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The map label for this gene is speA [H]

Identifier: 154685882

GI number: 154685882

Start: 1452282

End: 1453754

Strand: Reverse

Name: speA [H]

Synonym: RBAM_014490

Alternate gene names: 154685882

Gene position: 1453754-1452282 (Counterclockwise)

Preceding gene: 154685884

Following gene: 154685879

Centisome position: 37.1

GC content: 48.68

Gene sequence:

>1473_bases
TTGCCGCAACATGAAACACCCCTGTACAGCGGACTGAAAAAGCACGCGGACAGACAGCCTGTCCAATTCCACATTCCGGG
CCATAAAAAAGGCGCGGGAATGGATCCGGAATTCAGACAATTTATCGGAGAAAACGCGTTAAGCATAGATTTAATTAATA
TCGAACCCCTGGATGATTTACATGCGCCAAAGGGCATCATTAAAGAAGCCCAGGATCTGGCCGCTCGAGCATTCGGTGCA
GACCATACCTTCTTTTCCGTACAAGGGACGAGCGGCGCCATTATGACGATGGTCATGGCTGTATGCGGACCCGGAGATAA
AATCATCATCCCGAGAAACGTTCATAAATCCATTATGTCGGCCATTGTATTTTCCGGAGCGGTGCCGATTTTTATTCACC
CGGAAATTGACGATGAGCTCGGAATTTCTCACGGCATTACGCTTGAGTCCGCCGAGCGGGCTTTGACGGAGCACCCTGAC
GCAAAAGGCCTGCTTGTCATAAATCCGACGTACTTCGGTGTGGCAGCTGACTTGAGCAGCATTGTAAAGCTCGCGCATTC
TTTCGATGTGCCTGTGCTTGTCGATGAAGCGCACGGCGTGCATATTCATTTTCATGATAAGCTTCCTCTGTCCGCCATGC
AGGCGGGCGCTGATATGGCAGCTACTAGCGTGCACAAATTGGGAGGCTCCCTGACGCAGAGCTCCATTTTAAATGTGAGA
GAAGGTCTTGTTTCCAAAGAAAGAGTACAGTCGATTTTAAGCATGCTGACGACAACGTCAACATCCTATCTGCTTCTCGC
TTCACTTGATGTCGCAAGAAAACGCCTCGCTACAGAAGGCCGAGATCTTCTTGAAGATACGATTCTGCTGGCGGATCAGA
CACGGGAACGCCTCAATCAAATTGAAGGCATCCGCTGTGTCGGCGAAGAAATCACAGGGTCTAAAGCTGCCTTCAGTTAT
GATCCGACTAAATTAATCATTTCGGTCAAAAACCTCGGCCTGACGGGTCATGACGTTGAAAAATGGCTCCGCGAATCATA
TAATATCGAAGTCGAGCTGTCCGATTTGTATAATATTTTATGTATTTTCACCCCCGGCGACAGAGCGGGAGATGCCGACC
GTCTTGTAAGCGCGCTTACAGACATTTCAAAGCAGGCTTCCGACAACGACTATGCTCATCAGCAAACCGAAGTTCTGCTT
CCTGAGATTCCTCTGTTAGCGATGACGCCAAGAGACGCGTTTTACGCAAATACGGAAGTCATTCCGTTAAAAGAATCCGC
GGGACGGATCATCGCAGAGTTTGTCATGGTGTACCCGCCGGGAATTCCGATCTTTATTCCGGGCGAGATCATTACTGAAG
AAAATATCAGCTACATTTTTAAAAACTTGGACGCCGGCCTTCCTGTGCAGGGTCCCGAAGATGCAACGCTTGAAATGATC
AGAGTCATCAAAGAGCAAAAAGCCATCCAATAA

Upstream 100 bases:

>100_bases
TCATAATATAATTCATTTGTTTTACGTTTAAAAAACGGGTAATAAAACTGAATGTAATACAAACTAATCCGTAGGTATTA
TGATAAAGGTGGGAAAACAA

Downstream 100 bases:

>100_bases
ACATAAAGAAGCCCGAAACGAAATCGTTTCGGGCCTTTTTACGCTTTTTACTCTTCTTCAAGATGACACTGGCATTGTCC
GCAGCATGTTCCGTATAACG

Product: SpeA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPQHETPLYSGLKKHADRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDLHAPKGIIKEAQDLAARAFGA
DHTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMSAIVFSGAVPIFIHPEIDDELGISHGITLESAERALTEHPD
AKGLLVINPTYFGVAADLSSIVKLAHSFDVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
EGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGRDLLEDTILLADQTRERLNQIEGIRCVGEEITGSKAAFSY
DPTKLIISVKNLGLTGHDVEKWLRESYNIEVELSDLYNILCIFTPGDRAGDADRLVSALTDISKQASDNDYAHQQTEVLL
PEIPLLAMTPRDAFYANTEVIPLKESAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDATLEMI
RVIKEQKAIQ

