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The map label for this gene is bioW [H]

Identifier: 154686262

GI number: 154686262

Start: 1918338

End: 1919108

Strand: Reverse

Name: bioW [H]

Synonym: RBAM_018290

Alternate gene names: 154686262

Gene position: 1919108-1918338 (Counterclockwise)

Preceding gene: 154686266

Following gene: 154686261

Centisome position: 48.97

GC content: 48.77

Gene sequence:

>771_bases
ATGCGGGAAGAAACCTATTACAGCGTCAGAATGAGAGCTTCCCGAAACGCCCCCCATGAGCAGGGCGGAAAACACATTTC
CGGCGGAGAACGGCTCATCACTTACAGCGGTTTACAGGAAGCGGTAGATGGCTTATTACATAAAGGCTTCTCGCACTCAA
GAGGGATACCTGATTTTATGCAGATTCAGCTTGAAAGCATTAATGAACCGATCGAAACGATCCGCCCTTTGCCGGTTGCT
TTCCATCAATCAGACACGCCGGAAAAAGGACAAGCAATCGCCCGCAAGCTTCTGCAAAAGGCGGGGATTCCCCCGCACAT
GATAGAGAAAGCGTACGAAAACATTGCGGAATATGCAGAAGCAAGAGGAGCGGTCCTGTTTGATATCCGGGCAGGAGAAC
GCATTGACGGCAGAGGAAATAGAGGTGTGCGGGTATCCCGAATGGATTGGCCGTCACATGATTTTCAAAAATGGGCTTTT
ACGCACAACATGCCGGAAAATTCACGAATAAAAGAAGCACATGCCATCGCGGCAAAAGTTTGCGCACATCCGGGGATTAT
TGCTGAATTGTGCTGGTCGGATGACCCTGATTACATAACAGGCTACGTTGCCGCAAAGAAGCTGGGATATCAGCGGATTG
CCAAGATGAAGAATGCCGGAGATGAAAGCGGATGCCGGATTTTCTTTACAGATGGCTCCATAGATACGGAGAGTTGTATC
CATTTTTTGGAGAAGCAACCTGTATTCATTCAGCGGGAGGAGAACATATGA

Upstream 100 bases:

>100_bases
GACATATTCCGAGAAGGGCACTAATATTCTGTATAAGTGTTAACCTAAAATTTATTTTGGTTAACATTAATTTTCAAAGT
AAGAGAAAGGAGGGGAATAT

Downstream 100 bases:

>100_bases
AACAATCAATGATTGAAAAAAGCAAACAGCATCTTTGGCTGCCTTTCACACAAATGAAAGATTACGATGAAGATCCGTTA
ATCATTGAAAGCGGAAATGG

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFMQIQLESINEPIETIRPLPVA
FHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAEARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAF
THNMPENSRIKEAHAIAAKVCAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCI
HFLEKQPVFIQREENI

Sequences:

>Translated_256_residues
MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFMQIQLESINEPIETIRPLPVA
FHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAEARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAF
THNMPENSRIKEAHAIAAKVCAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCI
HFLEKQPVFIQREENI
>Mature_256_residues
MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFMQIQLESINEPIETIRPLPVA
FHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAEARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAF
THNMPENSRIKEAHAIAAKVCAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCI
HFLEKQPVFIQREENI

Specific function: Transforms pimelate into pimeloyl-CoA [H]

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005499
- ProDom:   PD017229 [H]

Pfam domain/function: PF03744 BioW [H]

EC number: =6.2.1.14 [H]

Molecular weight: Translated: 28862; Mature: 28862

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFM
CCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHH
QIQLESINEPIETIRPLPVAFHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAE
HHHHHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAFTHNMPENSRIKEAHAIAAKV
HCCCEEEEECCCCEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
CAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCI
HCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHH
HFLEKQPVFIQREENI
HHHHCCCEEEEECCCC
>Mature Secondary Structure
MREETYYSVRMRASRNAPHEQGGKHISGGERLITYSGLQEAVDGLLHKGFSHSRGIPDFM
CCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHH
QIQLESINEPIETIRPLPVAFHQSDTPEKGQAIARKLLQKAGIPPHMIEKAYENIAEYAE
HHHHHHHCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARGAVLFDIRAGERIDGRGNRGVRVSRMDWPSHDFQKWAFTHNMPENSRIKEAHAIAAKV
HCCCEEEEECCCCEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
CAHPGIIAELCWSDDPDYITGYVAAKKLGYQRIAKMKNAGDESGCRIFFTDGSIDTESCI
HCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHH
HFLEKQPVFIQREENI
HHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]