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The map label for this gene is ydjL [H]

Identifier: 154685120

GI number: 154685120

Start: 640272

End: 641312

Strand: Reverse

Name: ydjL [H]

Synonym: RBAM_006650

Alternate gene names: 154685120

Gene position: 641312-640272 (Counterclockwise)

Preceding gene: 154685123

Following gene: 154685119

Centisome position: 16.37

GC content: 48.41

Gene sequence:

>1041_bases
ATGAAAGCGGCAAGATGGCACAATCAAAAAGACATTCGAATCGAAAACATTGATGAACCTAAAGCAGAACCGGGTAAAGT
CAAAATTAAAGTCAAATGGTGCGGGATTTGCGGAAGCGACCTTCATGAATATTTGGGAGGCCCGATCTTTATTCCGGTCG
GCAAACCTCATCCGTTAACAAACGAAATGGCGCCCGTCACGATGGGTCACGAATTCTCAGGAGAAGTCGTTGAAGTGGGC
GAAGGCGTCAAAAATTACAGCGTCGGCGACCGTGTCGTCGTGGAACCGATTTTTGCCACACACGGACATCAGGGAGCCTA
TAACCTTGATGAACAAATGGGATTCTTAGGCTTAGCTGGAGGCGGCGGCGGATTTTCTGAATATGTATCCGTTGACGAAG
AATTGCTGTTTAAGCTTCCTGAAGAGCTTTCTTACGAACAGGGCGCGCTTGTTGAGCCGTCAGCGGTAGCGCTTTACGCC
GTCCGCCAAAGCAAATTAAAAGCGGGCGACACGGCGGCAGTTTTTGGCTGCGGACCGATCGGGCTGCTTGTGATTGAAGC
CCTGAAAGCGGCCGGCGCCACAGATATTTACGCGGTTGAACTTTCACCGGAACGTCAGGAAAAAGCGAAAGAACTCGGCG
CTATCATCATTGATCCGTCAAAAACGGACGATGTCGTTGAAGAAATCGCTAAACGCACAAACGGCGGCGTTGATGTTTCT
TATGAAGTAACAGGCGTTCCTGTCGTTCTCCGCCAGGCGATCCAGTCAACAAACATTGCCGGTGAAACGGTTATCGTCAG
CATTTGGGAAAAAGGAGCGGAAATTCATCCGAACGATATCGTTATCAAAGAACGGACCGTAAAAGGCATTATCGGATACC
GTGACATCTTCCCTTCCGTTCTTGCACTGATGAAAGAGGGCTACTTCTCAGCAGATAAGCTCGTCACGAAAAAAATCGTG
CTCGACGATCTGATTGAAGAAGGCTTCGGCGCTTTAATCAAAGAGAAAAACCAAGTGAAAATCTTAGTCAAACCGAACTA
A

Upstream 100 bases:

>100_bases
GAAATCAGGCTTTAGGAAGCAGGCACTTTATTCCTTTTAACCGTGGTTCATATTGATCATGTACCTATACTCGTTTCAAT
CAGACTAGGAGTGATAATCA

Downstream 100 bases:

>100_bases
ATCGTTTAGCTGAATAACAGACACATCCGAAAAAGAGCCGTTCCGGCTCTTTTTTTCATCTCATCGTCTTTCCTTCCTTT
TCCTTTTAAAAATGATCCCC

Product: YdjL

Products: NA

Alternate protein names: Acetoin reductase/2,3-butanediol dehydrogenase; AR/BDH [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKAARWHNQKDIRIENIDEPKAEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVGKPHPLTNEMAPVTMGHEFSGEVVEVG
EGVKNYSVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAGGGGGFSEYVSVDEELLFKLPEELSYEQGALVEPSAVALYA
VRQSKLKAGDTAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQEKAKELGAIIIDPSKTDDVVEEIAKRTNGGVDVS
YEVTGVPVVLRQAIQSTNIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPSVLALMKEGYFSADKLVTKKIV
LDDLIEEGFGALIKEKNQVKILVKPN

Sequences:

>Translated_346_residues
MKAARWHNQKDIRIENIDEPKAEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVGKPHPLTNEMAPVTMGHEFSGEVVEVG
EGVKNYSVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAGGGGGFSEYVSVDEELLFKLPEELSYEQGALVEPSAVALYA
VRQSKLKAGDTAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQEKAKELGAIIIDPSKTDDVVEEIAKRTNGGVDVS
YEVTGVPVVLRQAIQSTNIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPSVLALMKEGYFSADKLVTKKIV
LDDLIEEGFGALIKEKNQVKILVKPN
>Mature_346_residues
MKAARWHNQKDIRIENIDEPKAEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVGKPHPLTNEMAPVTMGHEFSGEVVEVG
EGVKNYSVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAGGGGGFSEYVSVDEELLFKLPEELSYEQGALVEPSAVALYA
VRQSKLKAGDTAAVFGCGPIGLLVIEALKAAGATDIYAVELSPERQEKAKELGAIIIDPSKTDDVVEEIAKRTNGGVDVS
YEVTGVPVVLRQAIQSTNIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPSVLALMKEGYFSADKLVTKKIV
LDDLIEEGFGALIKEKNQVKILVKPN

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=331, Percent_Identity=30.8157099697885, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI4501933, Length=380, Percent_Identity=30.2631578947368, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4501929, Length=379, Percent_Identity=30.0791556728232, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI34577061, Length=380, Percent_Identity=29.4736842105263, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI71565152, Length=385, Percent_Identity=25.7142857142857, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI262073058, Length=365, Percent_Identity=27.3972602739726, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI71743840, Length=365, Percent_Identity=27.3972602739726, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4501939, Length=359, Percent_Identity=25.6267409470752, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI156523966, Length=359, Percent_Identity=25.6267409470752, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI71565154, Length=286, Percent_Identity=28.3216783216783, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1788073, Length=335, Percent_Identity=29.5522388059701, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788075, Length=357, Percent_Identity=29.1316526610644, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787863, Length=318, Percent_Identity=30.8176100628931, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=27.1676300578035, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082125, Length=280, Percent_Identity=29.6428571428571, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788407, Length=317, Percent_Identity=28.0757097791798, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786825, Length=306, Percent_Identity=31.6993464052288, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790718, Length=303, Percent_Identity=28.7128712871287, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI226510992, Length=322, Percent_Identity=27.9503105590062, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786552, Length=376, Percent_Identity=28.1914893617021, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081918, Length=313, Percent_Identity=23.6421725239617, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=335, Percent_Identity=34.0298507462687, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17562878, Length=332, Percent_Identity=32.8313253012048, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71997431, Length=363, Percent_Identity=27.8236914600551, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=361, Percent_Identity=27.1468144044321, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565904, Length=312, Percent_Identity=27.5641025641026, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=298, Percent_Identity=24.8322147651007, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=270, Percent_Identity=22.962962962963, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319257, Length=378, Percent_Identity=34.9206349206349, Blast_Score=215, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6319258, Length=377, Percent_Identity=36.3395225464191, Blast_Score=208, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6323099, Length=326, Percent_Identity=32.5153374233129, Blast_Score=155, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6319955, Length=326, Percent_Identity=32.5153374233129, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6322619, Length=326, Percent_Identity=32.5153374233129, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320033, Length=310, Percent_Identity=26.1290322580645, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=265, Percent_Identity=26.0377358490566, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=242, Percent_Identity=26.8595041322314, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=274, Percent_Identity=23.7226277372263, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=232, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137530, Length=323, Percent_Identity=32.1981424148607, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17737897, Length=323, Percent_Identity=31.5789473684211, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17737895, Length=353, Percent_Identity=29.4617563739377, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45550770, Length=343, Percent_Identity=23.0320699708455, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551930, Length=343, Percent_Identity=23.0320699708455, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221457811, Length=343, Percent_Identity=23.0320699708455, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.4 [H]

Molecular weight: Translated: 37404; Mature: 37404

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARWHNQKDIRIENIDEPKAEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVGKPHPLT
CCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCCEEEECCCCCCCC
NEMAPVTMGHEFSGEVVEVGEGVKNYSVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAG
CCCCCEEECCCCCCCCEECCCCCCCCCCCCEEEEEEHHHCCCCCCCCCHHHCCCEEEEEC
GGGGFSEYVSVDEELLFKLPEELSYEQGALVEPSAVALYAVRQSKLKAGDTAAVFGCGPI
CCCCHHHHHHHCHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHH
GLLVIEALKAAGATDIYAVELSPERQEKAKELGAIIIDPSKTDDVVEEIAKRTNGGVDVS
HHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCEEEE
YEVTGVPVVLRQAIQSTNIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPSV
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
LALMKEGYFSADKLVTKKIVLDDLIEEGFGALIKEKNQVKILVKPN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MKAARWHNQKDIRIENIDEPKAEPGKVKIKVKWCGICGSDLHEYLGGPIFIPVGKPHPLT
CCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCCEEEECCCCCCCC
NEMAPVTMGHEFSGEVVEVGEGVKNYSVGDRVVVEPIFATHGHQGAYNLDEQMGFLGLAG
CCCCCEEECCCCCCCCEECCCCCCCCCCCCEEEEEEHHHCCCCCCCCCHHHCCCEEEEEC
GGGGFSEYVSVDEELLFKLPEELSYEQGALVEPSAVALYAVRQSKLKAGDTAAVFGCGPI
CCCCHHHHHHHCHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHH
GLLVIEALKAAGATDIYAVELSPERQEKAKELGAIIIDPSKTDDVVEEIAKRTNGGVDVS
HHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCEEEE
YEVTGVPVVLRQAIQSTNIAGETVIVSIWEKGAEIHPNDIVIKERTVKGIIGYRDIFPSV
EEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
LALMKEGYFSADKLVTKKIVLDDLIEEGFGALIKEKNQVKILVKPN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]