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The map label for this gene is glcK [H]

Identifier: 154686747

GI number: 154686747

Start: 2441498

End: 2442460

Strand: Reverse

Name: glcK [H]

Synonym: RBAM_023170

Alternate gene names: 154686747

Gene position: 2442460-2441498 (Counterclockwise)

Preceding gene: 154686748

Following gene: 154686746

Centisome position: 62.33

GC content: 52.34

Gene sequence:

>963_bases
ATGGAAGATACATGGTTTGCGGGGATTGATCTTGGCGGAACAACCATCAAGCTGGCCTTTATCAACATGTACGGTGAAAT
TCAGCATAAATGGGAAGTTCCGACCGATAAATCAGGAAACACAATTACGGTCACGATCGCCAAAGCGCTTGACCAGAAGC
TGGAAGAACTGAACAAGCCGAAACGGATCGTAAAATGGATCGGAATGGGAGCGCCCGGACCCGTGGAAATGGCGACGGGG
ATGGTCTATGAGACGACAAATATGGGGTGGAAAAACTATCCGCTGAAAGACCATCTCGAGGCGGAAACGGGTATTTCGGC
CGTCATTGAAAACGATGCCAATATCGCGGCGCTCGGAGAAATGTGGAAGGGTGCAGGTGACGGGGCCAAAGATGTCATTT
TAGTGACGCTCGGAACCGGAGTCGGCGGAGGCATCATCGTCAACGGAGAAATCGTTCACGGTAAAAACGGGGCCGGCGGA
GAAATCGGTCATATTTGCAGTATTCCGGAAGGAGGAGCTCCGTGCAACTGCGGAAAATCCGGCTGCATCGAAACGATTGC
GTCCGCAACAGGCATCGTCCGCATCGCGAAAGAAAAGCTTGCGGCTGTTTCCGACTCTTCGCTCTTACAAGTGCGCGATC
TGACGGCACGTGACGTGTTCGAAGCGGCTAAACAGCAGGATAAGACAGCGCTTGAAGTCGTCGATTATGTCGCAAAACAT
TTAGGCCTCGTGCTCGGAAATCTGGCAAGCGCCATGAATCCGACGAAAATCGTGCTCGGCGGAGGCGTGTCTAAAGCGGG
TGAAATCCTGCGGTCAAAAGTTGAAGAGACTTTCAAAATCACCGCGTTCCCGCGTTCTGCGGAAGCAGCGGATATTTCGA
TTGCGGCACTTGGAAATGACGCCGGAGTCATCGGCGGGGCGTGGATTGCCAAAAATGAATGGCTCAAACATCAAAACTGC
TGA

Upstream 100 bases:

>100_bases
AGAGAATTATGGCAAAAAGCCGCCGGAGTTCTTCAGAGAGAATCGGAGCGGATCAAAGGCAGATAACAAAGCAGGATTTT
AATAAGAAAAGGAGATTATT

Downstream 100 bases:

>100_bases
AGAAAGTCTGCCTGCCCATATCGCGGGCGGCTTTCTTTTTTTATCTCCCCAGTCATATAGTTTTTAAAAAAGGGGGATGA
ACATGGCGGGAATTCGTGTC

Product: GlcK

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MEDTWFAGIDLGGTTIKLAFINMYGEIQHKWEVPTDKSGNTITVTIAKALDQKLEELNKPKRIVKWIGMGAPGPVEMATG
MVYETTNMGWKNYPLKDHLEAETGISAVIENDANIAALGEMWKGAGDGAKDVILVTLGTGVGGGIIVNGEIVHGKNGAGG
EIGHICSIPEGGAPCNCGKSGCIETIASATGIVRIAKEKLAAVSDSSLLQVRDLTARDVFEAAKQQDKTALEVVDYVAKH
LGLVLGNLASAMNPTKIVLGGGVSKAGEILRSKVEETFKITAFPRSAEAADISIAALGNDAGVIGGAWIAKNEWLKHQNC

Sequences:

>Translated_320_residues
MEDTWFAGIDLGGTTIKLAFINMYGEIQHKWEVPTDKSGNTITVTIAKALDQKLEELNKPKRIVKWIGMGAPGPVEMATG
MVYETTNMGWKNYPLKDHLEAETGISAVIENDANIAALGEMWKGAGDGAKDVILVTLGTGVGGGIIVNGEIVHGKNGAGG
EIGHICSIPEGGAPCNCGKSGCIETIASATGIVRIAKEKLAAVSDSSLLQVRDLTARDVFEAAKQQDKTALEVVDYVAKH
LGLVLGNLASAMNPTKIVLGGGVSKAGEILRSKVEETFKITAFPRSAEAADISIAALGNDAGVIGGAWIAKNEWLKHQNC
>Mature_320_residues
MEDTWFAGIDLGGTTIKLAFINMYGEIQHKWEVPTDKSGNTITVTIAKALDQKLEELNKPKRIVKWIGMGAPGPVEMATG
MVYETTNMGWKNYPLKDHLEAETGISAVIENDANIAALGEMWKGAGDGAKDVILVTLGTGVGGGIIVNGEIVHGKNGAGG
EIGHICSIPEGGAPCNCGKSGCIETIASATGIVRIAKEKLAAVSDSSLLQVRDLTARDVFEAAKQQDKTALEVVDYVAKH
LGLVLGNLASAMNPTKIVLGGGVSKAGEILRSKVEETFKITAFPRSAEAADISIAALGNDAGVIGGAWIAKNEWLKHQNC

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI298566325, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI190014632, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4885285, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1787878, Length=268, Percent_Identity=30.9701492537313, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786891, Length=277, Percent_Identity=28.8808664259928, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081733, Length=317, Percent_Identity=31.2302839116719, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787363, Length=314, Percent_Identity=27.0700636942675, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082127, Length=244, Percent_Identity=26.6393442622951, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=29.6153846153846, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790522, Length=319, Percent_Identity=24.4514106583072, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33578; Mature: 33578

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDTWFAGIDLGGTTIKLAFINMYGEIQHKWEVPTDKSGNTITVTIAKALDQKLEELNKP
CCCCEEEEEECCCCEEEEEEEEEECCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCH
KRIVKWIGMGAPGPVEMATGMVYETTNMGWKNYPLKDHLEAETGISAVIENDANIAALGE
HHHHHHHCCCCCCCHHHHCCEEEEECCCCCCCCCCHHHCCHHCCCEEEEECCCCEEEHHH
MWKGAGDGAKDVILVTLGTGVGGGIIVNGEIVHGKNGAGGEIGHICSIPEGGAPCNCGKS
HHCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCH
GCIETIASATGIVRIAKEKLAAVSDSSLLQVRDLTARDVFEAAKQQDKTALEVVDYVAKH
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHH
LGLVLGNLASAMNPTKIVLGGGVSKAGEILRSKVEETFKITAFPRSAEAADISIAALGND
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCC
AGVIGGAWIAKNEWLKHQNC
CCEECCEEEECCCCCCCCCC
>Mature Secondary Structure
MEDTWFAGIDLGGTTIKLAFINMYGEIQHKWEVPTDKSGNTITVTIAKALDQKLEELNKP
CCCCEEEEEECCCCEEEEEEEEEECCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCH
KRIVKWIGMGAPGPVEMATGMVYETTNMGWKNYPLKDHLEAETGISAVIENDANIAALGE
HHHHHHHCCCCCCCHHHHCCEEEEECCCCCCCCCCHHHCCHHCCCEEEEECCCCEEEHHH
MWKGAGDGAKDVILVTLGTGVGGGIIVNGEIVHGKNGAGGEIGHICSIPEGGAPCNCGKS
HHCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCH
GCIETIASATGIVRIAKEKLAAVSDSSLLQVRDLTARDVFEAAKQQDKTALEVVDYVAKH
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHH
LGLVLGNLASAMNPTKIVLGGGVSKAGEILRSKVEETFKITAFPRSAEAADISIAALGND
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCC
AGVIGGAWIAKNEWLKHQNC
CCEECCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9620975 [H]