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The map label for this gene is trpB

Identifier: 154686512

GI number: 154686512

Start: 2178800

End: 2180002

Strand: Reverse

Name: trpB

Synonym: RBAM_020800

Alternate gene names: 154686512

Gene position: 2180002-2178800 (Counterclockwise)

Preceding gene: 154686513

Following gene: 154686511

Centisome position: 55.63

GC content: 48.63

Gene sequence:

>1203_bases
ATGTATCCATATCCAAATGAAATCGGAAGATACGGCGAATTCGGCGGCAAATTTGTCCCTGAAACATTGATGCGGCCCCT
TGAGGAAATCGAAACGGCTTTCAAAGAATTAAAGAATGATCCCGTTTTTCATGCCGAATATAAAAAGCTATTGTTTGATT
ACTCCGGAAGACCGACCGCATTAACGTTCGCAGACAGGGTGTCAGAGTATTTGGGAGGGGCGAAAATCTATCTGAAAAGA
GAAGATTTAAACCATACCGGCTCTCATAAAATTAACAACGCGTTAGGCCAGATTCTGCTTGCCAAAAAGATGGGCAAAAC
GAAAATCATCGCCGAAACCGGTGCGGGACAGCACGGTGTGGCTGCCGCAACAGCCGCTGCAAAATTCGGTTTTAAGTGTA
CGGTTTTTATGGGTGAAGAAGACGTTGCGCGTCAGTCGCTGAACGTATTCCGGATGAAACTGCTCGGCGCGGAAGTGGTG
CCGGTCACAAGCGGCAACGGCACGCTGAAAGATGCGACGAATGAGGCGATCAGGTATTGGGTCCAGCATTGTGAAGATCA
TTTCTACCTTATCGGTTCTGTAGTGGGGCCGCATCCGTATCCGTATATCGTTCGCGAATTTCAGAAAATCATCGGCGAGG
AAGCGAAAGAACAGCTCCGCCGGGTTGAAGGAACACTCCCGGACAAGGTTGTTGCATGTGTCGGCGGCGGAAGCAATGCG
ATGGGCATTTTTCAGGCCTTTTTAGACGAAGATACTGAGCTGATCGGCGCCGAGGCTGCCGGAAAAGGAATTGATACACC
GCTGCATGCGGCAACGATCGCAAAAGGGACGCTCGGGGTGATTCACGGTTCAATGACCTATTTAATACAAGATCAATACG
GGCAGATTATCGAACCGTATTCCATTTCAGCAGGCCTTGATTACCCGGGGATCGGTCCTGAGCATGCCTATCTGCATAAA
AGCGGCCGTGTAACGTACGAAAGCGTGACAGACGATGAAGCGATTGCCGCGTTACGTCTGCTTTCTGAAACAGAAGGTAT
TCTTCCGGCTATTGAATCTGCCCACGCTCTGGCCAAAGCGTTTGAAATGGCAAAAGACATGGATAAAGACAAAATCATTC
TCGTCAGTTTGTCGGGAAGAGGAGATAAAGATGTTCATACGCTGATGAATGTTTTGGAAAACGGGGTGGGGACACATGTT
TAA

Upstream 100 bases:

>100_bases
AGATCGCGTCCGTGCGGTATAGATCTTGCCAGCGGAATTGAAAAAAACGGACAAAAGGATCAAACACTGATCCGGCTTTT
AGAAGAAAGGATGAACCACT

Downstream 100 bases:

>100_bases
TCTGCGAGATTCTGAAAAATTATTTATCCCTTTTATTACGGCTGGCGATCCGCTTCCTGACATTTCTGTTGAGCTGGCAA
TATCATTGCAGAATGCAGGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYPYPNEIGRYGEFGGKFVPETLMRPLEEIETAFKELKNDPVFHAEYKKLLFDYSGRPTALTFADRVSEYLGGAKIYLKR
EDLNHTGSHKINNALGQILLAKKMGKTKIIAETGAGQHGVAAATAAAKFGFKCTVFMGEEDVARQSLNVFRMKLLGAEVV
PVTSGNGTLKDATNEAIRYWVQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEEAKEQLRRVEGTLPDKVVACVGGGSNA
MGIFQAFLDEDTELIGAEAAGKGIDTPLHAATIAKGTLGVIHGSMTYLIQDQYGQIIEPYSISAGLDYPGIGPEHAYLHK
SGRVTYESVTDDEAIAALRLLSETEGILPAIESAHALAKAFEMAKDMDKDKIILVSLSGRGDKDVHTLMNVLENGVGTHV

Sequences:

>Translated_400_residues
MYPYPNEIGRYGEFGGKFVPETLMRPLEEIETAFKELKNDPVFHAEYKKLLFDYSGRPTALTFADRVSEYLGGAKIYLKR
EDLNHTGSHKINNALGQILLAKKMGKTKIIAETGAGQHGVAAATAAAKFGFKCTVFMGEEDVARQSLNVFRMKLLGAEVV
PVTSGNGTLKDATNEAIRYWVQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEEAKEQLRRVEGTLPDKVVACVGGGSNA
MGIFQAFLDEDTELIGAEAAGKGIDTPLHAATIAKGTLGVIHGSMTYLIQDQYGQIIEPYSISAGLDYPGIGPEHAYLHK
SGRVTYESVTDDEAIAALRLLSETEGILPAIESAHALAKAFEMAKDMDKDKIILVSLSGRGDKDVHTLMNVLENGVGTHV
>Mature_400_residues
MYPYPNEIGRYGEFGGKFVPETLMRPLEEIETAFKELKNDPVFHAEYKKLLFDYSGRPTALTFADRVSEYLGGAKIYLKR
EDLNHTGSHKINNALGQILLAKKMGKTKIIAETGAGQHGVAAATAAAKFGFKCTVFMGEEDVARQSLNVFRMKLLGAEVV
PVTSGNGTLKDATNEAIRYWVQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEEAKEQLRRVEGTLPDKVVACVGGGSNA
MGIFQAFLDEDTELIGAEAAGKGIDTPLHAATIAKGTLGVIHGSMTYLIQDQYGQIIEPYSISAGLDYPGIGPEHAYLHK
SGRVTYESVTDDEAIAALRLLSETEGILPAIESAHALAKAFEMAKDMDKDKIILVSLSGRGDKDVHTLMNVLENGVGTHV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=54.5454545454545, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=55.5844155844156, Blast_Score=454, Evalue=1e-128,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_BACA2 (A7Z616)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421673.1
- ProteinModelPortal:   A7Z616
- SMR:   A7Z616
- STRING:   A7Z616
- EnsemblBacteria:   EBBACT00000007719
- GeneID:   5460944
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020800
- eggNOG:   COG0133
- GeneTree:   EBGT00050000001631
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- BioCyc:   BAMY326423:RBAM_020800-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43579; Mature: 43579

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPYPNEIGRYGEFGGKFVPETLMRPLEEIETAFKELKNDPVFHAEYKKLLFDYSGRPTA
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCE
LTFADRVSEYLGGAKIYLKREDLNHTGSHKINNALGQILLAKKMGKTKIIAETGAGQHGV
EHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCH
AAATAAAKFGFKCTVFMGEEDVARQSLNVFRMKLLGAEVVPVTSGNGTLKDATNEAIRYW
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
VQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEEAKEQLRRVEGTLPDKVVACVGGGSNA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
MGIFQAFLDEDTELIGAEAAGKGIDTPLHAATIAKGTLGVIHGSMTYLIQDQYGQIIEPY
HHHHHHHHCCCHHEECCHHCCCCCCCCHHHHHHHCCHHHHHCCCHHEEEECCCCCEECCC
SISAGLDYPGIGPEHAYLHKSGRVTYESVTDDEAIAALRLLSETEGILPAIESAHALAKA
CCCCCCCCCCCCCCHHEEECCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FEMAKDMDKDKIILVSLSGRGDKDVHTLMNVLENGVGTHV
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYPYPNEIGRYGEFGGKFVPETLMRPLEEIETAFKELKNDPVFHAEYKKLLFDYSGRPTA
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCE
LTFADRVSEYLGGAKIYLKREDLNHTGSHKINNALGQILLAKKMGKTKIIAETGAGQHGV
EHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCH
AAATAAAKFGFKCTVFMGEEDVARQSLNVFRMKLLGAEVVPVTSGNGTLKDATNEAIRYW
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
VQHCEDHFYLIGSVVGPHPYPYIVREFQKIIGEEAKEQLRRVEGTLPDKVVACVGGGSNA
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
MGIFQAFLDEDTELIGAEAAGKGIDTPLHAATIAKGTLGVIHGSMTYLIQDQYGQIIEPY
HHHHHHHHCCCHHEECCHHCCCCCCCCHHHHHHHCCHHHHHCCCHHEEEECCCCCEECCC
SISAGLDYPGIGPEHAYLHKSGRVTYESVTDDEAIAALRLLSETEGILPAIESAHALAKA
CCCCCCCCCCCCCCHHEEECCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FEMAKDMDKDKIILVSLSGRGDKDVHTLMNVLENGVGTHV
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA