGRK
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHEECCCCCCHHHHHHCCCCCC
ELPITAKIGTSGMERTFDEFLLADQDTKLLYHVDGRGNPLFGMDVKYTAEANAFYPLQVK
CCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCEEEEECCCCEEEEEEE
TSIDRNIQKAMEDVLKDRGLKKGGAVLLDIEKSSVLGMVSKPDADMSKQQTLQNYMLTPI
CHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHCCCCCC
YPGSVFKTVIAAAAIEQNEVKPGTSFNCNLNLYGEPGDDKGTLSFGESFAQSCNYTFTSL
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHH
AEKLIKKDDSVIENMAEKLGLTQRAGWEGKLYREDGFRQLYNEKSGVIWGDDKDKTVKKA
HHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHH
VAQTAIGQKNVKVTPLEVANMMAAIARGGEKKQVKIADKIEYKNKTTMASFKDQPLKGEN
HHHHHCCCCCCEECHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCHHCCCCCCCCCC
IDKYTAQQLQKILREVVTSPKGTGRRFQDLPYEIAGKSGTAQTGMFTKDKQTLYHKWFAG
CHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHC
YFPADKPKYALVVLHMDTPGDKALTNTVFYDIVKKVHENEINQT
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]