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The map label for this gene is yqjD [H]

Identifier: 154686653

GI number: 154686653

Start: 2359462

End: 2360985

Strand: Reverse

Name: yqjD [H]

Synonym: RBAM_022220

Alternate gene names: 154686653

Gene position: 2360985-2359462 (Counterclockwise)

Preceding gene: 154686654

Following gene: 154686652

Centisome position: 60.25

GC content: 50.07

Gene sequence:

>1524_bases
ATGAGCATGAGTGATCATATCAGACACTTAAACGAAAGACGTTCCTTTTTAACAAACGGCGGCGGAGCGGAAAAAAATGA
AAAACAGCACAAAAAAGGCAAGCTGACGGCAAGAGAAAGAATTGACTATTTATTGGACGAAGACAGTTTTTCAGAGCTGC
AGCCGTTTGCCAAAAGCTGCATGCCCGGATGCCAGAATGCTCCGGGAGACGGCGTTGTTACCGGATACGGCACAATTGAC
GGACGGCCCGTGTATTTGTTTGCCCATGACTTTACCGTACTCGGCGGGACGCTCGGCGAGACACATGCGGAAAAAATCGC
GGCGGTAATGGATCTGGCGGCGAAAAATAAAACTCCGATCATCGGGCTGAACGACTCAGGTGGTGCGAGAATTCAAGAGG
GTGTGGTATCATTAAATGGATACGGTCATATCTTTAGGCGCAACGTCCTTTACTCGGGAGTGATTCCGCAAATCTCTGTC
ATCCTTGGGCCGTGTGCCGGCGGTGCTGTTTATTCACCCGCATTGACGGATTTTGTGATTATGGCGGAACATACGTCGCA
CATGTTTATTACAGGCCCGAAAGTCATTGAACAGGTTACGGGTGAACAGATTGACGCGGAAAGTTTAGGCGGTGCGGGTA
TACATAATGTGATAAGCGGAAATGCCCACTATTCCGCACGAACGGAAAAAGAGGCTCTTTCCGCTGTGAAAACCCTGCTT
TCTTATCTCCCGCACGGCGGACAGACGGCATCACCCGTTAAAAAGGAAGACGCCAGACCGTTATTAAACACCCTCGTTCC
CGCGGACAGTTCGAAACCTTACGATGTGTTACAGGTAATAAAAGAGCTGGCGGATGACGGAACGTTTTTTGACATTCAGC
CGTATTTTGCCAAAAACATTGCTGTCGGTTTTCTGAAACTCGGACGGCGTACAGTCGGTGTTGTCGCAAACCAGCCGAAA
CACTTGGCGGGGAGCCTCACGATTGATGCCGCTGACAAAGCGTCGAGATTCATCCGTTTTTGCGACGCGTTTCATATTCC
GCTATTGACGATCGCTGATGTTCCGGGATTTCTTCCGGGCTTTCAGCAGGAACATGCGGGAATCATCCGTCACGGAGCAA
AATTGCTGTATGCTTTTGCCGAAGCGACGGTGCCGAAAGTGACGCTCATCATCAGAAAAGCTTACGGAGGCGCCTATGTC
GCCATGAATTCGAAAGGGCTCGGGGCAGATCTTGTATTCGCCTGGCCCAATGCGGAAATCGCCGTGATGGGAGCGGAAGG
CGCGGCGTCGATTTTATACAGCAGAGACATACAGGCTTCTGACGACCCGGAGAAAACGAAGCGCGAAAAAAAAGCCATAT
ACGAAAAGGAAAACGCCGGTCCGTATAAAGCGGCGGCCTGCGGAATGGTGGATGATATCATCCGGCCGGAAGACTCGAGG
AAAAAATTGATTCAGGCATTTGACATGCTTGCGCATAAGGAAGAGGAAAGACCGAAAAAAAAGCACGGTAATATACCGCT
TTAA

Upstream 100 bases:

>100_bases
AACGGAGCGGGCGGGAAGAAGATCGCATTTCTCTCTCCAAAAGAGGCGAACGGGGTCCTGATTGAGCTTTGTGAAACAAT
TGAAAAAGGAGAAACTCAAG

Downstream 100 bases:

>100_bases
ACGGAGGGAACTGAAAATGGTAAACGAAAAACGTCTGCTTGAAGAATTTCTTGAACTCGTTCAAATTGATTCAGAGACAA
AACATGAAGCGGAAATCAGC

Product: YqjD

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSMSDHIRHLNERRSFLTNGGGAEKNEKQHKKGKLTARERIDYLLDEDSFSELQPFAKSCMPGCQNAPGDGVVTGYGTID
GRPVYLFAHDFTVLGGTLGETHAEKIAAVMDLAAKNKTPIIGLNDSGGARIQEGVVSLNGYGHIFRRNVLYSGVIPQISV
ILGPCAGGAVYSPALTDFVIMAEHTSHMFITGPKVIEQVTGEQIDAESLGGAGIHNVISGNAHYSARTEKEALSAVKTLL
SYLPHGGQTASPVKKEDARPLLNTLVPADSSKPYDVLQVIKELADDGTFFDIQPYFAKNIAVGFLKLGRRTVGVVANQPK
HLAGSLTIDAADKASRFIRFCDAFHIPLLTIADVPGFLPGFQQEHAGIIRHGAKLLYAFAEATVPKVTLIIRKAYGGAYV
AMNSKGLGADLVFAWPNAEIAVMGAEGAASILYSRDIQASDDPEKTKREKKAIYEKENAGPYKAAACGMVDDIIRPEDSR
KKLIQAFDMLAHKEEERPKKKHGNIPL

Sequences:

>Translated_507_residues
MSMSDHIRHLNERRSFLTNGGGAEKNEKQHKKGKLTARERIDYLLDEDSFSELQPFAKSCMPGCQNAPGDGVVTGYGTID
GRPVYLFAHDFTVLGGTLGETHAEKIAAVMDLAAKNKTPIIGLNDSGGARIQEGVVSLNGYGHIFRRNVLYSGVIPQISV
ILGPCAGGAVYSPALTDFVIMAEHTSHMFITGPKVIEQVTGEQIDAESLGGAGIHNVISGNAHYSARTEKEALSAVKTLL
SYLPHGGQTASPVKKEDARPLLNTLVPADSSKPYDVLQVIKELADDGTFFDIQPYFAKNIAVGFLKLGRRTVGVVANQPK
HLAGSLTIDAADKASRFIRFCDAFHIPLLTIADVPGFLPGFQQEHAGIIRHGAKLLYAFAEATVPKVTLIIRKAYGGAYV
AMNSKGLGADLVFAWPNAEIAVMGAEGAASILYSRDIQASDDPEKTKREKKAIYEKENAGPYKAAACGMVDDIIRPEDSR
KKLIQAFDMLAHKEEERPKKKHGNIPL
>Mature_506_residues
SMSDHIRHLNERRSFLTNGGGAEKNEKQHKKGKLTARERIDYLLDEDSFSELQPFAKSCMPGCQNAPGDGVVTGYGTIDG
RPVYLFAHDFTVLGGTLGETHAEKIAAVMDLAAKNKTPIIGLNDSGGARIQEGVVSLNGYGHIFRRNVLYSGVIPQISVI
LGPCAGGAVYSPALTDFVIMAEHTSHMFITGPKVIEQVTGEQIDAESLGGAGIHNVISGNAHYSARTEKEALSAVKTLLS
YLPHGGQTASPVKKEDARPLLNTLVPADSSKPYDVLQVIKELADDGTFFDIQPYFAKNIAVGFLKLGRRTVGVVANQPKH
LAGSLTIDAADKASRFIRFCDAFHIPLLTIADVPGFLPGFQQEHAGIIRHGAKLLYAFAEATVPKVTLIIRKAYGGAYVA
MNSKGLGADLVFAWPNAEIAVMGAEGAASILYSRDIQASDDPEKTKREKKAIYEKENAGPYKAAACGMVDDIIRPEDSRK
KLIQAFDMLAHKEEERPKKKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=508, Percent_Identity=53.1496062992126, Blast_Score=522, Evalue=1e-148,
Organism=Homo sapiens, GI295821216, Length=531, Percent_Identity=51.2241054613936, Blast_Score=511, Evalue=1e-145,
Organism=Homo sapiens, GI11545863, Length=503, Percent_Identity=31.610337972167, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI38679971, Length=420, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38679974, Length=420, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38679977, Length=420, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679967, Length=420, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38679960, Length=420, Percent_Identity=25.2380952380952, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788655, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147359, Length=507, Percent_Identity=52.0710059171598, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI25147362, Length=507, Percent_Identity=52.465483234714, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17552936, Length=496, Percent_Identity=35.6854838709677, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24586065, Length=517, Percent_Identity=31.9148936170213, Blast_Score=228, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 54747; Mature: 54616

