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The map label for this gene is bsaA [H]

Identifier: 154686436

GI number: 154686436

Start: 2110271

End: 2110759

Strand: Reverse

Name: bsaA [H]

Synonym: RBAM_020040

Alternate gene names: 154686436

Gene position: 2110759-2110271 (Counterclockwise)

Preceding gene: 154686440

Following gene: 154686435

Centisome position: 53.87

GC content: 46.01

Gene sequence:

>489_bases
ATGACAATTTACGATATAAACGTACGGACCATAACAGGCGAAGACATGACGCTATCGGCTTACAGAGGCAAGGTGATGAT
CATTGTGAATACAGCAAGCAAATGCGGATTCACATCCCAGCTCAAGCAGCTTCAGGAGCTCTATGATACATATCGGGAGG
AAGGTCTTGAAATATTGGGATTTCCCTGCAACCAATTCATGAACCAAGAACCTGGAAACGAAGCGGAAATTCAAGAGTTC
TGTGTGAAAAACTACGGAGTCACATTCCCGATGTTTGCGAAAGTTGATGTCAATGGAGCAGACGCTCATCCTCTCTTCAC
ATATCTGACGGAACAGGCGAAGGGGATGCTCGGCACAAAAGCGGTCAAATGGAATTTCACTAAGTTTATCGTGGACCGAA
ACGGTAAAGTCACCGGGCGTTTTTCACCGAACGTCAACCCAAAAGAGCTTGAAGATACGGTACAGAGGCTTTTGGCCGAT
AAGAGGTGA

Upstream 100 bases:

>100_bases
AAAAACGTTTTCCGTTAAGTGGAAGGAAAAAGCGGTTGCCGTTTGTTTTGCAGTGTAAAACAGGTAAAATAAATGAAGAA
TGTAAAAAGGAGGGCCGCAG

Downstream 100 bases:

>100_bases
TACGGTGAACGAAAAAGAGCAGCTGGAAAGCGTCAGGAATTGGGTCAAAGAAAAGCTTATCAATGAACGAACGGGCCATG
ACTGGCTTCATATTTCCCGG

Product: BsaA

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTIYDINVRTITGEDMTLSAYRGKVMIIVNTASKCGFTSQLKQLQELYDTYREEGLEILGFPCNQFMNQEPGNEAEIQEF
CVKNYGVTFPMFAKVDVNGADAHPLFTYLTEQAKGMLGTKAVKWNFTKFIVDRNGKVTGRFSPNVNPKELEDTVQRLLAD
KR

Sequences:

>Translated_162_residues
MTIYDINVRTITGEDMTLSAYRGKVMIIVNTASKCGFTSQLKQLQELYDTYREEGLEILGFPCNQFMNQEPGNEAEIQEF
CVKNYGVTFPMFAKVDVNGADAHPLFTYLTEQAKGMLGTKAVKWNFTKFIVDRNGKVTGRFSPNVNPKELEDTVQRLLAD
KR
>Mature_161_residues
TIYDINVRTITGEDMTLSAYRGKVMIIVNTASKCGFTSQLKQLQELYDTYREEGLEILGFPCNQFMNQEPGNEAEIQEFC
VKNYGVTFPMFAKVDVNGADAHPLFTYLTEQAKGMLGTKAVKWNFTKFIVDRNGKVTGRFSPNVNPKELEDTVQRLLADK
R

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=153, Percent_Identity=46.4052287581699, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI90903240, Length=153, Percent_Identity=46.4052287581699, Blast_Score=134, Evalue=4e-32,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=40.3846153846154, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI192455698, Length=143, Percent_Identity=36.3636363636364, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=34.4262295081967, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4557629, Length=161, Percent_Identity=34.1614906832298, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI6006001, Length=154, Percent_Identity=36.3636363636364, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI33186887, Length=154, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=41.3173652694611, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=161, Percent_Identity=46.583850931677, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17535473, Length=161, Percent_Identity=45.3416149068323, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=41.7721518987342, Blast_Score=142, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=166, Percent_Identity=44.578313253012, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.3558282208589, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.1288343558282, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=40, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=40.7894736842105, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=50, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=51.8987341772152, Blast_Score=184, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6322228, Length=148, Percent_Identity=50.6756756756757, Blast_Score=174, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=147, Percent_Identity=46.2585034013605, Blast_Score=145, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=40.8805031446541, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=40.8805031446541, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=40.8805031446541, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI85726443, Length=161, Percent_Identity=38.5093167701863, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18394; Mature: 18263

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYDINVRTITGEDMTLSAYRGKVMIIVNTASKCGFTSQLKQLQELYDTYREEGLEILG
CEEEEEEEEEECCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
FPCNQFMNQEPGNEAEIQEFCVKNYGVTFPMFAKVDVNGADAHPLFTYLTEQAKGMLGTK
CCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCE
AVKWNFTKFIVDRNGKVTGRFSPNVNPKELEDTVQRLLADKR
EEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIYDINVRTITGEDMTLSAYRGKVMIIVNTASKCGFTSQLKQLQELYDTYREEGLEILG
EEEEEEEEEECCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
FPCNQFMNQEPGNEAEIQEFCVKNYGVTFPMFAKVDVNGADAHPLFTYLTEQAKGMLGTK
CCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCE
AVKWNFTKFIVDRNGKVTGRFSPNVNPKELEDTVQRLLADKR
EEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]