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The map label for this gene is era [H]

Identifier: 154686789

GI number: 154686789

Start: 2479549

End: 2480454

Strand: Reverse

Name: era [H]

Synonym: RBAM_023590

Alternate gene names: 154686789

Gene position: 2480454-2479549 (Counterclockwise)

Preceding gene: 154686790

Following gene: 154686788

Centisome position: 63.3

GC content: 47.46

Gene sequence:

>906_bases
ATGACGAACGAAAGCTTTAAATCAGGATTTGTATCTATCATCGGAAGGCCGAATGTAGGAAAGTCTACCTTTTTAAACAG
GGTCATCGGTCAAAAGATCGCCATCATGAGCGACAAACCCCAGACGACAAGAAATAAAGTCCAAGGGGTGCTGACAACCG
GCACGTCGCAGACCATTTTTATTGATACACCGGGCATTCACAAACCAAAGCACAAGCTTGGCGACTTTATGATGAAAGTG
GCGCAGAATACGCTGAAAGAAGTTGACTTGGTGTTATTTATGATTAACGCCGAAGAAGGGTACGGAAAAGGCGACGAGTT
TATCATTGAAAAGCTCGGACAGACGTCTACACCGGTCTTTCTGATCGTTAACAAAATTGATAAGATCCATCCTGACCAGC
TGCTTCTTTTAATTGATGAGTACCGTACGCGCTATCCGTTTAAGGAAATCGTGCCGATCTCAGCTTTGGAAGGGAACAAC
GTCGAAACCCTTCTCGCGCAGATTGAAGCGTATTTACCGGAAGGGCCTCAGTTCTATCCGAGCGATCAGGTGACTGACCA
TCCCGAGCGGTTCATTATTTCTGAACTGATCAGGGAAAAGGTGCTCCATCTGACAAGGGAAGAAGTGCCGCACAGCATCG
CTGTCGCTATCGAGTCCATTAAAGGGCAGGAAAACGGCTCCGTCCATGTCGCCGCCACCATTGTGGTCGAGCGGGATTCT
CAAAAAGGCATCGTCATCGGCAAAAAAGGAGCGCTTCTGAAAGAAGTCGGCAAAAGAGCGCGGGCTGATATTGAAGCTCT
TTTGGGCTCACGCGTTTACCTGGAATTATGGGTGAAGGTGCAGAAGGACTGGCGGAATAAAATGTCTCAGCTGCGTGATT
TCGGCTTCAAAGAGGATGAATATTAA

Upstream 100 bases:

>100_bases
TCAAAGGATATGCTTGTTATTCTGACCAACTTACAAGGACAAATAAAAGAAATGACTGCGGAAGAATTATTACCAGGCGC
ATTTTCATCGGAGGATTTAC

Downstream 100 bases:

>100_bases
TTCATCTAAGGCGCATGCCTGAGGTGTGAGATTACCTCACAGAAGCAGGGATTCGTTAGCAAAATTTGTTTAACATGAAA
AGGAGGACATCAGGTCAAGA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: Bex protein [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIFIDTPGIHKPKHKLGDFMMKV
AQNTLKEVDLVLFMINAEEGYGKGDEFIIEKLGQTSTPVFLIVNKIDKIHPDQLLLLIDEYRTRYPFKEIVPISALEGNN
VETLLAQIEAYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEVPHSIAVAIESIKGQENGSVHVAATIVVERDS
QKGIVIGKKGALLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDEY

Sequences:

>Translated_301_residues
MTNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIFIDTPGIHKPKHKLGDFMMKV
AQNTLKEVDLVLFMINAEEGYGKGDEFIIEKLGQTSTPVFLIVNKIDKIHPDQLLLLIDEYRTRYPFKEIVPISALEGNN
VETLLAQIEAYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEVPHSIAVAIESIKGQENGSVHVAATIVVERDS
QKGIVIGKKGALLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDEY
>Mature_300_residues
TNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIFIDTPGIHKPKHKLGDFMMKVA
QNTLKEVDLVLFMINAEEGYGKGDEFIIEKLGQTSTPVFLIVNKIDKIHPDQLLLLIDEYRTRYPFKEIVPISALEGNNV
ETLLAQIEAYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEVPHSIAVAIESIKGQENGSVHVAATIVVERDSQ
KGIVIGKKGALLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDEY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. Binds both GDP and GTP. Complements

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=25.1552795031056, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=40.531561461794, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082120, Length=179, Percent_Identity=34.6368715083799, Blast_Score=98, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323665, Length=227, Percent_Identity=23.7885462555066, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646434, Length=313, Percent_Identity=25.5591054313099, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33930; Mature: 33798

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIF
CCCCCHHCCCEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHHHHCEEEEECCCCEEE
IDTPGIHKPKHKLGDFMMKVAQNTLKEVDLVLFMINAEEGYGKGDEFIIEKLGQTSTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHCCCCCCCEE
LIVNKIDKIHPDQLLLLIDEYRTRYPFKEIVPISALEGNNVETLLAQIEAYLPEGPQFYP
EEEEHHCCCCCCCEEEEEHHHHHHCCHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCC
SDQVTDHPERFIISELIREKVLHLTREEVPHSIAVAIESIKGQENGSVHVAATIVVERDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEEEECC
QKGIVIGKKGALLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDE
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C
>Mature Secondary Structure 
TNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIF
CCCCHHCCCEEEECCCCCCHHHHHHHHHHCEEEEECCCCCHHHHHHCEEEEECCCCEEE
IDTPGIHKPKHKLGDFMMKVAQNTLKEVDLVLFMINAEEGYGKGDEFIIEKLGQTSTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHCCCCCCCEE
LIVNKIDKIHPDQLLLLIDEYRTRYPFKEIVPISALEGNNVETLLAQIEAYLPEGPQFYP
EEEEHHCCCCCCCEEEEEHHHHHHCCHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCC
SDQVTDHPERFIISELIREKVLHLTREEVPHSIAVAIESIKGQENGSVHVAATIVVERDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEEEECC
QKGIVIGKKGALLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDE
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2526291 [H]