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The map label for this gene is yisQ [H]

Identifier: 154685531

GI number: 154685531

Start: 1075557

End: 1076924

Strand: Reverse

Name: yisQ [H]

Synonym: RBAM_010970

Alternate gene names: 154685531

Gene position: 1076924-1075557 (Counterclockwise)

Preceding gene: 154685533

Following gene: 154685528

Centisome position: 27.48

GC content: 46.86

Gene sequence:

>1368_bases
ATGAAACAAGCGATTTTAAAACGGGCTGCGTTCAAACAATCCTCTGATCACAAACTCTCATTATACGCGCTGACTTGGCC
GATATTTATTGAGGTTTCATTATATATGTTTATGGGAAACGCCGACACTCTTATGCTTAGCCAATACTCTGACAACAGTG
TGGCGGCCGTGGGTGTCAGCAATCAGATTTTAAATTTAATTATCGTGATGTTCAGCTTTATCGCAACGGGTACGACAATT
GTGATTTCACAGTTTTTAGGCTCTAAACAGAAAAAAGAGGCGCAGGAAGTGGCTTATGTATCAATAGGAGCGAACTTTGT
CATCAGTCTCGCCATCAGCGCCGCCATATTTTTTGCGGCCGTTCCGCTGCTTCATGTGATGGGTCTTTCCAATGAATTGA
TGCCGGATGCCAAAGTCTTTTTGCAGGTGGTCGGCGGGCTGTCCTTCATTCAGGCTTTGATTATGACGTTCAGCGCCATT
TTAAAAAGCTATGGTCATACGAAGGATACGATGTTCGTTACGATCGGGATGAATATTTTAAATATTGCCGGAAACTTTCT
TGTCATTTTCGGGCCGCTCGGCCTTCCGGTGTTAGGCGTCGCCGGTGTTGCGATGTCAACGTCCTTCGCGCGGATCATCG
GGCTGATTGCGATGATTGTGATCGTCAAAAAACGCATCGGACTCGGTCTGACATGGCAAAAGATTTTTCACGTCCATAAA
GAGCACTTGCGGAAACTCCTGAAAATCGGGATTCCGTCTGCCGGCGAACAGCTGTCTTACAACATTTCGCAAATGGTTGT
CACTTATTTTATCGCCATTATGGGCGCTCAGGCGCTTACAACAAAGGTTTATACACAAAACATCACCATGTTTATCCTGC
TGTTCGGAACGGCAATCAGCCAGGGCACACAGATTTTGATCGGCAGATATATCGGCGCCAAACGGTTTGACGACGCTTAT
GACCGCTGCATGAAAAGTCTGTACTGGGCGCTTGGCATTGCCGCTTTGACATCCGTGATCATGACTTTGTTTTCAAAGCA
GCTGATCGGAATTTTCACAAGCAGCCCTGACATTATTGCGACGGCGAGCATGCTGATCGCCATGACGATCATTCTTGAGC
CCGGCCGTTCATTCAATGTCATTATCATCAACTCGCTGCGGGCTGCCGGAGATGCAAAATTTCCCGTCTACATGGCGATG
ATTTCCATGTGGGGTATCGGACTGCCTCTCGCTTATCTGTTCGGCATCCATTTCGGATTAGGGCTTATGGGCATCTGGAT
TTCATTTATCGCGGATGAATGGGTCAGAGGCATCCTTATGTACAGAAGATGGCGGTCGCGGATTTGGATTCAAAAAGGGA
TTGCATAA

Upstream 100 bases:

>100_bases
TCGGATTTTTGCAAGAAGTTTCGTTTCTCTCCCTTTTTATTATAAGAAAATGGAGGTACACTTTTAAACGTTGATTTTTT
CAGGAAAGGGGTTAAAAGAA

Downstream 100 bases:

>100_bases
ACGCCCGAAGCTTCGTTATGAAGCCGGGCGTTTTTTTATGCTTGTGAAAGCTGTTGTCTCATGTCACCGAGCTCTGACCG
GTAATGTGCCGCTAAACCGG

Product: YisQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTI
VISQFLGSKQKKEAQEVAYVSIGANFVISLAISAAIFFAAVPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAI
LKSYGHTKDTMFVTIGMNILNIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIVKKRIGLGLTWQKIFHVHK
EHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGAKRFDDAY
DRCMKSLYWALGIAALTSVIMTLFSKQLIGIFTSSPDIIATASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAM
ISMWGIGLPLAYLFGIHFGLGLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA

Sequences:

>Translated_455_residues
MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTI
VISQFLGSKQKKEAQEVAYVSIGANFVISLAISAAIFFAAVPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAI
LKSYGHTKDTMFVTIGMNILNIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIVKKRIGLGLTWQKIFHVHK
EHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGAKRFDDAY
DRCMKSLYWALGIAALTSVIMTLFSKQLIGIFTSSPDIIATASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAM
ISMWGIGLPLAYLFGIHFGLGLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA
>Mature_455_residues
MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTI
VISQFLGSKQKKEAQEVAYVSIGANFVISLAISAAIFFAAVPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAI
LKSYGHTKDTMFVTIGMNILNIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIVKKRIGLGLTWQKIFHVHK
EHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGAKRFDDAY
DRCMKSLYWALGIAALTSVIMTLFSKQLIGIFTSSPDIIATASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAM
ISMWGIGLPLAYLFGIHFGLGLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=456, Percent_Identity=25.219298245614, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI48994890, Length=453, Percent_Identity=22.5165562913907, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320545, Length=398, Percent_Identity=23.3668341708543, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50013; Mature: 50013

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVS
CCHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCH
NQILNLIIVMFSFIATGTTIVISQFLGSKQKKEAQEVAYVSIGANFVISLAISAAIFFAA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHH
VPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAILKSYGHTKDTMFVTIGMNIL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
NIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIVKKRIGLGLTWQKIFHVHK
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTTKVYTQNITMFILLFGTAIS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
QGTQILIGRYIGAKRFDDAYDRCMKSLYWALGIAALTSVIMTLFSKQLIGIFTSSPDIIA
CCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
TASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHFGL
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
GLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLMLSQYSDNSVAAVGVS
CCHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCH
NQILNLIIVMFSFIATGTTIVISQFLGSKQKKEAQEVAYVSIGANFVISLAISAAIFFAA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHH
VPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAILKSYGHTKDTMFVTIGMNIL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHH
NIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIVKKRIGLGLTWQKIFHVHK
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTTKVYTQNITMFILLFGTAIS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
QGTQILIGRYIGAKRFDDAYDRCMKSLYWALGIAALTSVIMTLFSKQLIGIFTSSPDIIA
CCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
TASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHFGL
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
GLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]