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The map label for this gene is engA

Identifier: 154686532

GI number: 154686532

Start: 2196652

End: 2197962

Strand: Reverse

Name: engA

Synonym: RBAM_021000

Alternate gene names: 154686532

Gene position: 2197962-2196652 (Counterclockwise)

Preceding gene: 154686533

Following gene: 154686531

Centisome position: 56.09

GC content: 47.22

Gene sequence:

>1311_bases
ATGGGTAAACCTGTCGTAGCCATTGTCGGAAGACCGAATGTGGGAAAATCCACAATCTTTAACCGGATTGCGGGTGAAAG
AATTTCAATAGTAGAAGATACCCCCGGAGTGACGCGGGACCGGATATACAGTTCGGCGGAATGGCTGAATTATGATTTTA
ACCTGATTGATACGGGCGGAATTGATATCGGAGACGAACCGTTTCTGACACAGATCCGCCAGCAGGCTGAAATCGCCATG
GACGAGGCTGATGTGATCATCTTTATGGTGAACGGCCGCGAAGGTGTTACGTCTGCGGATGAAGAAGTGGCGAAAATACT
GTACCGGACGAAAAAACCGGTCGTATTAGCCGTTAATAAATTAGATAATACCGAAATGAGAGCGAACATCTATGACTTTT
ATGCGCTCGGCTTTGGAGAACCGTATCCGATTTCGGGCACACACGGTTTAGGATTGGGAGATTTGCTCGATGCTTGTGCC
GAGCATTTTAAAAACATTCCGGAGACGAAGTACAGTGATGATGTCGTTCAATTCTGCCTGATCGGCCGCCCGAATGTCGG
AAAATCATCCCTTGTCAATGCGATGCTCGGCGAAGAGCGGGTTATCGTGAGCAACGTAGCCGGAACGACTAGAGACGCTG
TGGATACGGCGTTCACCTACAATCAGCAGGAATTTGTAATCGTTGACACGGCGGGAATGAGAAAAAAGGGTAAAGTATAT
GAAACAACAGAAAAATACAGTGTGCTTCGGGCGTTAAAAGCCATTGACCGCTCAGACGTCGTCGGCGTTGTGCTGAATGC
AGAAGAAGGCATCCTTGAGCAGGACAAGCGGATCGCCGGATACGCCCATGAAGCCGGGAAAGCCGTCGTCATTATCGTAA
ACAAATGGGATGCCGTTGATAAAGACGAGCGCACGATGAAAGAATTTGAACAGAATATTCGGGAACATTTCCAATTTCTC
GATTACGCGCCGGTGCTGTTTATGTCGGCACTGACGACAAAGCGGATTCATACACTCATGCCTGCGATTATTAAAGCGAG
TGAAAACCACTCTCTCCGCGTGCAGACAAATGTCTTAAATGATGTCATTATGGATGCGGTCGCCATGAATCCAACTCCGA
CGCACAACGGCTCCCGTCTGAAAATTTATTATGCGACTCAAGTCGCTGTTAAGCCGCCGAGCTTCGTTGTTTTTGTCAAC
GATCCGGAACTGATGCATTTTTCTTATGAACGCTTTTTAGAAAACCGAATCCGGGACGCTTTCGGATTTGAAGGTACGCC
AATTAAAATATTTGCAAGAGCAAGAAAATAA

Upstream 100 bases:

>100_bases
TCTGTTTGAAGGGTTCTTTTCATAGCGAAGATGATTTTTAATAACCGGTTGAACAATTTTTTGTGAAAATGTAAGCGGCT
GGATTGAAAGGAAGGGTACT

Downstream 100 bases:

>100_bases
AAAGGTGTGATACAGAGATGAAAAAAGTGGCAATGCTTGGAGCGGGAAGCTGGGGCACTGCACTTTCTTTAGTGCTGGCT
GATAACGGACATCAAGTCAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLTQIRQQAEIAM
DEADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACA
EHFKNIPETKYSDDVVQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVY
ETTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVDKDERTMKEFEQNIREHFQFL
DYAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK

Sequences:

>Translated_436_residues
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLTQIRQQAEIAM
DEADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACA
EHFKNIPETKYSDDVVQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVY
ETTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVDKDERTMKEFEQNIREHFQFL
DYAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVN
DPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK
>Mature_435_residues
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLTQIRQQAEIAMD
EADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNKLDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACAE
HFKNIPETKYSDDVVQFCLIGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVYE
TTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVDKDERTMKEFEQNIREHFQFLD
YAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVND
PELMHFSYERFLENRIRDAFGFEGTPIKIFARARK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=38.4615384615385, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1788919, Length=183, Percent_Identity=32.2404371584699, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367268, Length=86, Percent_Identity=38.3720930232558, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=185, Percent_Identity=30.8108108108108, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550813, Length=183, Percent_Identity=29.5081967213115, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_BACA2 (A7Z636)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421693.1
- ProteinModelPortal:   A7Z636
- SMR:   A7Z636
- STRING:   A7Z636
- EnsemblBacteria:   EBBACT00000006950
- GeneID:   5462248
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_021000
- eggNOG:   COG1160
- GeneTree:   EBGT00070000032012
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   BAMY326423:RBAM_021000-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48743; Mature: 48612

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHEECCCEEEECCC
IDIGDEPFLTQIRQQAEIAMDEADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
LDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACAEHFKNIPETKYSDDVVQFCL
CCCCHHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHEEECCCEEEEEECCCCCCCCCEE
ETTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVD
EHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHCHHHHCCHHCCCCEEEEEEECCCCCC
KDERTMKEFEQNIREHFQFLDYAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIKIFARARK
HCCCCCCEEEEEECCC
>Mature Secondary Structure 
GKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHCCHHHEECCCEEEECCC
IDIGDEPFLTQIRQQAEIAMDEADVIIFMVNGREGVTSADEEVAKILYRTKKPVVLAVNK
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
LDNTEMRANIYDFYALGFGEPYPISGTHGLGLGDLLDACAEHFKNIPETKYSDDVVQFCL
CCCCHHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IGRPNVGKSSLVNAMLGEERVIVSNVAGTTRDAVDTAFTYNQQEFVIVDTAGMRKKGKVY
CCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHEEECCCEEEEEECCCCCCCCCEE
ETTEKYSVLRALKAIDRSDVVGVVLNAEEGILEQDKRIAGYAHEAGKAVVIIVNKWDAVD
EHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHCHHHHCCHHCCCCEEEEEEECCCCCC
KDERTMKEFEQNIREHFQFLDYAPVLFMSALTTKRIHTLMPAIIKASENHSLRVQTNVLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
DVIMDAVAMNPTPTHNGSRLKIYYATQVAVKPPSFVVFVNDPELMHFSYERFLENRIRDA
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHH
FGFEGTPIKIFARARK
HCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA