Click here to switch to the map view.

The map label for this gene is scoA [H]

Identifier: 154686255

GI number: 154686255

Start: 1910460

End: 1911161

Strand: Reverse

Name: scoA [H]

Synonym: RBAM_018220

Alternate gene names: 154686255

Gene position: 1911161-1910460 (Counterclockwise)

Preceding gene: 154686256

Following gene: 154686254

Centisome position: 48.77

GC content: 52.28

Gene sequence:

>702_bases
ATGGGAAAAGGAAAAGTGATGGACTCTTATCAAGATGCTGCTGCACTGATCAAGGACGGAGACACCCTCATCGCAGGAGG
CTTCGGCCTGTGCGGCATTCCGGAACAATTAATTCTCGCGATCAGGGACAGCGGCGTAAAAAACTTGACCGTTGTCAGTA
ATAACTGCGGTGTTGATGATTGGGGGTTAGGCCTCTTGCTTGCAAACCGGCAGATCAAAAAAATGGTCGCATCCTATGTG
GGAGAAAACAAAACCTTTGAACGGCAGTTTTTAAGCGGGGAGCTGGAAGTCGAATTGGTGCCCCAAGGAACGCTCGCAGA
AAGAATTCGCGCGGGAGGGGCGGGCATTCCGGCGTTTTACACACCTGCGGGCGTCGGAACATCAGTAGCCGAGGGAAAAG
AACATAAGACATTTGACGGACGCACCTATCTTCTGGAGAAAGGGATTACAGGGAACGCCGCCATCGTAAAGGCCTGGAAA
GCCGATCCTCTGGGCAACCTGATGTTCAGAAAGACGGCGAGAAATTTCAATCCGCTCGCTGCAATGGCAGGCAAAGTGAC
GATTGCAGAGGCTGAAGAAATCGTCGATGCCGGAGAGCTTGATCCGGATCAAATTCATACGCCGGGTATTTTTGTGCAGC
ACGTGCTGCTCGGCGGGATTCATGAAAAACGGATTGAACGCCGCACCGTCCGGCAAGCATGA

Upstream 100 bases:

>100_bases
CTTTGCCATTACCGTCATTAAAACAGCCGCTGTGTTTGTCATCATCGCCATTTACAGTCTGACGGGCCTTGTGTAGCCAA
AACAGAAAGGGGAAACGAAT

Downstream 100 bases:

>100_bases
TAAAGGAGGCTGACAGAATGAGAGATAGCAGAAAACGAATGATCAAACGGGCTGTAAAGGAAATTAAGGACGGAATGAAT
GTGAACTTGGGGATAGGGAT

Product: ScoA

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MGKGKVMDSYQDAAALIKDGDTLIAGGFGLCGIPEQLILAIRDSGVKNLTVVSNNCGVDDWGLGLLLANRQIKKMVASYV
GENKTFERQFLSGELEVELVPQGTLAERIRAGGAGIPAFYTPAGVGTSVAEGKEHKTFDGRTYLLEKGITGNAAIVKAWK
ADPLGNLMFRKTARNFNPLAAMAGKVTIAEAEEIVDAGELDPDQIHTPGIFVQHVLLGGIHEKRIERRTVRQA

Sequences:

>Translated_233_residues
MGKGKVMDSYQDAAALIKDGDTLIAGGFGLCGIPEQLILAIRDSGVKNLTVVSNNCGVDDWGLGLLLANRQIKKMVASYV
GENKTFERQFLSGELEVELVPQGTLAERIRAGGAGIPAFYTPAGVGTSVAEGKEHKTFDGRTYLLEKGITGNAAIVKAWK
ADPLGNLMFRKTARNFNPLAAMAGKVTIAEAEEIVDAGELDPDQIHTPGIFVQHVLLGGIHEKRIERRTVRQA
>Mature_232_residues
GKGKVMDSYQDAAALIKDGDTLIAGGFGLCGIPEQLILAIRDSGVKNLTVVSNNCGVDDWGLGLLLANRQIKKMVASYVG
ENKTFERQFLSGELEVELVPQGTLAERIRAGGAGIPAFYTPAGVGTSVAEGKEHKTFDGRTYLLEKGITGNAAIVKAWKA
DPLGNLMFRKTARNFNPLAAMAGKVTIAEAEEIVDAGELDPDQIHTPGIFVQHVLLGGIHEKRIERRTVRQA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=239, Percent_Identity=56.9037656903766, Blast_Score=270, Evalue=6e-73,
Organism=Homo sapiens, GI11545841, Length=242, Percent_Identity=52.8925619834711, Blast_Score=236, Evalue=9e-63,
Organism=Escherichia coli, GI1788551, Length=215, Percent_Identity=46.046511627907, Blast_Score=210, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17531517, Length=245, Percent_Identity=53.0612244897959, Blast_Score=259, Evalue=9e-70,
Organism=Drosophila melanogaster, GI21358325, Length=247, Percent_Identity=51.8218623481781, Blast_Score=257, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24655794, Length=247, Percent_Identity=51.8218623481781, Blast_Score=256, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24958; Mature: 24827

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGKVMDSYQDAAALIKDGDTLIAGGFGLCGIPEQLILAIRDSGVKNLTVVSNNCGVDD
CCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
WGLGLLLANRQIKKMVASYVGENKTFERQFLSGELEVELVPQGTLAERIRAGGAGIPAFY
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEE
TPAGVGTSVAEGKEHKTFDGRTYLLEKGITGNAAIVKAWKADPLGNLMFRKTARNFNPLA
CCCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHH
AMAGKVTIAEAEEIVDAGELDPDQIHTPGIFVQHVLLGGIHEKRIERRTVRQA
HHHCCEEEHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKGKVMDSYQDAAALIKDGDTLIAGGFGLCGIPEQLILAIRDSGVKNLTVVSNNCGVDD
CCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
WGLGLLLANRQIKKMVASYVGENKTFERQFLSGELEVELVPQGTLAERIRAGGAGIPAFY
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEE
TPAGVGTSVAEGKEHKTFDGRTYLLEKGITGNAAIVKAWKADPLGNLMFRKTARNFNPLA
CCCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHH
AMAGKVTIAEAEEIVDAGELDPDQIHTPGIFVQHVLLGGIHEKRIERRTVRQA
HHHCCEEEHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]