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The map label for this gene is trpD

Identifier: 154686515

GI number: 154686515

Start: 2181386

End: 2182402

Strand: Reverse

Name: trpD

Synonym: RBAM_020830

Alternate gene names: 154686515

Gene position: 2182402-2181386 (Counterclockwise)

Preceding gene: 154686516

Following gene: 154686514

Centisome position: 55.69

GC content: 50.05

Gene sequence:

>1017_bases
ATGAACAAATTTCTGCAATCGTGCGTTAATGGCCGTACGCTGAAAACCGGAGAAGCCGAAAAGCTGATGGAGATGATGAT
GAACGGGGACATGTCGCAGTCTGAGATCGGCGGGATTTTATCGGTGTTAGCCCACCGAGGTGAAACGGCGGAGGAGCTTG
CCGGATTTGTAAAAGTGATGCGGGCGCGGGCACAGACATCAGGTGGCTTGGCGGATGTCGTTGATACGTGCGGAACAGGC
GGAGACGGGATTTCTACGTTTAACATATCCACGGCAGCGGCGATTACAGCTTCTGCTGCCGGAGCTAAAGTTGCCAAGCA
CGGAAATCGCTCCGTTTCGTCTAAAAGCGGCAGCGCGGATGTGCTGGAAAAACTGGGGGTTTCCATTCAAGCCACTCCAG
AAAGCGTTAAACGCAGCATTGAAATGAAACAAATGGGGTTTTTGTTTGCGCCGCTGTTTCATTCGTCAATGAAGCACGTC
GCCGCCGCAAGAAAAGAGCTTGGCTTCCGAACCGTATTTAATCTGCTGGGCCCGCTCAGCAACCCGCTGCAGGTGAAGCG
GCAGGTGATCGGCGTCTATTCATTTGATAAAGCGCGCCTGATGGCAAGCGCGTTGGAACAATTTGATGTCAGACACGTCA
TGCTTGTGTCGGCCCGTGACGGATTAGATGAACTGTCCATCACAGCACCGACCGATATTATTGAACTGAAAAACGGTGAA
CGTCTGGAATATTCCGTTTCACCTGAACAATTCGGTTTTGCAGAAGGTTCACTAAAGGATATTCAAGTGAGTTCATCGGA
AGAAAGCGCGCTCCTCATTCAGAATATTTTTGCAAATAAAGCTCCGTCATCCGCTCTGCATATTACCGCCTTAAATGCGG
GCGCGGCCATTTATACGGCAGGTCTTGCAAACGATCTGAAAGAAGGAACGAAAACCGCCTTAGAAGCGATTCAAAACGGA
GATGCCAAAAGGCAGCTCGAACGTCTGAAACAGAAAGAGGAAGAAATGTATGCTTGA

Upstream 100 bases:

>100_bases
CCGGAAGCCGAATATGAAGAAAGCTGTAACAAAGCGGGGGCGCTTTTAAAAACGATTCAAATCGCAGAAGACATCTTTTC
TGGCGGGGAGGAGAAGACGG

Downstream 100 bases:

>100_bases
TCAAATCATTCAGCAGAAAAAAGAAGAAATCAAATCCATCGTGCTGCCGGAAACCTGTCAAATTGAACGGAGATCCTTTA
AAAAAGCGCTCCAGAACCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNKFLQSCVNGRTLKTGEAEKLMEMMMNGDMSQSEIGGILSVLAHRGETAEELAGFVKVMRARAQTSGGLADVVDTCGTG
GDGISTFNISTAAAITASAAGAKVAKHGNRSVSSKSGSADVLEKLGVSIQATPESVKRSIEMKQMGFLFAPLFHSSMKHV
AAARKELGFRTVFNLLGPLSNPLQVKRQVIGVYSFDKARLMASALEQFDVRHVMLVSARDGLDELSITAPTDIIELKNGE
RLEYSVSPEQFGFAEGSLKDIQVSSSEESALLIQNIFANKAPSSALHITALNAGAAIYTAGLANDLKEGTKTALEAIQNG
DAKRQLERLKQKEEEMYA

Sequences:

>Translated_338_residues
MNKFLQSCVNGRTLKTGEAEKLMEMMMNGDMSQSEIGGILSVLAHRGETAEELAGFVKVMRARAQTSGGLADVVDTCGTG
GDGISTFNISTAAAITASAAGAKVAKHGNRSVSSKSGSADVLEKLGVSIQATPESVKRSIEMKQMGFLFAPLFHSSMKHV
AAARKELGFRTVFNLLGPLSNPLQVKRQVIGVYSFDKARLMASALEQFDVRHVMLVSARDGLDELSITAPTDIIELKNGE
RLEYSVSPEQFGFAEGSLKDIQVSSSEESALLIQNIFANKAPSSALHITALNAGAAIYTAGLANDLKEGTKTALEAIQNG
DAKRQLERLKQKEEEMYA
>Mature_338_residues
MNKFLQSCVNGRTLKTGEAEKLMEMMMNGDMSQSEIGGILSVLAHRGETAEELAGFVKVMRARAQTSGGLADVVDTCGTG
GDGISTFNISTAAAITASAAGAKVAKHGNRSVSSKSGSADVLEKLGVSIQATPESVKRSIEMKQMGFLFAPLFHSSMKHV
AAARKELGFRTVFNLLGPLSNPLQVKRQVIGVYSFDKARLMASALEQFDVRHVMLVSARDGLDELSITAPTDIIELKNGE
RLEYSVSPEQFGFAEGSLKDIQVSSSEESALLIQNIFANKAPSSALHITALNAGAAIYTAGLANDLKEGTKTALEAIQNG
DAKRQLERLKQKEEEMYA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=336, Percent_Identity=31.8452380952381, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320561, Length=270, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=9e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACA2 (A7Z619)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421676.1
- STRING:   A7Z619
- EnsemblBacteria:   EBBACT00000005702
- GeneID:   5462029
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020830
- eggNOG:   COG0547
- GeneTree:   EBGT00050000002544
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   BAMY326423:RBAM_020830-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFLQSCVNGRTLKTGEAEKLMEMMMNGDMSQSEIGGILSVLAHRGETAEELAGFVKVM
CCHHHHHHHCCCEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RARAQTSGGLADVVDTCGTGGDGISTFNISTAAAITASAAGAKVAKHGNRSVSSKSGSAD
HHHHHCCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VLEKLGVSIQATPESVKRSIEMKQMGFLFAPLFHSSMKHVAAARKELGFRTVFNLLGPLS
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPLQVKRQVIGVYSFDKARLMASALEQFDVRHVMLVSARDGLDELSITAPTDIIELKNGE
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHEEEEECCCCCCCCEECCCCCEEECCCCC
RLEYSVSPEQFGFAEGSLKDIQVSSSEESALLIQNIFANKAPSSALHITALNAGAAIYTA
EEEEECCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHH
GLANDLKEGTKTALEAIQNGDAKRQLERLKQKEEEMYA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKFLQSCVNGRTLKTGEAEKLMEMMMNGDMSQSEIGGILSVLAHRGETAEELAGFVKVM
CCHHHHHHHCCCEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RARAQTSGGLADVVDTCGTGGDGISTFNISTAAAITASAAGAKVAKHGNRSVSSKSGSAD
HHHHHCCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VLEKLGVSIQATPESVKRSIEMKQMGFLFAPLFHSSMKHVAAARKELGFRTVFNLLGPLS
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPLQVKRQVIGVYSFDKARLMASALEQFDVRHVMLVSARDGLDELSITAPTDIIELKNGE
CHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHEEEEECCCCCCCCEECCCCCEEECCCCC
RLEYSVSPEQFGFAEGSLKDIQVSSSEESALLIQNIFANKAPSSALHITALNAGAAIYTA
EEEEECCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHH
GLANDLKEGTKTALEAIQNGDAKRQLERLKQKEEEMYA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA