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The map label for this gene is bmyD [H]

Identifier: 154686252

GI number: 154686252

Start: 1907220

End: 1908422

Strand: Reverse

Name: bmyD [H]

Synonym: RBAM_018190

Alternate gene names: 154686252

Gene position: 1908422-1907220 (Counterclockwise)

Preceding gene: 154686253

Following gene: 154686251

Centisome position: 48.7

GC content: 44.97

Gene sequence:

>1203_bases
ATGAACAATCTTGCCTTTTTATTTCCTGGACAAGGGTCTCAATTTGTAGGAATGGGCAAACAATTTTGGAATGATTTTGT
GCTCGCAAAGAGATTGTTTGAAGAAGCGAGCGATGCGATCTCCTTGGATGTAAAAAAACTGTGTTTTAACGGAGATATGA
ATGAATTGACAAAGACAATGAACGCGCAGCCCGCTATTTTAACGGTCAGTGTGATTGCTTTTCAAGTGTATATGCAGGAA
ATAGGGGTGAAGCCCCGCTTCCTGGCAGGCCATAGCTTAGGCGAATATTCAGCGCTTGTCTGTGCCGGCGCCCTTTCTTT
TCGGGATGCCGTTACACTTGTAAGGGAGCGGGGAATTCTTATGCAAAATGCAGATCCCCAGCAGCAGGGGGCGATGGCCG
CCGTGACTCACCTCTCTCTTCAAACGTTGCAGGAAATATGTTCGAAAATATCGACGGAAGACTTTCCGGCAGGTGTAGCC
TGCATGAATTCAGAACAGCAGCATGTGATTTCCGGACACCGGCAAGCTGTGGAACGTGTCATCAAGATGGCGGAGGAAAA
GGGTGCGGCATACACTTATTTGAATGTCAGTGCGCCTTTTCACAGTTCGATGATACGATCAGCCTCCGAACAATTCCAGA
CTGTATTACACCAGTATTCTTTCCGGGATGCCGCATGGCCGATTATTTCAAATGTCACCGCGCGCCCTTACAGCAGCGGA
AATTCGATCAGCGAACATCTCAAGCAGCACATGACGATGCCGGTTAGATGGACAGAATCGATGCATTACTTGCTTTTACA
TGGAGTCACAGAAGTCATCGAAATGGGTCCGAACAATGTCTTAGCCGGTCTGCTGAGAAAAACAACGAATCACATTGTAC
CTTATCCCTTAGGACAGACATCTGATGTTCCCCCGCTTTCCAATTCAGCGGAAAGAAAGAAACATATTGTCCATTTACGC
AAAAAACAACTGAATAAATTGATGATTCAATCCGTCATAGCGCGAAATTACAACAAGGATTCAGCGGCTTATTCCAATAT
GACGACGCCATTATTTACGCAAATCCAAGAGCTGAAAGAGAGAATGAAAAGGCATGAAGACGTGCTTTCAGAACAAGAAC
TCGAACATTCGATCCATTTATGCAAATTAATTTGTGAAGCTAAACAGCTTCCGGCTTGGGAAGAATTGCGGATTTTAAAA
TAA

Upstream 100 bases:

>100_bases
AGTATTCTATACACATTTGTTATAATCATGCTAGGATGTTAGATAAAGGGATATTTTGTAGGATATTGTATCCCCTGTTC
AATATGATCGGAGGAATCTC

Downstream 100 bases:

>100_bases
AGCGCCCAGGAGGGGACCTATGTATACCAGTCAATTCCAAACCTTAGTAGACGTCATTCGGGAAAGAAGCAATATCTCTG
ATCGCGGGATCCGTTTTATC

Product: BmyD

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNNLAFLFPGQGSQFVGMGKQFWNDFVLAKRLFEEASDAISLDVKKLCFNGDMNELTKTMNAQPAILTVSVIAFQVYMQE
IGVKPRFLAGHSLGEYSALVCAGALSFRDAVTLVRERGILMQNADPQQQGAMAAVTHLSLQTLQEICSKISTEDFPAGVA
CMNSEQQHVISGHRQAVERVIKMAEEKGAAYTYLNVSAPFHSSMIRSASEQFQTVLHQYSFRDAAWPIISNVTARPYSSG
NSISEHLKQHMTMPVRWTESMHYLLLHGVTEVIEMGPNNVLAGLLRKTTNHIVPYPLGQTSDVPPLSNSAERKKHIVHLR
KKQLNKLMIQSVIARNYNKDSAAYSNMTTPLFTQIQELKERMKRHEDVLSEQELEHSIHLCKLICEAKQLPAWEELRILK

Sequences:

>Translated_400_residues
MNNLAFLFPGQGSQFVGMGKQFWNDFVLAKRLFEEASDAISLDVKKLCFNGDMNELTKTMNAQPAILTVSVIAFQVYMQE
IGVKPRFLAGHSLGEYSALVCAGALSFRDAVTLVRERGILMQNADPQQQGAMAAVTHLSLQTLQEICSKISTEDFPAGVA
CMNSEQQHVISGHRQAVERVIKMAEEKGAAYTYLNVSAPFHSSMIRSASEQFQTVLHQYSFRDAAWPIISNVTARPYSSG
NSISEHLKQHMTMPVRWTESMHYLLLHGVTEVIEMGPNNVLAGLLRKTTNHIVPYPLGQTSDVPPLSNSAERKKHIVHLR
KKQLNKLMIQSVIARNYNKDSAAYSNMTTPLFTQIQELKERMKRHEDVLSEQELEHSIHLCKLICEAKQLPAWEELRILK
>Mature_400_residues
MNNLAFLFPGQGSQFVGMGKQFWNDFVLAKRLFEEASDAISLDVKKLCFNGDMNELTKTMNAQPAILTVSVIAFQVYMQE
IGVKPRFLAGHSLGEYSALVCAGALSFRDAVTLVRERGILMQNADPQQQGAMAAVTHLSLQTLQEICSKISTEDFPAGVA
CMNSEQQHVISGHRQAVERVIKMAEEKGAAYTYLNVSAPFHSSMIRSASEQFQTVLHQYSFRDAAWPIISNVTARPYSSG
NSISEHLKQHMTMPVRWTESMHYLLLHGVTEVIEMGPNNVLAGLLRKTTNHIVPYPLGQTSDVPPLSNSAERKKHIVHLR
KKQLNKLMIQSVIARNYNKDSAAYSNMTTPLFTQIQELKERMKRHEDVLSEQELEHSIHLCKLICEAKQLPAWEELRILK

Specific function: Is involved in the mycosubtilin synthetase assembly, by catalyzing the transfer of malonyl groups to a specific acyl- carrier-protein domain on mycA [H]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=28.4280936454849, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41872631, Length=312, Percent_Identity=26.6025641025641, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27477045, Length=117, Percent_Identity=35.042735042735, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787334, Length=302, Percent_Identity=38.0794701986755, Blast_Score=204, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI71984332, Length=279, Percent_Identity=29.3906810035842, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=293, Percent_Identity=28.3276450511945, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=25.3246753246753, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=32.6666666666667, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 44983; Mature: 44983

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLAFLFPGQGSQFVGMGKQFWNDFVLAKRLFEEASDAISLDVKKLCFNGDMNELTKTM
CCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NAQPAILTVSVIAFQVYMQEIGVKPRFLAGHSLGEYSALVCAGALSFRDAVTLVRERGIL
CCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
MQNADPQQQGAMAAVTHLSLQTLQEICSKISTEDFPAGVACMNSEQQHVISGHRQAVERV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
IKMAEEKGAAYTYLNVSAPFHSSMIRSASEQFQTVLHQYSFRDAAWPIISNVTARPYSSG
HHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
NSISEHLKQHMTMPVRWTESMHYLLLHGVTEVIEMGPNNVLAGLLRKTTNHIVPYPLGQT
CHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
SDVPPLSNSAERKKHIVHLRKKQLNKLMIQSVIARNYNKDSAAYSNMTTPLFTQIQELKE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHH
RMKRHEDVLSEQELEHSIHLCKLICEAKQLPAWEELRILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MNNLAFLFPGQGSQFVGMGKQFWNDFVLAKRLFEEASDAISLDVKKLCFNGDMNELTKTM
CCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NAQPAILTVSVIAFQVYMQEIGVKPRFLAGHSLGEYSALVCAGALSFRDAVTLVRERGIL
CCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
MQNADPQQQGAMAAVTHLSLQTLQEICSKISTEDFPAGVACMNSEQQHVISGHRQAVERV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
IKMAEEKGAAYTYLNVSAPFHSSMIRSASEQFQTVLHQYSFRDAAWPIISNVTARPYSSG
HHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
NSISEHLKQHMTMPVRWTESMHYLLLHGVTEVIEMGPNNVLAGLLRKTTNHIVPYPLGQT
CHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
SDVPPLSNSAERKKHIVHLRKKQLNKLMIQSVIARNYNKDSAAYSNMTTPLFTQIQELKE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHH
RMKRHEDVLSEQELEHSIHLCKLICEAKQLPAWEELRILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10557314 [H]