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The map label for this gene is fur [H]

Identifier: 154686595

GI number: 154686595

Start: 2252889

End: 2253338

Strand: Reverse

Name: fur [H]

Synonym: RBAM_021640

Alternate gene names: 154686595

Gene position: 2253338-2252889 (Counterclockwise)

Preceding gene: 154686596

Following gene: 154686594

Centisome position: 57.5

GC content: 43.56

Gene sequence:

>450_bases
ATGGAAAACCGTATTGATCGAATTAAAAAGCAGCTGCACTCGTCAAGCTACAAGCTTACGCCACAGCGGGAAGCAACGGT
AAGAGTGCTGCTTGAAAACGAAGAAGACCATTTAAGCGCAGAAGATGTATACCTCCTCGTAAAAGAGAAATCTCCTGAAA
TTGGTCTCGCTACAGTATACCGTACATTAGAATTATTAACAGAATTAAAAGTCGTTGATAAAATTAACTTCGGGGACGGC
GTATCCCGCTACGACCTTCGCAAAGAAGGCGCGGCTCACTTTCATCACCATTTGGTGTGCATGGAGTGCGGAGCCGTCGA
TGAAATTGAAGAAGATCTGCTTGAAGACGTTGAAGAAGTGATTGAACGTGATTGGAAATTTAAAATTAAAGATCATAGAT
TGACTTTTCACGGAATCTGCCACCGCTGCCGCGGGGATGAAACAGAGTAA

Upstream 100 bases:

>100_bases
AAAATAACACTTTTATTTATCAGTTTATAATAATTATAGTTGGAACTCTGCGCGTATTTTGTTATAATGAGTCATGGAAT
GCGGCGTAGGAGGGAAAGAC

Downstream 100 bases:

>100_bases
AAGCCTACGAACCTTTTCTGCCAGGAAAGGGTTTTTTGCTGTTTTTATGTATAAAAGCCTTTGAAATTGGCATAAGGTGT
ACTAACAGCCGCCAAAAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTELKVVDKINFGDG
VSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEVIERDWKFKIKDHRLTFHGICHRCRGDETE

Sequences:

>Translated_149_residues
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTELKVVDKINFGDG
VSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEVIERDWKFKIKDHRLTFHGICHRCRGDETE
>Mature_149_residues
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTELKVVDKINFGDG
VSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEVIERDWKFKIKDHRLTFHGICHRCRGDETE

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=35.5072463768116, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17443; Mature: 17443

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLTELKVVDKINFGDGVSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERDWKFKIKDHRLTFHGICHRCRGDETE
HHCCCCEEEECCEEHHHHHHHHCCCCCCC
>Mature Secondary Structure
MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVY
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLTELKVVDKINFGDGVSRYDLRKEGAAHFHHHLVCMECGAVDEIEEDLLEDVEEV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERDWKFKIKDHRLTFHGICHRCRGDETE
HHCCCCEEEECCEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]