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The map label for this gene is comEA [H]

Identifier: 154686819

GI number: 154686819

Start: 2510020

End: 2510634

Strand: Reverse

Name: comEA [H]

Synonym: RBAM_023890

Alternate gene names: 154686819

Gene position: 2510634-2510020 (Counterclockwise)

Preceding gene: 154686821

Following gene: 154686818

Centisome position: 64.07

GC content: 49.92

Gene sequence:

>615_bases
ATGACGAAAGCGATGATGACGGAGCGGCTGCGGCGGAACCTGAAAATTCTGGGCGCTTGTCTTGCGGCAGGGGCGGTTTT
TATCTGTATTTGGCTGTTTCGTTCTGAAAAGGAAGAGCCGGTCAAACAGCAGTCCGTGCTCGGCCAAACAGCCTCAGCAT
CCGTCGCGGACAAAAAAGACACCGCAGCCGATAAGATTATGATTGATGTGAAAGGCGCGGTCCGAAATCCCGGCGTGTAT
GAAATGAAAGCGGGAGACAGGGTGACGCAAGCCATTGAAAAAGCCGGCGGCCTGAAGAAAAAGGCGGATGAATTGAATGT
TAATTTAGCAGAGCAGCTGCAGGACGGGACGATTGTTTATATTCCGAGTGAAGGCGAAGAGGAGAATCGCCCGAAAACAG
CGGCGGGTGAAAAGGAGAATGCAGCTGTCAATATCAATATGGCATCTCTGGACGAACTTCAGGCGATTTCCGGGGTGGGG
CAGAAAAAAGCGGAAGCGATTATCGCCTACCGAGAAGAAAACGGACGGTTTCAGACTGCTGAAGATTTGATGAATGTATC
AGGCTTTGGAGAAAAGTCATTTGAGCGGATAAAAACTTCCATTACGGTAAAGTGA

Upstream 100 bases:

>100_bases
GATCGTCCCCATGTTTCCGGTGCCGATAAAGCCTATTTTCAATGAATTCCCCTCCTTTTTCCCTTAATCCTCTAAACCTT
ATGCGGGGAGGCAATGCAAT

Downstream 100 bases:

>100_bases
ATTGACGGTTCTGCTTAAATCTATGTAAACTTAGAAAAGCAACAAGACTTTTTGGAGGGAACACTTGTGGAACGAATCTC
ATGGAATCAATATTTTATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTKAMMTERLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKDTAADKIMIDVKGAVRNPGVY
EMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVYIPSEGEEENRPKTAAGEKENAAVNINMASLDELQAISGVG
QKKAEAIIAYREENGRFQTAEDLMNVSGFGEKSFERIKTSITVK

Sequences:

>Translated_204_residues
MTKAMMTERLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKDTAADKIMIDVKGAVRNPGVY
EMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVYIPSEGEEENRPKTAAGEKENAAVNINMASLDELQAISGVG
QKKAEAIIAYREENGRFQTAEDLMNVSGFGEKSFERIKTSITVK
>Mature_203_residues
TKAMMTERLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKDTAADKIMIDVKGAVRNPGVYE
MKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVYIPSEGEEENRPKTAAGEKENAAVNINMASLDELQAISGVGQ
KKAEAIIAYREENGRFQTAEDLMNVSGFGEKSFERIKTSITVK

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

Organism=Escherichia coli, GI1786646, Length=63, Percent_Identity=52.3809523809524, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 22196; Mature: 22064

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAMMTERLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
TAADKIMIDVKGAVRNPGVYEMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVY
CCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHCCCEEEE
IPSEGEEENRPKTAAGEKENAAVNINMASLDELQAISGVGQKKAEAIIAYREENGRFQTA
ECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHEEEEEECCCCCEECH
EDLMNVSGFGEKSFERIKTSITVK
HHHHHHCCCCHHHHHHHHHHEECC
>Mature Secondary Structure 
TKAMMTERLRRNLKILGACLAAGAVFICIWLFRSEKEEPVKQQSVLGQTASASVADKKD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
TAADKIMIDVKGAVRNPGVYEMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVY
CCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHCCCEEEE
IPSEGEEENRPKTAAGEKENAAVNINMASLDELQAISGVGQKKAEAIIAYREENGRFQTA
ECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHEEEEEECCCCCEECH
EDLMNVSGFGEKSFERIKTSITVK
HHHHHHCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]