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSDHIRHLNERRSFLTNGGGAEKNEKQHKKGKLTARERIDYLLDEDSFSELQPFAKSC
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHH
MPGCQNAPGDGVVTGYGTIDGRPVYLFAHDFTVLGGTLGETHAEKIAAVMDLAAKNKTPI
CCCCCCCCCCCEEEEECCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCE
IGLNDSGGARIQEGVVSLNGYGHIFRRNVLYSGVIPQISVILGPCAGGAVYSPALTDFVI
EEECCCCCCHHHHCEEEECCCCHHHHHHHHHHCCHHHEEHEEECCCCCCCCCHHHHHEEE
MAEHTSHMFITGPKVIEQVTGEQIDAESLGGAGIHNVISGNAHYSARTEKEALSAVKTLL
EEECCCEEEEECHHHHHHHCCCCCCHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
SYLPHGGQTASPVKKEDARPLLNTLVPADSSKPYDVLQVIKELADDGTFFDIQPYFAKNI
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHH
AVGFLKLGRRTVGVVANQPKHLAGSLTIDAADKASRFIRFCDAFHIPLLTIADVPGFLPG
HHHHHHHCCHHEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
FQQEHAGIIRHGAKLLYAFAEATVPKVTLIIRKAYGGAYVAMNSKGLGADLVFAWPNAEI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCCCE
AVMGAEGAASILYSRDIQASDDPEKTKREKKAIYEKENAGPYKAAACGMVDDIIRPEDSR
EEEECCCHHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
KKLIQAFDMLAHKEEERPKKKHGNIPL
HHHHHHHHHHHHHHHHCHHHHCCCCCC
>Mature Secondary Structure 
SMSDHIRHLNERRSFLTNGGGAEKNEKQHKKGKLTARERIDYLLDEDSFSELQPFAKSC
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHH
MPGCQNAPGDGVVTGYGTIDGRPVYLFAHDFTVLGGTLGETHAEKIAAVMDLAAKNKTPI
CCCCCCCCCCCEEEEECCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCE
IGLNDSGGARIQEGVVSLNGYGHIFRRNVLYSGVIPQISVILGPCAGGAVYSPALTDFVI
EEECCCCCCHHHHCEEEECCCCHHHHHHHHHHCCHHHEEHEEECCCCCCCCCHHHHHEEE
MAEHTSHMFITGPKVIEQVTGEQIDAESLGGAGIHNVISGNAHYSARTEKEALSAVKTLL
EEECCCEEEEECHHHHHHHCCCCCCHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
SYLPHGGQTASPVKKEDARPLLNTLVPADSSKPYDVLQVIKELADDGTFFDIQPYFAKNI
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHH
AVGFLKLGRRTVGVVANQPKHLAGSLTIDAADKASRFIRFCDAFHIPLLTIADVPGFLPG
HHHHHHHCCHHEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
FQQEHAGIIRHGAKLLYAFAEATVPKVTLIIRKAYGGAYVAMNSKGLGADLVFAWPNAEI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCCCE
AVMGAEGAASILYSRDIQASDDPEKTKREKKAIYEKENAGPYKAAACGMVDDIIRPEDSR
EEEECCCHHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
KKLIQAFDMLAHKEEERPKKKHGNIPL
HHHHHHHHHHHHHHHHCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]