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The map label for this gene is serC [H]

Identifier: 154685460

GI number: 154685460

Start: 1002796

End: 1003875

Strand: Reverse

Name: serC [H]

Synonym: RBAM_010260

Alternate gene names: 154685460

Gene position: 1003875-1002796 (Counterclockwise)

Preceding gene: 154685461

Following gene: 154685459

Centisome position: 25.62

GC content: 50.37

Gene sequence:

>1080_bases
ATGGAACGTACAACGAATTTCAATGCAGGACCCGCAGCCCTTCCACTGGATGTGCTGCAAAAAGCACAAAAAGAATTTGT
CAACTTCAATGATACCGGCATGTCCGTCATGGAGCTGTCCCACCGAAGCACGGAATATGATGCGGTGCACCAAAAAGCCA
AAAGCCTTCTGAAAGAACTGATGGATATTCCCGACGATTACGATATTTTATTTCTTCAAGGCGGCGCAAGCCTTCAATTC
TCCATGCTGCCGATGAACTTTTTAACGCCGGAGCAAACGGCGCACTTCATCGTAACGGGCGCATGGTCTGAAAAAGCACT
CGCCGAGGCGAAACTGTTCGGAAACACATCCGTCACGGCAACAAGCGCAGATTCAAACCACAACCACATACCGGAAGCGG
ACCTCTCAGGAATCAAAGACGGCGCCTACCTGCATATTACGTCAAACAACACGATTTTCGGAACGCAGTGGAAAGAGTTC
CCGAATTCAACAATCCCGCTCGTAGCCGACATGTCAAGCGACATCCTGAGCAGAAAAATTGATGTCAAAACGTTTGATGT
CATCTATGGCGGAGCCCAGAAAAACCTCGGGCCGTCCGGCGTCACGGTCGTCATCATGAAAAAATCATGGCTTGAAAACG
AAAACGCCAACGTCCCTAAAATGTTGAAATACTCCACTCACACAAAAGCCGATTCACTGTATAATACGCCGCCTACATTT
GCGATTTATATGCTGAGCCTCGTCCTTGAATGGCTGGCTGAAAACGGCGGTGTCGAAGCGGCTGAACGGCGCAATCAGGA
AAAGGCCGATGTCCTGTACGGCACAATCGACGCAAGCGGCGGGTTTTACGCGGGGCATGCCGCAAAAGACAGCCGTTCTC
ACATGAACGTCACGTTCACCCTCCGCGACAGCAGTCTCACGAAAAAATTCGTTGAAGAAGCGAAAGCGGCTAAAATGACC
GGACTCGGAGGCCACCGCTCAGTCGGAGGCTGCAGGGCGTCTATCTACAACGCCGTCAGCCTGGCTGATTGTGAAAAACT
GGCTCAGTTTATGAGAAAGTTCCAGCAGGAAAACGAATAA

Upstream 100 bases:

>100_bases
CATAAATTATATTTTTTTATATCAAAAAAATCAAAAAATTGTGATAGGATAATTGTATTATTTCTTACACTAAAGCGGAA
AACAGGGAGAGATCGTAAAC

Downstream 100 bases:

>100_bases
ATTTCTTCTAACATAACGGTTCCTTTGATATACTGTTTGCATATCAATTTTTCCGGCCATCGCAATAAATGACGAGCATA
TTATTGGATGGCGAAAAAGC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT; Vegetative protein 234; VEG234 [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MERTTNFNAGPAALPLDVLQKAQKEFVNFNDTGMSVMELSHRSTEYDAVHQKAKSLLKELMDIPDDYDILFLQGGASLQF
SMLPMNFLTPEQTAHFIVTGAWSEKALAEAKLFGNTSVTATSADSNHNHIPEADLSGIKDGAYLHITSNNTIFGTQWKEF
PNSTIPLVADMSSDILSRKIDVKTFDVIYGGAQKNLGPSGVTVVIMKKSWLENENANVPKMLKYSTHTKADSLYNTPPTF
AIYMLSLVLEWLAENGGVEAAERRNQEKADVLYGTIDASGGFYAGHAAKDSRSHMNVTFTLRDSSLTKKFVEEAKAAKMT
GLGGHRSVGGCRASIYNAVSLADCEKLAQFMRKFQQENE

Sequences:

>Translated_359_residues
MERTTNFNAGPAALPLDVLQKAQKEFVNFNDTGMSVMELSHRSTEYDAVHQKAKSLLKELMDIPDDYDILFLQGGASLQF
SMLPMNFLTPEQTAHFIVTGAWSEKALAEAKLFGNTSVTATSADSNHNHIPEADLSGIKDGAYLHITSNNTIFGTQWKEF
PNSTIPLVADMSSDILSRKIDVKTFDVIYGGAQKNLGPSGVTVVIMKKSWLENENANVPKMLKYSTHTKADSLYNTPPTF
AIYMLSLVLEWLAENGGVEAAERRNQEKADVLYGTIDASGGFYAGHAAKDSRSHMNVTFTLRDSSLTKKFVEEAKAAKMT
GLGGHRSVGGCRASIYNAVSLADCEKLAQFMRKFQQENE
>Mature_359_residues
MERTTNFNAGPAALPLDVLQKAQKEFVNFNDTGMSVMELSHRSTEYDAVHQKAKSLLKELMDIPDDYDILFLQGGASLQF
SMLPMNFLTPEQTAHFIVTGAWSEKALAEAKLFGNTSVTATSADSNHNHIPEADLSGIKDGAYLHITSNNTIFGTQWKEF
PNSTIPLVADMSSDILSRKIDVKTFDVIYGGAQKNLGPSGVTVVIMKKSWLENENANVPKMLKYSTHTKADSLYNTPPTF
AIYMLSLVLEWLAENGGVEAAERRNQEKADVLYGTIDASGGFYAGHAAKDSRSHMNVTFTLRDSSLTKKFVEEAKAAKMT
GLGGHRSVGGCRASIYNAVSLADCEKLAQFMRKFQQENE

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=366, Percent_Identity=41.2568306010929, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI10863955, Length=362, Percent_Identity=37.5690607734807, Blast_Score=253, Evalue=2e-67,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=42.5414364640884, Blast_Score=293, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=41.9889502762431, Blast_Score=283, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6324758, Length=389, Percent_Identity=40.3598971722365, Blast_Score=278, Evalue=1e-75,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=40.7202216066482, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39470; Mature: 39470

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTTNFNAGPAALPLDVLQKAQKEFVNFNDTGMSVMELSHRSTEYDAVHQKAKSLLKEL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
MDIPDDYDILFLQGGASLQFSMLPMNFLTPEQTAHFIVTGAWSEKALAEAKLFGNTSVTA
HCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEE
TSADSNHNHIPEADLSGIKDGAYLHITSNNTIFGTQWKEFPNSTIPLVADMSSDILSRKI
ECCCCCCCCCCCCHHCCCCCCEEEEEECCCEEECCCHHHCCCCCCCEEECCHHHHHHHCC
DVKTFDVIYGGAQKNLGPSGVTVVIMKKSWLENENANVPKMLKYSTHTKADSLYNTPPTF
CCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHH
AIYMLSLVLEWLAENGGVEAAERRNQEKADVLYGTIDASGGFYAGHAAKDSRSHMNVTFT
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEE
LRDSSLTKKFVEEAKAAKMTGLGGHRSVGGCRASIYNAVSLADCEKLAQFMRKFQQENE
EECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERTTNFNAGPAALPLDVLQKAQKEFVNFNDTGMSVMELSHRSTEYDAVHQKAKSLLKEL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
MDIPDDYDILFLQGGASLQFSMLPMNFLTPEQTAHFIVTGAWSEKALAEAKLFGNTSVTA
HCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEE
TSADSNHNHIPEADLSGIKDGAYLHITSNNTIFGTQWKEFPNSTIPLVADMSSDILSRKI
ECCCCCCCCCCCCHHCCCCCCEEEEEECCCEEECCCHHHCCCCCCCEEECCHHHHHHHCC
DVKTFDVIYGGAQKNLGPSGVTVVIMKKSWLENENANVPKMLKYSTHTKADSLYNTPPTF
CCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHH
AIYMLSLVLEWLAENGGVEAAERRNQEKADVLYGTIDASGGFYAGHAAKDSRSHMNVTFT
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEE
LRDSSLTKKFVEEAKAAKMTGLGGHRSVGGCRASIYNAVSLADCEKLAQFMRKFQQENE
EECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]