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The map label for this gene is scoB [H]

Identifier: 154686254

GI number: 154686254

Start: 1909780

End: 1910442

Strand: Reverse

Name: scoB [H]

Synonym: RBAM_018210

Alternate gene names: 154686254

Gene position: 1910442-1909780 (Counterclockwise)

Preceding gene: 154686255

Following gene: 154686253

Centisome position: 48.75

GC content: 48.72

Gene sequence:

>663_bases
ATGAGAGATAGCAGAAAACGAATGATCAAACGGGCTGTAAAGGAAATTAAGGACGGAATGAATGTGAACTTGGGGATAGG
GATGCCGACGCTTGTAGCCAATGAGATACCGAATGATTATAACGTCCTGCTTCAGTCTGAAAACGGCTTGCTCGGGATCG
GGCCTTATCCGGCGGAAGGAACGGAGGACCCCGATCTGATCAACGCGGGAAAAGAAACCATCACCGAAGTAAAGGGAGCC
TCGTATTTTGACAGTGCCGAATCCTTTGCCATGATTCGCGGCGGCCACATTGATGTAGCGATCCTCGGCGGGATGGAAGT
GTCCGAACGGGGAGATTTGGCGAACTGGATGATCCCCGGAAAAATGATCAAAGGAATGGGCGGCGCAATGGACCTAGTTC
ACGGAGCAAAACGGATTATTGTCATTATGGAGCACGTTAATAAATATGGGGAATCTAAAGTGAGAACGGAATGTACGCTG
CCTTTAACCGGCAGGCAGGTGGTCGATCGGCTGATCACAGATTTGGCTGTATTCGATTTTCATGATGGCCGTATGACGCT
CACCGAACTGCAGGAAGGTGTAACAATGGAGGAGGTCTTTGAGAAAACAGAAGGTCATTTTACTGTCAGCCAGTCGTTAA
AAAACGGGATCAGACCAAAATGA

Upstream 100 bases:

>100_bases
CGCCGGGTATTTTTGTGCAGCACGTGCTGCTCGGCGGGATTCATGAAAAACGGATTGAACGCCGCACCGTCCGGCAAGCA
TGATAAAGGAGGCTGACAGA

Downstream 100 bases:

>100_bases
GGAGGTGCCGTCATGCATTCATTGCTTATTGAAAAAACAGCCGTTGTAACAGGTGCAGCAGGAGGAATCGGGCTCGAAAT
CGCAAAAGAATTCGCCCGTG

Product: ScoB

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRDSRKRMIKRAVKEIKDGMNVNLGIGMPTLVANEIPNDYNVLLQSENGLLGIGPYPAEGTEDPDLINAGKETITEVKGA
SYFDSAESFAMIRGGHIDVAILGGMEVSERGDLANWMIPGKMIKGMGGAMDLVHGAKRIIVIMEHVNKYGESKVRTECTL
PLTGRQVVDRLITDLAVFDFHDGRMTLTELQEGVTMEEVFEKTEGHFTVSQSLKNGIRPK

Sequences:

>Translated_220_residues
MRDSRKRMIKRAVKEIKDGMNVNLGIGMPTLVANEIPNDYNVLLQSENGLLGIGPYPAEGTEDPDLINAGKETITEVKGA
SYFDSAESFAMIRGGHIDVAILGGMEVSERGDLANWMIPGKMIKGMGGAMDLVHGAKRIIVIMEHVNKYGESKVRTECTL
PLTGRQVVDRLITDLAVFDFHDGRMTLTELQEGVTMEEVFEKTEGHFTVSQSLKNGIRPK
>Mature_220_residues
MRDSRKRMIKRAVKEIKDGMNVNLGIGMPTLVANEIPNDYNVLLQSENGLLGIGPYPAEGTEDPDLINAGKETITEVKGA
SYFDSAESFAMIRGGHIDVAILGGMEVSERGDLANWMIPGKMIKGMGGAMDLVHGAKRIIVIMEHVNKYGESKVRTECTL
PLTGRQVVDRLITDLAVFDFHDGRMTLTELQEGVTMEEVFEKTEGHFTVSQSLKNGIRPK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=213, Percent_Identity=58.2159624413146, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI11545841, Length=214, Percent_Identity=53.7383177570093, Blast_Score=235, Evalue=3e-62,
Organism=Escherichia coli, GI1788552, Length=213, Percent_Identity=50.7042253521127, Blast_Score=232, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17531517, Length=213, Percent_Identity=56.3380281690141, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI21358325, Length=212, Percent_Identity=55.6603773584906, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24655794, Length=212, Percent_Identity=55.6603773584906, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24193; Mature: 24193

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSRKRMIKRAVKEIKDGMNVNLGIGMPTLVANEIPNDYNVLLQSENGLLGIGPYPAEG
CCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC
TEDPDLINAGKETITEVKGASYFDSAESFAMIRGGHIDVAILGGMEVSERGDLANWMIPG
CCCCHHHHCCHHHHHHHCCCCHHCCHHHHHEEECCCEEEEEECCCEECCCCCCCHHCCCH
KMIKGMGGAMDLVHGAKRIIVIMEHVNKYGESKVRTECTLPLTGRQVVDRLITDLAVFDF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEECCCCCHHHHHHHHHHHHHHEEC
HDGRMTLTELQEGVTMEEVFEKTEGHFTVSQSLKNGIRPK
CCCCEEHHHHHHCCCHHHHHHHHCCCEEEHHHHHCCCCCC
>Mature Secondary Structure
MRDSRKRMIKRAVKEIKDGMNVNLGIGMPTLVANEIPNDYNVLLQSENGLLGIGPYPAEG
CCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC
TEDPDLINAGKETITEVKGASYFDSAESFAMIRGGHIDVAILGGMEVSERGDLANWMIPG
CCCCHHHHCCHHHHHHHCCCCHHCCHHHHHEEECCCEEEEEECCCEECCCCCCCHHCCCH
KMIKGMGGAMDLVHGAKRIIVIMEHVNKYGESKVRTECTLPLTGRQVVDRLITDLAVFDF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEECCCCCHHHHHHHHHHHHHHEEC
HDGRMTLTELQEGVTMEEVFEKTEGHFTVSQSLKNGIRPK
CCCCEEHHHHHHCCCHHHHHHHHCCCEEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]