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The map label for this gene is yfkC [H]

Identifier: 154685271

GI number: 154685271

Start: 807822

End: 808655

Strand: Reverse

Name: yfkC [H]

Synonym: RBAM_008170

Alternate gene names: 154685271

Gene position: 808655-807822 (Counterclockwise)

Preceding gene: 154685272

Following gene: 154685268

Centisome position: 20.64

GC content: 46.28

Gene sequence:

>834_bases
ATGGAAACGACAATTACGGACATTTTGAAAAGCAAAGTGGTTGAGATCATCATCGTCGCTCTCGTGCTTTACGCCGGTGT
TTTTCTGATCAACCGCTTTGTCCAGGTGTTATTTAAACGCACGGATTTCTTGGAGGAACGGAAAGGGAAAACGATTGAAA
GCCTCGTCCGATCCATCACCCAGTATACGGCGACGATCGGTTTTATCTTTTACGTCATTTCTTTATTCGTTCATGATTTC
GGCCGAATTTTAGCCGGGGCGGGTGTTGCCGGTATCGTCATCGGTTTCGGCGCCCAGTCGTTAATCAAGGACATATTGGC
CGGTGTCTTTTTAATATACGAACGCCAGCTTCATAAAGGTGATTATGTGACGATTAACAATCTGTTCAACGGCACAGTCG
AAGAAATCGGACTCCGTTCCCTCCAGATCCGTGAGTGGACCGGCAAGCTGCTTACCATATCTAACGGTGAGGTCAGACAG
CTTCAAAACTATAACATTGATTTTATGCGGATTACCGAGTCCGTCGTGATCAGTTACAAGGAAGATCCCGAGCGGGTATA
TGCCGTCTTAGAAAAAGCCTGCGATATGCTCAATGATGAGCTTCGCGATTCACTGAAGCGGGATGAATTTCTCAATGCGA
CGGAGCCGTTTCAAGTGCATGGAATTATGAGTCTGAACAAATTAACCAGAGGCATTGAATTTACAGTGAAAGGCATGGTT
CAAGACACAGAATACTTCTCGGCGAGCCTTGCGGTGAGACGCGTTCTTGCCCGGGAGCTGTACAACAACAATCTGCAATT
GCTCGAGGAAATGTATCACACACAAAAAAGCTGA

Upstream 100 bases:

>100_bases
CTGCACAAACGTCCGGTGCCTCGGCCCGAACGTCCTTGTCAAAAACAGTTATTATCAGGACACAGATTTTTCATTACGAA
AAGCCAGAGGTTAACAAAAG

Downstream 100 bases:

>100_bases
TTCCCGAACCGGAATCAGCTTTTTTTATTTATCTCGGCTGCGCTGTCATTTGAAAACCGAATGTGACGTGATCCTGCACC
GGAATCCAAGCTCCGATTCC

Product: YfkC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
METTITDILKSKVVEIIIVALVLYAGVFLINRFVQVLFKRTDFLEERKGKTIESLVRSITQYTATIGFIFYVISLFVHDF
GRILAGAGVAGIVIGFGAQSLIKDILAGVFLIYERQLHKGDYVTINNLFNGTVEEIGLRSLQIREWTGKLLTISNGEVRQ
LQNYNIDFMRITESVVISYKEDPERVYAVLEKACDMLNDELRDSLKRDEFLNATEPFQVHGIMSLNKLTRGIEFTVKGMV
QDTEYFSASLAVRRVLARELYNNNLQLLEEMYHTQKS

Sequences:

>Translated_277_residues
METTITDILKSKVVEIIIVALVLYAGVFLINRFVQVLFKRTDFLEERKGKTIESLVRSITQYTATIGFIFYVISLFVHDF
GRILAGAGVAGIVIGFGAQSLIKDILAGVFLIYERQLHKGDYVTINNLFNGTVEEIGLRSLQIREWTGKLLTISNGEVRQ
LQNYNIDFMRITESVVISYKEDPERVYAVLEKACDMLNDELRDSLKRDEFLNATEPFQVHGIMSLNKLTRGIEFTVKGMV
QDTEYFSASLAVRRVLARELYNNNLQLLEEMYHTQKS
>Mature_277_residues
METTITDILKSKVVEIIIVALVLYAGVFLINRFVQVLFKRTDFLEERKGKTIESLVRSITQYTATIGFIFYVISLFVHDF
GRILAGAGVAGIVIGFGAQSLIKDILAGVFLIYERQLHKGDYVTINNLFNGTVEEIGLRSLQIREWTGKLLTISNGEVRQ
LQNYNIDFMRITESVVISYKEDPERVYAVLEKACDMLNDELRDSLKRDEFLNATEPFQVHGIMSLNKLTRGIEFTVKGMV
QDTEYFSASLAVRRVLARELYNNNLQLLEEMYHTQKS

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=165, Percent_Identity=32.7272727272727, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31654; Mature: 31654

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTITDILKSKVVEIIIVALVLYAGVFLINRFVQVLFKRTDFLEERKGKTIESLVRSIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QYTATIGFIFYVISLFVHDFGRILAGAGVAGIVIGFGAQSLIKDILAGVFLIYERQLHKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DYVTINNLFNGTVEEIGLRSLQIREWTGKLLTISNGEVRQLQNYNIDFMRITESVVISYK
CEEEEHHHHCCCHHHHCCHHHEEHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHEECC
EDPERVYAVLEKACDMLNDELRDSLKRDEFLNATEPFQVHGIMSLNKLTRGIEFTVKGMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCHHHHHHHHH
QDTEYFSASLAVRRVLARELYNNNLQLLEEMYHTQKS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
METTITDILKSKVVEIIIVALVLYAGVFLINRFVQVLFKRTDFLEERKGKTIESLVRSIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QYTATIGFIFYVISLFVHDFGRILAGAGVAGIVIGFGAQSLIKDILAGVFLIYERQLHKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
DYVTINNLFNGTVEEIGLRSLQIREWTGKLLTISNGEVRQLQNYNIDFMRITESVVISYK
CEEEEHHHHCCCHHHHCCHHHEEHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHEECC
EDPERVYAVLEKACDMLNDELRDSLKRDEFLNATEPFQVHGIMSLNKLTRGIEFTVKGMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCHHHHHHHHH
QDTEYFSASLAVRRVLARELYNNNLQLLEEMYHTQKS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]