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The map label for this gene is gpsA

Identifier: 154686531

GI number: 154686531

Start: 2195597

End: 2196634

Strand: Reverse

Name: gpsA

Synonym: RBAM_020990

Alternate gene names: 154686531

Gene position: 2196634-2195597 (Counterclockwise)

Preceding gene: 154686532

Following gene: 154686530

Centisome position: 56.06

GC content: 48.84

Gene sequence:

>1038_bases
ATGAAAAAAGTGGCAATGCTTGGAGCGGGAAGCTGGGGCACTGCACTTTCTTTAGTGCTGGCTGATAACGGACATCAAGT
CATGATGTGGGGACACCGTGCCGAATTGATCGATCAAATCAACGAACTGCATGAAAACAAAGATTACCTGCCGGGGGTGG
AGCTATCAAGTTCTATCATCGGTACAGCTGATTTAAGCGAGGCTTTAAAAGGAGCTGACTTCATCATTGTGGCAGTTCCG
ACAAAAGCCATTCGGGAAGTGCTGAAAAAGGCTCTGCCGTACATCCCGAAACAATCGATTTTTGTTCATGTCAGCAAGGG
AATTGAGCCGGATTCGCTTCTCCGTATTTCAGAATTAATGGAAGAGGAGCTGCCTGAGGAGTACAGAAAAGACATCGTCG
TGCTTTCAGGGCCGAGCCACGCTGAGGAAGTCGGATTAAGACACCCGACGACTGTTACATCATCTTCAAAAAATATCAAG
GCTGCAGAAGCGGTTCAGGATTTATTCATGAACCAGCATTTCCGCGTCTATACCAATCCGGATATGATCGGTGTGGAAAT
AGGGGGAGCGTTAAAGAATATCATCGCTCTTGCAGCGGGGATTACAGACGGATTGGGATACGGAGATAATGCAAAAGCGG
CCTTAATCACCCGAGGTCTTGCTGAAATCGCCAGACTCGGCACAAAGATGGGCGGAAATCCGCTCACCTTTTCCGGCCTG
ACCGGCGTAGGCGATTTAATCGTGACGTGTACAAGCGTTCATTCCCGAAACTGGCGCGCCGGCAACCTGCTCGGCAAAGG
ATATAAGCTGGAAGCTGTCCTGGATAAGATGGGGATGGTTGTTGAAGGCGTGCGGACGACGAAAGCTGCGTATCAGCTGT
CTCAAAAATACCAAGTGAAAATGCCGATCACAGAGGCGCTTCACCAAGTATTATTTAACGGGCAGAAGGTAGAAACGGCC
GTAGAATCCTTAATGGCCAGAGTGAAAACCCATGAGATGGAAGACTTGGTCAACACATTCGAAAACCGGGTGAAGTGA

Upstream 100 bases:

>100_bases
AACGCTTTTTAGAAAACCGAATCCGGGACGCTTTCGGATTTGAAGGTACGCCAATTAAAATATTTGCAAGAGCAAGAAAA
TAAAAAGGTGTGATACAGAG

Downstream 100 bases:

>100_bases
CAATAACATGCCGTCAGCATATTCTGAAGTGACGAAAGTCCAAAACGCAGAACTCTCCGGCTGAAATCGCTTAAAACATT
TGCTGATTTAGGCAGAAGAG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKKVAMLGAGSWGTALSLVLADNGHQVMMWGHRAELIDQINELHENKDYLPGVELSSSIIGTADLSEALKGADFIIVAVP
TKAIREVLKKALPYIPKQSIFVHVSKGIEPDSLLRISELMEEELPEEYRKDIVVLSGPSHAEEVGLRHPTTVTSSSKNIK
AAEAVQDLFMNQHFRVYTNPDMIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPLTFSGL
TGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEAVLDKMGMVVEGVRTTKAAYQLSQKYQVKMPITEALHQVLFNGQKVETA
VESLMARVKTHEMEDLVNTFENRVK

Sequences:

>Translated_345_residues
MKKVAMLGAGSWGTALSLVLADNGHQVMMWGHRAELIDQINELHENKDYLPGVELSSSIIGTADLSEALKGADFIIVAVP
TKAIREVLKKALPYIPKQSIFVHVSKGIEPDSLLRISELMEEELPEEYRKDIVVLSGPSHAEEVGLRHPTTVTSSSKNIK
AAEAVQDLFMNQHFRVYTNPDMIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPLTFSGL
TGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEAVLDKMGMVVEGVRTTKAAYQLSQKYQVKMPITEALHQVLFNGQKVETA
VESLMARVKTHEMEDLVNTFENRVK
>Mature_345_residues
MKKVAMLGAGSWGTALSLVLADNGHQVMMWGHRAELIDQINELHENKDYLPGVELSSSIIGTADLSEALKGADFIIVAVP
TKAIREVLKKALPYIPKQSIFVHVSKGIEPDSLLRISELMEEELPEEYRKDIVVLSGPSHAEEVGLRHPTTVTSSSKNIK
AAEAVQDLFMNQHFRVYTNPDMIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPLTFSGL
TGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEAVLDKMGMVVEGVRTTKAAYQLSQKYQVKMPITEALHQVLFNGQKVETA
VESLMARVKTHEMEDLVNTFENRVK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=346, Percent_Identity=32.0809248554913, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI33695088, Length=345, Percent_Identity=30.4347826086957, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=40.6060606060606, Blast_Score=270, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI32564399, Length=345, Percent_Identity=31.0144927536232, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI193210136, Length=353, Percent_Identity=31.1614730878187, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564403, Length=353, Percent_Identity=31.1614730878187, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17507425, Length=360, Percent_Identity=28.3333333333333, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193210134, Length=345, Percent_Identity=28.4057971014493, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324513, Length=350, Percent_Identity=28.2857142857143, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.1524926686217, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17136202, Length=356, Percent_Identity=32.0224719101124, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17136204, Length=344, Percent_Identity=32.2674418604651, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17136200, Length=344, Percent_Identity=32.2674418604651, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI22026922, Length=348, Percent_Identity=25.5747126436782, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45551945, Length=264, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648969, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BACA2 (A7Z635)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421692.1
- ProteinModelPortal:   A7Z635
- SMR:   A7Z635
- STRING:   A7Z635
- EnsemblBacteria:   EBBACT00000007030
- GeneID:   5462288
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020990
- eggNOG:   COG0240
- GeneTree:   EBGT00050000002224
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- BioCyc:   BAMY326423:RBAM_020990-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 37501; Mature: 37501

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 106-106 BINDING 106-106 BINDING 141-141 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVAMLGAGSWGTALSLVLADNGHQVMMWGHRAELIDQINELHENKDYLPGVELSSSII
CCCEEEEECCCHHHEEEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GTADLSEALKGADFIIVAVPTKAIREVLKKALPYIPKQSIFVHVSKGIEPDSLLRISELM
CHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHH
EEELPEEYRKDIVVLSGPSHAEEVGLRHPTTVTSSSKNIKAAEAVQDLFMNQHFRVYTNP
HHHCCHHHHCCEEEEECCCCHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCCCEEEEECC
DMIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPLTFSGL
CEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
TGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEAVLDKMGMVVEGVRTTKAAYQLSQKYQVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
MPITEALHQVLFNGQKVETAVESLMARVKTHEMEDLVNTFENRVK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVAMLGAGSWGTALSLVLADNGHQVMMWGHRAELIDQINELHENKDYLPGVELSSSII
CCCEEEEECCCHHHEEEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GTADLSEALKGADFIIVAVPTKAIREVLKKALPYIPKQSIFVHVSKGIEPDSLLRISELM
CHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHH
EEELPEEYRKDIVVLSGPSHAEEVGLRHPTTVTSSSKNIKAAEAVQDLFMNQHFRVYTNP
HHHCCHHHHCCEEEEECCCCHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCCCEEEEECC
DMIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTKMGGNPLTFSGL
CEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
TGVGDLIVTCTSVHSRNWRAGNLLGKGYKLEAVLDKMGMVVEGVRTTKAAYQLSQKYQVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
MPITEALHQVLFNGQKVETAVESLMARVKTHEMEDLVNTFENRVK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA