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The map label for this gene is cheR [H]

Identifier: 154686520

GI number: 154686520

Start: 2186857

End: 2187627

Strand: Reverse

Name: cheR [H]

Synonym: RBAM_020880

Alternate gene names: 154686520

Gene position: 2187627-2186857 (Counterclockwise)

Preceding gene: 154686521

Following gene: 154686519

Centisome position: 55.83

GC content: 42.02

Gene sequence:

>771_bases
ATGGAGCCTTACGACATTTTTATCACCAAGTGGAAACAAATAACCGGCGTTGATTTATCTTTATACAAAGAAGCACAGAT
GAAAAGGCGGCTGACGTCCCTTTATGAAAAGAAGGGGTTCAGAGATTTTCAGGAATTTGCCGCCGCTTTGGAAAAGGACA
AGCTTTTATTAAATGAAACATTGGACAGAATGACGATCAATGTTTCTGAATTTTACCGAAATTATAAACGGTGGGAAGTT
CTTGAAACCTCAATTCTCCCATTAATAAAGCATAACAAACCGTTAAAAATATGGAGTGCGGCCTGTTCAACGGGAGAGGA
GCCCTATACTTTGGCGATGATTCTCAATCAGCAGACGGGACTGGCCGGATTTGATATATTGGCGACAGATATTGATGAAA
AGGCGCTGAGCAAAGCCAAGCGGGGCATCTATCAGGAACGCTCGCTTCAAGAGGTGCCGGCTTCCGTGAAAAGCCGTTAT
TTCACTAAGCAGGCTGACAACAGTTATCAAGTAAAACAAGAGATTCAGAACAACATCCGGTTTAAGCGGCACAACCTGCT
TGCCGACAGCTATGAACAGGATTTTGATCTGATCGTCTGCCGCAACGTCTTTATTTATTTTACTGAAAAAGCAAAAGAAG
AGCTGTATGTGAAAATGGCGGGCAGTCTGAAAAAGAACGGAATTCTGTTTGTCGGCAGTACAGAACAAATTTTCAGCCCG
GAAAAATTCGGCCTTGAGAGCACTGATACATTTTTTTATCAAAAAAGATAG

Upstream 100 bases:

>100_bases
ACAAATCAGCCCGCGGGCTGATTTTTTTATTGAAATCGTACAATTTCGACAGAAAACAGGCTATACTAGGACAAAAGACA
GCGAGATTGGGAGAGAAGCA

Downstream 100 bases:

>100_bases
AAGACATTTAATGAAAACTTGTGGTATAGTTTTACTTAAAAGCGTTAATGCGATGAAGGGAGAAGAAAGAAATGAGATAC
TTAACAGCCGGAGAATCACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEPYDIFITKWKQITGVDLSLYKEAQMKRRLTSLYEKKGFRDFQEFAAALEKDKLLLNETLDRMTINVSEFYRNYKRWEV
LETSILPLIKHNKPLKIWSAACSTGEEPYTLAMILNQQTGLAGFDILATDIDEKALSKAKRGIYQERSLQEVPASVKSRY
FTKQADNSYQVKQEIQNNIRFKRHNLLADSYEQDFDLIVCRNVFIYFTEKAKEELYVKMAGSLKKNGILFVGSTEQIFSP
EKFGLESTDTFFYQKR

Sequences:

>Translated_256_residues
MEPYDIFITKWKQITGVDLSLYKEAQMKRRLTSLYEKKGFRDFQEFAAALEKDKLLLNETLDRMTINVSEFYRNYKRWEV
LETSILPLIKHNKPLKIWSAACSTGEEPYTLAMILNQQTGLAGFDILATDIDEKALSKAKRGIYQERSLQEVPASVKSRY
FTKQADNSYQVKQEIQNNIRFKRHNLLADSYEQDFDLIVCRNVFIYFTEKAKEELYVKMAGSLKKNGILFVGSTEQIFSP
EKFGLESTDTFFYQKR
>Mature_256_residues
MEPYDIFITKWKQITGVDLSLYKEAQMKRRLTSLYEKKGFRDFQEFAAALEKDKLLLNETLDRMTINVSEFYRNYKRWEV
LETSILPLIKHNKPLKIWSAACSTGEEPYTLAMILNQQTGLAGFDILATDIDEKALSKAKRGIYQERSLQEVPASVKSRY
FTKQADNSYQVKQEIQNNIRFKRHNLLADSYEQDFDLIVCRNVFIYFTEKAKEELYVKMAGSLKKNGILFVGSTEQIFSP
EKFGLESTDTFFYQKR

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=239, Percent_Identity=31.7991631799163, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 29996; Mature: 29996

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPYDIFITKWKQITGVDLSLYKEAQMKRRLTSLYEKKGFRDFQEFAAALEKDKLLLNET
CCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LDRMTINVSEFYRNYKRWEVLETSILPLIKHNKPLKIWSAACSTGEEPYTLAMILNQQTG
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
LAGFDILATDIDEKALSKAKRGIYQERSLQEVPASVKSRYFTKQADNSYQVKQEIQNNIR
CCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
FKRHNLLADSYEQDFDLIVCRNVFIYFTEKAKEELYVKMAGSLKKNGILFVGSTEQIFSP
CHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCHHHCCC
EKFGLESTDTFFYQKR
HHCCCCCCCCEEEECC
>Mature Secondary Structure
MEPYDIFITKWKQITGVDLSLYKEAQMKRRLTSLYEKKGFRDFQEFAAALEKDKLLLNET
CCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LDRMTINVSEFYRNYKRWEVLETSILPLIKHNKPLKIWSAACSTGEEPYTLAMILNQQTG
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
LAGFDILATDIDEKALSKAKRGIYQERSLQEVPASVKSRYFTKQADNSYQVKQEIQNNIR
CCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
FKRHNLLADSYEQDFDLIVCRNVFIYFTEKAKEELYVKMAGSLKKNGILFVGSTEQIFSP
CHHHHHHHHCCCCCCCEEEECCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCHHHCCC
EKFGLESTDTFFYQKR
HHCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8244966; 9384377; 10568751 [H]