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The map label for this gene is comEB [H]

Identifier: 154686818

GI number: 154686818

Start: 2509384

End: 2509953

Strand: Reverse

Name: comEB [H]

Synonym: RBAM_023880

Alternate gene names: 154686818

Gene position: 2509953-2509384 (Counterclockwise)

Preceding gene: 154686819

Following gene: 154686817

Centisome position: 64.05

GC content: 45.09

Gene sequence:

>570_bases
GTGGAACGAATCTCATGGAATCAATATTTTATGGCGCAAAGCCATTTGCTGGCGCTGAGAAGCACATGTCCGAGACTGTC
AGTCGGGGCAACCGTAGTCAGAGATAAGCGGATGATTGCCGGCGGATACAACGGCTCAATTGCCGGCGGCGTCCATTGCG
CTGATGAAGGATGCCTTTTAATAGATAATCATTGCCAGAGGACCATACATGCAGAGATGAATGCGATTCTGCAATGTTCT
AAGTTCGGTGTTCCGACGGAGGGTGCCGAAATTTATGTGACGCATTATCCTTGTATTCAATGCTGCAAATCAATTATCCA
GGCAGGCATCAAAACGGTTTATTATGCTGAAGATTACAAAACACAGCCTTATGCAAAAGAGCTGTTCAGCCAAGCCGGAG
TCAAGGTGGAGCAGGTCGAACTTGATGAAATGATCATCGATCTGAAAAACCGCGAAAAATTGTCTTTTGTAGCAGGTCTG
ATTCAGCAATTATCTGATGCGGGGGTTAAGGCAGATGAACTGAAAAAAATTCATGAACAGGCCAATGAGCTGTTTACCAG
TTACGTATAA

Upstream 100 bases:

>100_bases
TGAGCGGATAAAAACTTCCATTACGGTAAAGTGAATTGACGGTTCTGCTTAAATCTATGTAAACTTAGAAAAGCAACAAG
ACTTTTTGGAGGGAACACTT

Downstream 100 bases:

>100_bases
ATGAAATATAAATACCTTCTTCTGCCTCTGGCGGCGGTTTCTGCAACTGCGGGAATTGCCGCCGCTCATGTCTTCTGGGT
TCTGCTCCTTTTTCTTCTGT

Product: hypothetical protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MERISWNQYFMAQSHLLALRSTCPRLSVGATVVRDKRMIAGGYNGSIAGGVHCADEGCLLIDNHCQRTIHAEMNAILQCS
KFGVPTEGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYKTQPYAKELFSQAGVKVEQVELDEMIIDLKNREKLSFVAGL
IQQLSDAGVKADELKKIHEQANELFTSYV

Sequences:

>Translated_189_residues
MERISWNQYFMAQSHLLALRSTCPRLSVGATVVRDKRMIAGGYNGSIAGGVHCADEGCLLIDNHCQRTIHAEMNAILQCS
KFGVPTEGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYKTQPYAKELFSQAGVKVEQVELDEMIIDLKNREKLSFVAGL
IQQLSDAGVKADELKKIHEQANELFTSYV
>Mature_189_residues
MERISWNQYFMAQSHLLALRSTCPRLSVGATVVRDKRMIAGGYNGSIAGGVHCADEGCLLIDNHCQRTIHAEMNAILQCS
KFGVPTEGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYKTQPYAKELFSQAGVKVEQVELDEMIIDLKNREKLSFVAGL
IQQLSDAGVKADELKKIHEQANELFTSYV

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=159, Percent_Identity=34.5911949685535, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI61742821, Length=159, Percent_Identity=34.5911949685535, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321938, Length=149, Percent_Identity=33.5570469798658, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667298, Length=154, Percent_Identity=35.0649350649351, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667302, Length=154, Percent_Identity=35.0649350649351, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 21083; Mature: 21083

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERISWNQYFMAQSHLLALRSTCPRLSVGATVVRDKRMIAGGYNGSIAGGVHCADEGCLL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEECCCCCCCCCCEEECCCCEEE
IDNHCQRTIHAEMNAILQCSKFGVPTEGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEECCCC
TQPYAKELFSQAGVKVEQVELDEMIIDLKNREKLSFVAGLIQQLSDAGVKADELKKIHEQ
CCHHHHHHHHHHCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ANELFTSYV
HHHHHHHCC
>Mature Secondary Structure
MERISWNQYFMAQSHLLALRSTCPRLSVGATVVRDKRMIAGGYNGSIAGGVHCADEGCLL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEECCCCCCCCCCEEECCCCEEE
IDNHCQRTIHAEMNAILQCSKFGVPTEGAEIYVTHYPCIQCCKSIIQAGIKTVYYAEDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHEEEEECCCC
TQPYAKELFSQAGVKVEQVELDEMIIDLKNREKLSFVAGLIQQLSDAGVKADELKKIHEQ
CCHHHHHHHHHHCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ANELFTSYV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]