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The map label for this gene is patA [H]

Identifier: 154685811

GI number: 154685811

Start: 1342400

End: 1343560

Strand: Reverse

Name: patA [H]

Synonym: RBAM_013780

Alternate gene names: 154685811

Gene position: 1343560-1342400 (Counterclockwise)

Preceding gene: 154685812

Following gene: 154685808

Centisome position: 34.29

GC content: 46.43

Gene sequence:

>1161_bases
TTGCTTAATCCGAATGTAAAAGAAATTGAAATTTCAGGAATTCGCAAATTCTCAAATCTTGTAGCTCAGCACGACAATGT
CATTTCGCTTACGATCGGTCAGCCGGATTTCTTCACGCCGCACCATGTCAAAGCGGCTGCCAAAAAGGCAATCGACGAGA
ACGCAACGGCATATACTCCGAATGCGGGCGGCCTTGAGCTGAGACAGGCCGTACAGCTTTATATGAAGAAAAAAGCTGAT
TTGAATTATGAAGCTGAAACTGAAATCATCGTCACAACCGGGGCAAGCCAAGCGATTGACGCGTCTTTGCGGACGATTTT
ATCTCCGGGCGATGAAGTTATTCTCCCCGGACCGATATATCCGGGCTACGAACCGATCATCCGCATGTCGGGTGCCGTTC
CGGTCCATGTGGATACGACGACACACGGATTTAAGCTGACGGCGCGGCTCATTGAAGAATCGCTGACACCAAAAACAAAA
TGCGTCATTCTTCCTTATCCGTCAAACCCGACCGGAGTGACATTGTCTGAGGAAGAGCTGCAAAACATCGCAGCCGTCCT
GAAGGGCAGAAATGTTTTTGTCCTGTCTGATGAGATTTACAGCGAATTAACCTATGACAGACCGCATTATTCGATCGCGT
CTTATTTGAGAGACCAGACGATCGTCATCAACGGCCTGTCAAAATCACACAGCATGACGGGCTGGAGAATCGGTTTCATT
TTCGCACCGAAAGAAATTGCCAAGCACATCTTAAAAGTTCACCAATACAGTGTGACATGCGCGTCTTCAATCTCTCAGAA
AGCGGCTCTTGAAGCGGTGACAAACGGTGTTGATGATGCGCTTATTATGAGAGAACAGTATAAAAAGCGGCTTGACTATG
TATATGACCGTCTTGTTTCAATGGGGCTTGACGTCGTAAAGCCGTCAGGCGCATTTTATATCTTCCCTTCCATTAAGTCA
TTCGGAATGTCATCGTTTGATTTTAGTATGGCTCTTTTAGAGGATGCAGGTGTGGCTCTTGTGCCCGGCAGCTCGTTTTC
AAAGTTGGGTGAAGGGTATGTGAGGCTGTCATTCGCATATTCACTGAATACATTGAGAGAAGGCTTGGACCGGCTGGAAG
CATTTATTTTAAAAACGAGAGAATCCATGCAGACTATTTAA

Upstream 100 bases:

>100_bases
ATATACTCGGGATAGTTCAATAAAAAGATGACAAATGCTCAGCTAGTGGTAAAATAGGAGAAACTCAATATATAGTATAA
GGTGATGAATTATGGAACAT

Downstream 100 bases:

>100_bases
ACAACGGCATAACGCCGTTGTTTTTTATTGTTTCGGGAATGTAATATGAAAGGCCGTGCCTCTATCCGGTTTGCTGTCTA
CTTGGATAGCTCCCTGGTGG

Product: aminotransferase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MLNPNVKEIEISGIRKFSNLVAQHDNVISLTIGQPDFFTPHHVKAAAKKAIDENATAYTPNAGGLELRQAVQLYMKKKAD
LNYEAETEIIVTTGASQAIDASLRTILSPGDEVILPGPIYPGYEPIIRMSGAVPVHVDTTTHGFKLTARLIEESLTPKTK
CVILPYPSNPTGVTLSEEELQNIAAVLKGRNVFVLSDEIYSELTYDRPHYSIASYLRDQTIVINGLSKSHSMTGWRIGFI
FAPKEIAKHILKVHQYSVTCASSISQKAALEAVTNGVDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPSIKS
FGMSSFDFSMALLEDAGVALVPGSSFSKLGEGYVRLSFAYSLNTLREGLDRLEAFILKTRESMQTI

Sequences:

>Translated_386_residues
MLNPNVKEIEISGIRKFSNLVAQHDNVISLTIGQPDFFTPHHVKAAAKKAIDENATAYTPNAGGLELRQAVQLYMKKKAD
LNYEAETEIIVTTGASQAIDASLRTILSPGDEVILPGPIYPGYEPIIRMSGAVPVHVDTTTHGFKLTARLIEESLTPKTK
CVILPYPSNPTGVTLSEEELQNIAAVLKGRNVFVLSDEIYSELTYDRPHYSIASYLRDQTIVINGLSKSHSMTGWRIGFI
FAPKEIAKHILKVHQYSVTCASSISQKAALEAVTNGVDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPSIKS
FGMSSFDFSMALLEDAGVALVPGSSFSKLGEGYVRLSFAYSLNTLREGLDRLEAFILKTRESMQTI
>Mature_386_residues
MLNPNVKEIEISGIRKFSNLVAQHDNVISLTIGQPDFFTPHHVKAAAKKAIDENATAYTPNAGGLELRQAVQLYMKKKAD
LNYEAETEIIVTTGASQAIDASLRTILSPGDEVILPGPIYPGYEPIIRMSGAVPVHVDTTTHGFKLTARLIEESLTPKTK
CVILPYPSNPTGVTLSEEELQNIAAVLKGRNVFVLSDEIYSELTYDRPHYSIASYLRDQTIVINGLSKSHSMTGWRIGFI
FAPKEIAKHILKVHQYSVTCASSISQKAALEAVTNGVDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPSIKS
FGMSSFDFSMALLEDAGVALVPGSSFSKLGEGYVRLSFAYSLNTLREGLDRLEAFILKTRESMQTI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=398, Percent_Identity=28.894472361809, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=398, Percent_Identity=28.894472361809, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=26.302729528536, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=26.302729528536, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881281, Length=304, Percent_Identity=26.6447368421053, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=27.6595744680851, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI149944424, Length=325, Percent_Identity=24.6153846153846, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI215599424, Length=397, Percent_Identity=24.1813602015113, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI19263340, Length=397, Percent_Identity=24.1813602015113, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI187936925, Length=358, Percent_Identity=22.9050279329609, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI14211921, Length=358, Percent_Identity=22.9050279329609, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1786816, Length=358, Percent_Identity=26.536312849162, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=29.2011019283747, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=26.2337662337662, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787710, Length=321, Percent_Identity=26.1682242990654, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787909, Length=278, Percent_Identity=23.3812949640288, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788332, Length=168, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790797, Length=403, Percent_Identity=21.3399503722084, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=393, Percent_Identity=23.4096692111959, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=196, Percent_Identity=30.1020408163265, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=196, Percent_Identity=30.1020408163265, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=407, Percent_Identity=25.5528255528256, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=384, Percent_Identity=23.9583333333333, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=26.1421319796954, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=352, Percent_Identity=24.7159090909091, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=26.8542199488491, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=26.8542199488491, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=26.8542199488491, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=26.8542199488491, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=26.6331658291457, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42565; Mature: 42565

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPNVKEIEISGIRKFSNLVAQHDNVISLTIGQPDFFTPHHVKAAAKKAIDENATAYTP
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEECC
NAGGLELRQAVQLYMKKKADLNYEAETEIIVTTGASQAIDASLRTILSPGDEVILPGPIY
CCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCC
PGYEPIIRMSGAVPVHVDTTTHGFKLTARLIEESLTPKTKCVILPYPSNPTGVTLSEEEL
CCCHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECHHHH
QNIAAVLKGRNVFVLSDEIYSELTYDRPHYSIASYLRDQTIVINGLSKSHSMTGWRIGFI
HHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEEEE
FAPKEIAKHILKVHQYSVTCASSISQKAALEAVTNGVDDALIMREQYKKRLDYVYDRLVS
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MGLDVVKPSGAFYIFPSIKSFGMSSFDFSMALLEDAGVALVPGSSFSKLGEGYVRLSFAY
CCCCEECCCCCEEEECCHHHCCCCCCCHHHHHHCCCCEEEECCCCHHHHCCCEEEEEEEH
SLNTLREGLDRLEAFILKTRESMQTI
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNPNVKEIEISGIRKFSNLVAQHDNVISLTIGQPDFFTPHHVKAAAKKAIDENATAYTP
CCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEECC
NAGGLELRQAVQLYMKKKADLNYEAETEIIVTTGASQAIDASLRTILSPGDEVILPGPIY
CCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCC
PGYEPIIRMSGAVPVHVDTTTHGFKLTARLIEESLTPKTKCVILPYPSNPTGVTLSEEEL
CCCHHHHEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECHHHH
QNIAAVLKGRNVFVLSDEIYSELTYDRPHYSIASYLRDQTIVINGLSKSHSMTGWRIGFI
HHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEEEEE
FAPKEIAKHILKVHQYSVTCASSISQKAALEAVTNGVDDALIMREQYKKRLDYVYDRLVS
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
MGLDVVKPSGAFYIFPSIKSFGMSSFDFSMALLEDAGVALVPGSSFSKLGEGYVRLSFAY
CCCCEECCCCCEEEECCHHHCCCCCCCHHHHHHCCCCEEEECCCCHHHHCCCEEEEEEEH
SLNTLREGLDRLEAFILKTRESMQTI
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]