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The map label for this gene is trpS [H]

Identifier: 154685576

GI number: 154685576

Start: 1118918

End: 1119910

Strand: Reverse

Name: trpS [H]

Synonym: RBAM_011420

Alternate gene names: 154685576

Gene position: 1119910-1118918 (Counterclockwise)

Preceding gene: 154685585

Following gene: 154685566

Centisome position: 28.58

GC content: 48.14

Gene sequence:

>993_bases
ATGAAGAAAACGATTTTTTCAGGCATTCAGCCGAGCGGTTCCGTTACCCTCGGCAACTACATCGGCGCAATGAAGCAATT
TGTTGATTTGCAGCATGACTACAACGGCTACTTCTGTATTGTCGATCAGCATGCGATTACGGTTCCGCAGGATCGGCTTG
AGCTGCGGAAGAACATTCGCAATCTCGCGGCTCTTTACGTGGCCGTCGGACTTGATCCCGAGAAAGCGACCCTCTTTATC
CAGTCGGAGGTTCCCGCTCATGCCCAGGCGGGGTGGATGCTCCAATGCGTCGCATATATCGGCGAGCTTGAGCGGATGAC
GCAATTTAAAGATAAGTCAAAGGGCAAAGAAGCCGTCGTGTCAGGACTGTTAACCTATCCGCCGCTGATGGCCGGCGATA
TTTTACTGTACGGAACGGATCTTGTTCCGGTCGGAGAAGATCAAAAACAGCATCTTGAACTGACCCGCAACCTGGCGGAA
CGCTTCAATAAAAAATACAATGACATCTTCACGATTCCTGAGGTGAAAATTCCTGAATCAGGCGCGCGCATCATGTCACT
GGCTGATCCGCTCAAAAAAATGAGCAAATCAGATCCGAACCAAAAGGCATACATCACGCTGCTTGATGAGCCGAAGCAGC
TCGAGAAGAAAATCAAGAGCGCCGTGACTGATTCTGAAGGAATTGTAAAGTATGATAAAGAAAACAAACCGGGCGTTTCT
AATCTTTTGACGATCTATTCTATTTTAGGAAACACATCAATTGAAGAATTAGAAGCTAAATATGAAGGCAAAGGGTACGG
TGAATTCAAAAGCGATTTAGCCGAAGTCGTTATCGGCGCATTGACACCGATCCAAGAGCGCTACCGTGAATTAATTGAGA
GCGACGAGCTTGACCGCATTCTCGACGAAGGAGCGGCGCGCGCAAACAAAACGGCCGGCAAAATGGTGAAGAAAATGGAA
AACGCCATGGGTCTCGGACGGAAAAGAAGATAA

Upstream 100 bases:

>100_bases
GTAATGGAATAATCAGGGTGGCACCACGGTTCATTCGTCCCTTTTTTCTACGGGAAGAATGGGCTTTTTTTATTATGTTT
TAAGAAATGAGGTAAGAACT

Downstream 100 bases:

>100_bases
AGAAAAGAGGCGGGAGAATCCCCGCCTCTTTTTTAGTTCACTTTTGATTCCTGCTCCATTTCCCAAAGCTTTTCGAAAAA
CGGCTGCCCTTTAATCAAAT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTIFSGIQPSGSVTLGNYIGAMKQFVDLQHDYNGYFCIVDQHAITVPQDRLELRKNIRNLAALYVAVGLDPEKATLFI
QSEVPAHAQAGWMLQCVAYIGELERMTQFKDKSKGKEAVVSGLLTYPPLMAGDILLYGTDLVPVGEDQKQHLELTRNLAE
RFNKKYNDIFTIPEVKIPESGARIMSLADPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVTDSEGIVKYDKENKPGVS
NLLTIYSILGNTSIEELEAKYEGKGYGEFKSDLAEVVIGALTPIQERYRELIESDELDRILDEGAARANKTAGKMVKKME
NAMGLGRKRR

Sequences:

>Translated_330_residues
MKKTIFSGIQPSGSVTLGNYIGAMKQFVDLQHDYNGYFCIVDQHAITVPQDRLELRKNIRNLAALYVAVGLDPEKATLFI
QSEVPAHAQAGWMLQCVAYIGELERMTQFKDKSKGKEAVVSGLLTYPPLMAGDILLYGTDLVPVGEDQKQHLELTRNLAE
RFNKKYNDIFTIPEVKIPESGARIMSLADPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVTDSEGIVKYDKENKPGVS
NLLTIYSILGNTSIEELEAKYEGKGYGEFKSDLAEVVIGALTPIQERYRELIESDELDRILDEGAARANKTAGKMVKKME
NAMGLGRKRR
>Mature_330_residues
MKKTIFSGIQPSGSVTLGNYIGAMKQFVDLQHDYNGYFCIVDQHAITVPQDRLELRKNIRNLAALYVAVGLDPEKATLFI
QSEVPAHAQAGWMLQCVAYIGELERMTQFKDKSKGKEAVVSGLLTYPPLMAGDILLYGTDLVPVGEDQKQHLELTRNLAE
RFNKKYNDIFTIPEVKIPESGARIMSLADPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVTDSEGIVKYDKENKPGVS
NLLTIYSILGNTSIEELEAKYEGKGYGEFKSDLAEVVIGALTPIQERYRELIESDELDRILDEGAARANKTAGKMVKKME
NAMGLGRKRR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=327, Percent_Identity=41.2844036697248, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI41352700, Length=175, Percent_Identity=50.2857142857143, Blast_Score=181, Evalue=8e-46,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=55.3191489361702, Blast_Score=364, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982800, Length=328, Percent_Identity=39.0243902439024, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI71982793, Length=328, Percent_Identity=39.0243902439024, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=41.5697674418605, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24666151, Length=327, Percent_Identity=39.4495412844037, Blast_Score=242, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36865; Mature: 36865

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIFSGIQPSGSVTLGNYIGAMKQFVDLQHDYNGYFCIVDQHAITVPQDRLELRKNIR
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCCHHHHHHHHHHH
NLAALYVAVGLDPEKATLFIQSEVPAHAQAGWMLQCVAYIGELERMTQFKDKSKGKEAVV
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGLLTYPPLMAGDILLYGTDLVPVGEDQKQHLELTRNLAERFNKKYNDIFTIPEVKIPES
HHHHHCCCHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCC
GARIMSLADPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVTDSEGIVKYDKENKPGVS
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCHH
NLLTIYSILGNTSIEELEAKYEGKGYGEFKSDLAEVVIGALTPIQERYRELIESDELDRI
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHH
LDEGAARANKTAGKMVKKMENAMGLGRKRR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKTIFSGIQPSGSVTLGNYIGAMKQFVDLQHDYNGYFCIVDQHAITVPQDRLELRKNIR
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCCHHHHHHHHHHH
NLAALYVAVGLDPEKATLFIQSEVPAHAQAGWMLQCVAYIGELERMTQFKDKSKGKEAVV
HHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGLLTYPPLMAGDILLYGTDLVPVGEDQKQHLELTRNLAERFNKKYNDIFTIPEVKIPES
HHHHHCCCHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCC
GARIMSLADPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVTDSEGIVKYDKENKPGVS
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCHH
NLLTIYSILGNTSIEELEAKYEGKGYGEFKSDLAEVVIGALTPIQERYRELIESDELDRI
HHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHH
LDEGAARANKTAGKMVKKMENAMGLGRKRR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3149612; 9384377; 2494170 [H]