Sequences:

>Translated_490_residues
MPQHETPLYSGLKKHADRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDLHAPKGIIKEAQDLAARAFGA
DHTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMSAIVFSGAVPIFIHPEIDDELGISHGITLESAERALTEHPD
AKGLLVINPTYFGVAADLSSIVKLAHSFDVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
EGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGRDLLEDTILLADQTRERLNQIEGIRCVGEEITGSKAAFSY
DPTKLIISVKNLGLTGHDVEKWLRESYNIEVELSDLYNILCIFTPGDRAGDADRLVSALTDISKQASDNDYAHQQTEVLL
PEIPLLAMTPRDAFYANTEVIPLKESAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDATLEMI
RVIKEQKAIQ
>Mature_489_residues
PQHETPLYSGLKKHADRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDLHAPKGIIKEAQDLAARAFGAD
HTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMSAIVFSGAVPIFIHPEIDDELGISHGITLESAERALTEHPDA
KGLLVINPTYFGVAADLSSIVKLAHSFDVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNVRE
GLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGRDLLEDTILLADQTRERLNQIEGIRCVGEEITGSKAAFSYD
PTKLIISVKNLGLTGHDVEKWLRESYNIEVELSDLYNILCIFTPGDRAGDADRLVSALTDISKQASDNDYAHQQTEVLLP
EIPLLAMTPRDAFYANTEVIPLKESAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDATLEMIR
VIKEQKAIQ

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=546, Percent_Identity=26.7399267399267, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786384, Length=545, Percent_Identity=25.6880733944954, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI221142684, Length=380, Percent_Identity=27.3684210526316, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786909, Length=597, Percent_Identity=24.1206030150754, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082193, Length=566, Percent_Identity=23.321554770318, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53483; Mature: 53352

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQHETPLYSGLKKHADRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDL
CCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCHHH
HAPKGIIKEAQDLAARAFGADHTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMS
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHH
AIVFSGAVPIFIHPEIDDELGISHGITLESAERALTEHPDAKGLLVINPTYFGVAADLSS
HHHHCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
IVKLAHSFDVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
HHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
EGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGRDLLEDTILLADQTRERLNQ
HHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEGIRCVGEEITGSKAAFSYDPTKLIISVKNLGLTGHDVEKWLRESYNIEVELSDLYNIL
HCCCEEECCCCCCCCCEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCEEEE
CIFTPGDRAGDADRLVSALTDISKQASDNDYAHQQTEVLLPEIPLLAMTPRDAFYANTEV
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCHHCCCCEE
IPLKESAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDATLEMI
EECHHHHHHHHHHHHHHCCCCCCEEECCCEECCCHHHHHHHHCCCCCCCCCCCHHHHHHH
RVIKEQKAIQ
HHHHHHHCCC
>Mature Secondary Structure 
PQHETPLYSGLKKHADRQPVQFHIPGHKKGAGMDPEFRQFIGENALSIDLINIEPLDDL
CCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCHHH
HAPKGIIKEAQDLAARAFGADHTFFSVQGTSGAIMTMVMAVCGPGDKIIIPRNVHKSIMS
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHHHHH
AIVFSGAVPIFIHPEIDDELGISHGITLESAERALTEHPDAKGLLVINPTYFGVAADLSS
HHHHCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
IVKLAHSFDVPVLVDEAHGVHIHFHDKLPLSAMQAGADMAATSVHKLGGSLTQSSILNVR
HHHHHHHCCCCEEEECCCEEEEEEECCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHH
EGLVSKERVQSILSMLTTTSTSYLLLASLDVARKRLATEGRDLLEDTILLADQTRERLNQ
HHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEGIRCVGEEITGSKAAFSYDPTKLIISVKNLGLTGHDVEKWLRESYNIEVELSDLYNIL
HCCCEEECCCCCCCCCEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCEEEE
CIFTPGDRAGDADRLVSALTDISKQASDNDYAHQQTEVLLPEIPLLAMTPRDAFYANTEV
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCHHCCCCEE
IPLKESAGRIIAEFVMVYPPGIPIFIPGEIITEENISYIFKNLDAGLPVQGPEDATLEMI
EECHHHHHHHHHHHHHHCCCCCCEEECCCEECCCHHHHHHHHCCCCCCCCCCCHHHHHHH
RVIKEQKAIQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]